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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of DNA biosynthetic process
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Accession:GO:2000573 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
Synonyms:exact_synonym: positive regulation of DNA anabolism;   positive regulation of DNA biosynthesis;   positive regulation of DNA formation;   positive regulation of DNA synthesis

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positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:19254952 RGD:5509898 NCBI chr10:55,146,887...55,154,854 JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:156,074,747...156,084,680 JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:17267544 RGD:2303063 NCBI chr 2:215,023,785...215,287,351 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:16005543 RGD:5131269 NCBI chr 4:84,222,897...84,265,924 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IMP RGD PMID:20439821 RGD:7829726 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:22446327 RGD:10401140 NCBI chr20:3,547,702...3,585,064 JBrowse link
G Egf epidermal growth factor IDA RGD PMID:3093142 RGD:10395243 NCBI chr 2:218,219,408...218,302,370 JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO UniProtKB:Q9H3U7 (PMID:16774925) RGD PMID:16774925 NCBI chr 2:120,236,328...120,290,673 JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
ISS		 (PMID:21653700)
GO_REF:0000024		 RGD
UniProt		 PMID:21653700 GO_REF:0000024 NCBI chr17:9,461,541...9,476,268 JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:16937468 RGD:9685728 NCBI chr10:13,718,489...13,721,782 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:12721208 RGD:10045365 NCBI chr11:62,498,997...62,648,665 JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:2531289) RGD PMID:2531289 NCBI chr 4:18,673,736...18,745,582 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISS
ISO		 GO_REF:0000024
(PMID:9924025)		 UniProt
RGD		 PMID:9924025 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633 JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) RGD PMID:17942966 MGI:5009390 NCBI chr 1:140,900,886...141,078,844 JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 IMP RGD PMID:12890786 RGD:7775030 NCBI chr  X:107,116,308...107,374,342 JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10644978 PMID:10734101 PMID:11788434 PMID:12070119 PMID:16530387 PMID:17942966 PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284758|PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 MGI:5284758 NCBI chr18:54,500,002...54,538,843 JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306299|PMID:17226786)		 UniProt
RGD		 PMID:17226786 GO_REF:0000024 MGI:5306299 NCBI chr 1:77,513,625...77,542,386 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:21451101 RGD:10041071 NCBI chr15:40,360,722...40,481,235 JBrowse link
G Rgcc regulator of cell cycle involved_in IDA PMID:9756947 BHF-UCL PMID:9756947 RGD:633887 NCBI chr15:54,662,483...54,675,320 JBrowse link
G Smoc2 SPARC related modular calcium binding 2 involved_in ISO UniProtKB:P09038|UniProtKB:P15692-4 (PMID:16774925) RGD PMID:16774925 NCBI chr 1:55,262,472...55,391,804 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr 3:146,091,969...146,139,492 JBrowse link
G Tnf tumor necrosis factor IDA RGD PMID:9395232 RGD:14696805 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO UniProtKB:Q9H3U7 (PMID:16774925) RGD PMID:16774925 NCBI chr 9:14,955,300...14,970,641 JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chtf18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr10:14,743,006...14,751,044 JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr19:34,782,005...34,792,306 JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr 7:86,482,588...86,498,212 JBrowse link
G Npm1 nucleophosmin 1 IDA RGD PMID:8123045 RGD:11535022 NCBI chr10:17,741,512...17,751,626 JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr 3:119,499,039...119,502,911 JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) RGD PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr10:91,712,586...91,723,008 JBrowse link
G Rfc2 replication factor C subunit 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr12:22,120,449...22,133,576 JBrowse link
G Rfc3 replication factor C subunit 3 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:1,000,987...1,011,778 JBrowse link
G Rfc4 replication factor C subunit 4 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr11:77,749,642...77,764,123 JBrowse link
G Rfc5 replication factor C subunit 5 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:39,207,484...39,217,041 JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA		 (PMID:17237768)
PMID:21873635		 RGD PMID:17237768, PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481 JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:53,744,290...53,750,831 JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:52,692,725...52,705,478 JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732 JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(MGI:5428344|PMID:22723415)		 Ensembl
RGD		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:25467444)
MGI:3849598 (MGI:3047190|PMID:15240872)		 RGD PMID:15240872 PMID:25467444 MGI:3047190
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16545136) RGD PMID:16545136 NCBI chr 3:100,512,317...100,524,001 JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:19015635), (PMID:20938050) RGD PMID:19015635 PMID:20938050 NCBI chr 7:68,400,287...68,530,269 JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:129,702,376...129,707,907 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 9:15,432,986...15,438,358 JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (PMID:20629177) RGD PMID:20629177 NCBI chr 5:70,278,843...70,283,751 JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211 JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358 JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640 JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5810267|PMID:9637678) RGD PMID:9637678 MGI:5810267 NCBI chr 7:93,593,705...93,598,633 JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO
