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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of excitatory postsynaptic potential
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Accession:GO:2000463 term browser browse the term
Definition:Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Synonyms:exact_synonym: positive regulation of excitatory post-synaptic membrane potential
 related_synonym: positive regulation of EPSP


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positive regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P49582 (PMID:19118188) RGD PMID:19118188 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 IMP RGD PMID:15758177 RGD:9684984 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IEA
ISO
GO_REF:0000107
ComplexPortal:CPX-1134|UniProtKB:P05067:PRO_0000000092 (MGI:5825427|PMID:19118188)
Ensembl
RGD
PMID:19118188 GO_REF:0000107 MGI:5825427 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Cux2 cut-like homeobox 2 involved_in ISO (MGI:4836115|PMID:20510857) RGD PMID:20510857 MGI:4836115 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Dbn1 drebrin 1 IMP RGD PMID:19174472 RGD:10398809 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 involved_in IDA
IMP
PMID:12930820 BHF-UCL
CACAO
PMID:12930820, PMID:12930820 RGD:8554754, RGD:8554754 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Drd4 dopamine receptor D4 IMP RGD PMID:21622557 RGD:7248611 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in IGI PMID:21670302 ParkinsonsUK-UCL PMID:21670302 RGD:10449514 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IDA PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in IDA PMID:12930820 BHF-UCL PMID:12930820 RGD:8554754 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grip2 glutamate receptor interacting protein 2 involved_in IMP PMID:20083202 UniProt PMID:20083202 RGD:4107359 NCBI chr 4:123,585,184...123,636,040
Ensembl chr 4:123,586,231...123,636,040
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:28975565 RGD:13506836 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:20007479 RGD:4107027 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Neto1 neuropilin and tolloid like 1 acts_upstream_of_or_within ISO MGI:3836584 (MGI:5139965|PMID:21734292) RGD PMID:21734292 MGI:5139965 NCBI chr18:83,471,342...83,585,043
Ensembl chr18:83,471,342...83,584,357
JBrowse link
G Neto2 neuropilin and tolloid like 2 NOT|acts_upstream_of_or_within ISO MGI:5141222 (MGI:5139965|PMID:21734292) RGD PMID:21734292 MGI:5139965 NCBI chr19:22,450,579...22,486,530
Ensembl chr19:22,450,030...22,486,531
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:23114219 RGD:10414080 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nlgn1 neuroligin 1 involved_in IDA
ISO
IMP
PMID:17582332
(MGI:3803801|PMID:17582332), (MGI:5493186|PMID:23143522)
PMID:19628693
UniProtKB:Q99K10 (PMID:23143522)
PMID:19730411
RGD PMID:17582332 PMID:23143522, PMID:17582332, PMID:19628693, PMID:19730411 MGI:3803801 MGI:5493186, RGD:8553502, RGD:8554760, RGD:8554379 NCBI chr 2:111,057,291...111,973,681
Ensembl chr 2:111,057,291...111,793,326
JBrowse link
G Nlgn2 neuroligin 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5284797|PMID:15620359)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:15620359 GO_REF:0000024 GO_REF:0000107 MGI:5284797 NCBI chr10:56,431,586...56,444,847
Ensembl chr10:56,431,573...56,444,847
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5320268|PMID:21642956)
BHF-UCL
RGD
PMID:21642956 GO_REF:0000024 MGI:5320268 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Nrxn1 neurexin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4366191|PMID:19822762), (MGI:5284755|PMID:19098102)
BHF-UCL
RGD
