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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of excitatory postsynaptic potential
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Accession:GO:2000463 term browser browse the term
Definition:Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Synonyms:exact_synonym: positive regulation of excitatory post-synaptic membrane potential
 related_synonym: positive regulation of EPSP


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positive regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P49582 (PMID:19118188) RGD PMID:19118188 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 IMP RGD PMID:15758177 RGD:9684984 NCBI chr10:105,721,371...105,788,549
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IEA
ISO		 GO_REF:0000107
ComplexPortal:CPX-1134|UniProtKB:P05067-PRO_0000000092 (PMID:19118188)		 Ensembl
RGD		 PMID:19118188 GO_REF:0000107 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cux2 cut-like homeobox 2 involved_in ISO (PMID:20510857) RGD PMID:20510857 NCBI chr12:40,168,402...40,368,303
Ensembl chr12:34,520,959...34,705,806 		JBrowse link
G Dbn1 drebrin 1 IMP RGD PMID:19174472 RGD:10398809 NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IDA
IMP		 PMID:12930820 BHF-UCL
CACAO		 PMID:12930820 PMID:12930820 RGD:8554754, RGD:8554754 NCBI chr10:55,239,397...55,267,780
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Drd4 dopamine receptor D4 IMP RGD PMID:21622557 RGD:7248611 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in IGI PMID:21670302 ParkinsonsUK-UCL PMID:21670302 RGD:10449514 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IMP RGD PMID:23345231 RGD:405100730 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IDA
ISS		 PMID:12930820
PMID:22246434
PMID:19793963
GO_REF:0000114		 ComplexPortal PMID:12930820 PMID:22246434 PMID:19793963 GO_REF:0000114, RGD:8554754, RGD:150521639, RGD:150521643 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in IDA
ISS
IMP		 PMID:12930820
PMID:22246434
GO_REF:0000114		 ComplexPortal
RGD		 PMID:12930820 PMID:22246434 PMID:29339324 GO_REF:0000114, RGD:8554754, RGD:150521639, RGD:401940161 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in IDA
ISS
IMP		 PMID:19793963
GO_REF:0000114		 ComplexPortal
RGD		 PMID:19793963 PMID:29339324 GO_REF:0000114, RGD:150521643, RGD:401940161 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C involved_in IDA PMID:19793963 ComplexPortal PMID:19793963 RGD:150521643 NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D involved_in IDA PMID:19793963 ComplexPortal PMID:19793963 RGD:150521643 NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grip2 glutamate receptor interacting protein 2 involved_in IMP PMID:20083202 UniProt PMID:20083202 RGD:4107359 NCBI chr 4:125,828,609...125,913,693
Ensembl chr 4:124,271,456...124,321,268 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:28975565 RGD:13506836 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:20007479 RGD:4107027 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Neto1 neuropilin and tolloid like 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:3836584 (PMID:21734292)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:21734292 GO_REF:0000033 GO_REF:0000107 NCBI chr18:81,905,455...82,028,730
Ensembl chr18:79,635,633...79,749,030 		JBrowse link
G Neto2 neuropilin and tolloid like 2 NOT|acts_upstream_of_or_within ISO MGI:5141222 (PMID:21734292) RGD PMID:21734292 NCBI chr19:37,517,518...37,588,961
Ensembl chr19:21,344,289...21,417,023 		JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:23114219 RGD:10414080 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nlgn1 neuroligin 1 involved_in IDA
ISO
IMP		 PMID:17582332
PMID:19730411
UniProtKB:Q99K10 (PMID:23143522)
PMID:19628693
(PMID:17582332), (PMID:23143522)		 RGD PMID:17582332 PMID:23143522 PMID:17582332 PMID:19730411 PMID:19628693 RGD:8553502, RGD:8554379, RGD:8554760 NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nlgn2 neuroligin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15620359)		 BHF-UCL
Ensembl
RGD		 PMID:15620359 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,042,175...55,056,578
Ensembl chr10:54,544,588...54,558,434 		JBrowse link
G Nlgn3 neuroligin 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21642956)		 BHF-UCL
RGD		 PMID:21642956 GO_REF:0000024 NCBI chr  X:70,469,251...70,497,380