IEA		 (PMID:27510903)
GO_REF:0000107		 RGD
Ensembl		 PMID:27510903 GO_REF:0000107 NCBI chr16:22,837,586...22,868,293 JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063 JBrowse link
G Nek7 NIMA-related kinase 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374 JBrowse link
G Nvl nuclear VCP-like involved_in ISO
IBA		 (PMID:22226966)
PMID:21873635		 RGD PMID:22226966, PMID:21873635 RGD:13792537 NCBI chr13:92,851,023...92,906,749 JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 involved_in IMP
IBA		 PMID:12772192
PMID:21873635		 UniProt
GO_Central		 PMID:12772192, PMID:21873635 RGD:8553456, RGD:13792537 NCBI chr14:16,468,309...16,577,339 JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878) RGD PMID:26482878 NCBI chr10:1,410,636...1,548,573 JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr20:36,965,172...37,062,190 JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:15181449), (PMID:16043710), (PMID:17237768) RGD PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 4:54,205,330...54,263,137 JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049 JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)		 RGD PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr 7:490,698...507,759 JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650) RGD PMID:12782650 NCBI chr16:57,223,174...57,370,740 JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6189679|PMID:29804836)
(PMID:19179534), (PMID:23685356), (PMID:25467444), (PMID:29804836)		 UniProt
RGD		 PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 GO_REF:0000024 MGI:6189679 NCBI chr10:54,282,092...54,299,908 JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) RGD PMID:17237768 NCBI chr19:33,586,739...33,589,481 JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:53,828,741...53,932,773 JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:96,426,704...96,524,152 JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:53,744,290...53,750,831 JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:52,692,725...52,705,478 JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:173,765,792...173,790,353 JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732 JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:82,591,750...82,602,903 JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:26,872,736...26,883,125 JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,989,232...118,006,478 JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:26,710,370...26,722,079 JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(MGI:5428344|PMID:22723415)		 Ensembl
RGD		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (MGI:3047190|PMID:15240872) RGD PMID:15240872 MGI:3047190
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792 JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633 JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610 JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211 JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358 JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640 JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059 JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063 JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374 JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878 PMID:26950371 NCBI chr10:1,410,636...1,548,573 JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr20:36,965,172...37,062,190 JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921 JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:54,205,330...54,263,137 JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049 JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809 JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (MGI:3774867|PMID:17982445) RGD PMID:17982445 MGI:3774867 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:57,223,174...57,370,740 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) RGD PMID:19188702 NCBI chr 9:73,955,220...74,044,020 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      biosynthetic process 6127
        positive regulation of biosynthetic process 2084
          positive regulation of macromolecule biosynthetic process 1918
            positive regulation of DNA biosynthetic process 77
              positive regulation of DNA amplification 0
              positive regulation of DNA-directed DNA polymerase activity 10
              positive regulation of error-prone translesion synthesis 0
              positive regulation of reverse transcription 0
              positive regulation of telomerase activity 33
              positive regulation of telomere maintenance via telomerase 33
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10753
        cellular aromatic compound metabolic process 5636
          nucleobase-containing compound metabolic process 5419
            nucleic acid metabolic process 4929
              DNA metabolic process 883
                regulation of DNA metabolic process 392
                  positive regulation of DNA metabolic process 226
                    positive regulation of DNA biosynthetic process 77
                      positive regulation of DNA amplification 0
                      positive regulation of DNA-directed DNA polymerase activity 10
                      positive regulation of error-prone translesion synthesis 0
                      positive regulation of reverse transcription 0
                      positive regulation of telomerase activity 33
                      positive regulation of telomere maintenance via telomerase 33
paths to the root