PMID:19098102 PMID:19822762 GO_REF:0000024 MGI:4366191 MGI:5284755 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Prkcz protein kinase C, zeta involved_in IDA PMID:11914719 UniProt PMID:11914719 RGD:8554098 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) RGD PMID:18082964 MGI:3772418 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP PMID:11239437 Alzheimers_University_of_Toronto PMID:11239437 RGD:8553497 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Reln reelin involved_in IEA
ISO
GO_REF:0000107
(MGI:3765383|PMID:17229826), (MGI:4442532|PMID:20357114), (MGI:5619457|PMID:21814183)
Ensembl
RGD
PMID:17229826 PMID:20357114 PMID:21814183 GO_REF:0000107 MGI:3765383 MGI:4442532 MGI:5619457 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:17220354 RGD:13524537 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:4887275|PMID:21262469)
ParkinsonsUK-UCL
RGD
PMID:21262469 GO_REF:0000024 MGI:4887275 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q99NE5|UniProtKB:Q9EQZ7 (MGI:4887275|PMID:21262469)
ParkinsonsUK-UCL
RGD
PMID:21262469 GO_REF:0000024 MGI:4887275 NCBI chr 7:78,091,998...78,594,164
Ensembl chr 7:78,092,037...78,594,138
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3775591|PMID:18272690)
BHF-UCL
RGD
PMID:18272690 GO_REF:0000024 MGI:3775591 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in ISS
ISO
IEA
PMID:21795692
(MGI:4948759|PMID:21423165), (MGI:5285139|PMID:21167025), (MGI:5320264|PMID:21795692)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:21167025 PMID:21423165 PMID:21795692, PMID:21795692 GO_REF:0000024 GO_REF:0000107 MGI:4948759 MGI:5285139 MGI:5320264, RGD:7349315 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Ssh1 slingshot protein phosphatase 1 IMP RGD PMID:20442266 RGD:11535133 NCBI chr12:48,403,184...48,447,964
Ensembl chr12:48,403,797...48,446,977
JBrowse link
G Stx1a syntaxin 1A involved_in ISO UniProtKB:O35526|UniProtKB:P61264 (MGI:5521403|PMID:24133272) RGD PMID:24133272 MGI:5521403 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stx1b syntaxin 1B involved_in ISS
ISO
GO_REF:0000024
UniProtKB:O35526 (MGI:5521403|PMID:24133272)
ParkinsonsUK-UCL
RGD
PMID:24133272 GO_REF:0000024 MGI:5521403 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
G Tbc1d24 TBC1 domain family, member 24 IMP RGD PMID:24469796 RGD:11537391 NCBI chr10:13,551,100...13,576,739
Ensembl chr10:13,551,100...13,558,384
JBrowse link
G Wnt7a Wnt family member 7A involved_in ISO (PMID:21670302)
UniProtKB:Q9WVB9 (MGI:5014434|PMID:21670302)
RGD PMID:21670302 MGI:5014434 NCBI chr 4:122,994,425...123,040,609
Ensembl chr 4:122,994,425...123,040,609
JBrowse link
positive regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in IEA
ISO
GO_REF:0000107
ComplexPortal:CPX-1070 (MGI:5902682|PMID:20395454)
Ensembl
RGD
PMID:20395454 GO_REF:0000107 MGI:5902682 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Afdn afadin, adherens junction formation factor IMP RGD PMID:22948147 RGD:13838731 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 involved_in IMP PMID:26595655 UniProt PMID:26595655 RGD:11085699 NCBI chr11:64,286,691...64,421,248
Ensembl chr11:64,286,694...64,421,248
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      signal transduction 6881
        positive regulation of signal transduction 1597
          positive regulation of excitatory postsynaptic potential 38
            positive regulation of mini excitatory postsynaptic potential 3
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18343
      cell communication 7539
        cell-cell signaling 1731
          synaptic signaling 916
            trans-synaptic signaling 889
              anterograde trans-synaptic signaling 880
                chemical synaptic transmission 880
                  chemical synaptic transmission, postsynaptic 126
                    excitatory postsynaptic potential 117
                      modulation of excitatory postsynaptic potential 57
                        positive regulation of excitatory postsynaptic potential 38
                          positive regulation of mini excitatory postsynaptic potential 3
paths to the root