Ensembl chr  X:66,429,458...66,451,876 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19098102)
(PMID:19822762)		 BHF-UCL
Ensembl
RGD		 PMID:19098102 PMID:19822762 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IMP RGD PMID:31329835 RGD:597015744 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta IMP RGD PMID:33479380 RGD:150519900 NCBI chr12:20,606,066...20,738,766
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IDA PMID:11914719 UniProt PMID:11914719 RGD:8554098 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:18082964) RGD PMID:18082964 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP PMID:11239437 Alzheimers_University_of_Toronto PMID:11239437 RGD:8553497 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Reln reelin involved_in ISO (PMID:17229826), (PMID:20357114), (PMID:21814183) RGD PMID:17229826 PMID:20357114 PMID:21814183 NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:17220354 RGD:13524537 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (PMID:21262469)		 ParkinsonsUK-UCL
RGD		 PMID:21262469 GO_REF:0000024 NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (PMID:21262469)		 ParkinsonsUK-UCL
RGD		 PMID:21262469 GO_REF:0000024 NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18272690)
GO_REF:0000107		 BHF-UCL
RGD
Ensembl		 PMID:18272690 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:103,944,416...103,993,887
Ensembl chr 1:94,808,276...94,855,824 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in ISS
IEA
ISO		 PMID:21795692
GO_REF:0000107
GO_REF:0000024
(PMID:21167025), (PMID:21423165), (PMID:21795692)		 Ensembl
BHF-UCL
RGD		 PMID:21167025 PMID:21423165 PMID:21795692 PMID:21795692 GO_REF:0000024 GO_REF:0000107, RGD:7349315 NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Ssh1 slingshot protein phosphatase 1 IMP RGD PMID:20442266 RGD:11535133 NCBI chr12:48,281,756...48,343,812
Ensembl chr12:42,621,135...42,683,274 		JBrowse link
G Stx1a syntaxin 1A involved_in ISO
IEA		 UniProtKB:O35526|UniProtKB:P61264 (PMID:24133272)
GO_REF:0000107		 RGD
Ensembl		 PMID:24133272 GO_REF:0000107 NCBI chr12:27,278,517...27,306,547
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stx1b syntaxin 1B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
UniProtKB:O35526 (PMID:24133272)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:24133272 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:191,846,016...191,864,878
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Tbc1d24 TBC1 domain family, member 24 IMP RGD PMID:24469796 RGD:11537391 NCBI chr10:13,711,930...13,740,902
Ensembl chr10:13,209,895...13,236,050 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:30676422 RGD:597976449 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Wnt7a Wnt family member 7A involved_in ISO
IEA		 (PMID:21670302)
UniProtKB:Q9WVB9 (PMID:21670302)
GO_REF:0000107		 RGD
Ensembl		 PMID:21670302 GO_REF:0000107 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
positive regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in IEA
ISO		 GO_REF:0000107
ComplexPortal:CPX-1070 (PMID:20395454)		 Ensembl
RGD		 PMID:20395454 GO_REF:0000107 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Afdn afadin, adherens junction formation factor IMP RGD PMID:22948147 RGD:13838731 NCBI chr 1:58,041,065...58,170,505
Ensembl chr 1:53,905,373...54,034,216 		JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 involved_in IMP PMID:26595655 UniProt PMID:26595655 RGD:11085699 NCBI chr11:75,238,706...75,389,748
Ensembl chr11:61,733,144...61,868,348 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        positive regulation of signal transduction 1768
          positive regulation of excitatory postsynaptic potential 45
            positive regulation of mini excitatory postsynaptic potential 3
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          cell-cell signaling 1487
            synaptic signaling 1008
              trans-synaptic signaling 964
                anterograde trans-synaptic signaling 956
                  chemical synaptic transmission 956
                    chemical synaptic transmission, postsynaptic 140
                      excitatory postsynaptic potential 126
                        modulation of excitatory postsynaptic potential 67
                          positive regulation of excitatory postsynaptic potential 45
                            positive regulation of mini excitatory postsynaptic potential 3
paths to the root