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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of reactive oxygen species metabolic process
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Accession:GO:2000377 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
Synonyms:exact_synonym: regulation of ROS metabolic process;   regulation of reactive oxygen species metabolism


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regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member ISO protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ARF4 ADP ribosylation factor 4 involved_in IDA (PMID:19041174) UniProt PMID:19041174 NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220 		JBrowse link
G ATG5 autophagy related 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24185898) Ensembl
MGI		 PMID:24185898 GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G BCO2 beta-carotene oxygenase 2 involved_in IEA
ISS		 (PMID:21106934) Ensembl
BHF-UCL		 PMID:21106934 GO_REF:0000107 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G COQ7 coenzyme Q7, hydroxylase involved_in IMP
IBA		 (PMID:25961505) WB
GO_Central		 PMID:25961505 GO_REF:0000033 NCBI chr16:19,067,614...19,083,097
Ensembl chr16:19,067,614...19,080,095 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G EIF6 eukaryotic translation initiation factor 6 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:35,278,906...35,284,772
Ensembl chr20:35,278,907...35,284,985 		JBrowse link
G FOXM1 forkhead box M1 involved_in IMP (PMID:19696738) BHF-UCL PMID:19696738 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19896444) Ensembl
MGI		 PMID:19896444 GO_REF:0000107 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXO3 forkhead box O3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19896444) Ensembl
MGI		 PMID:19896444 GO_REF:0000107 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G IER3 immediate early response 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19096392) Ensembl
MGI		 PMID:19096392 GO_REF:0000107 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:24576675) ParkinsonsUK-UCL PMID:24576675 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:21052097) MGI PMID:21052097 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MIR21 microRNA 21 involved_in ISS
IDA		 (PMID:22836756) BHF-UCL PMID:22836756 GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MPV17 mitochondrial inner membrane protein MPV17 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:27,309,492...27,323,097
Ensembl chr 2:27,309,492...27,325,680 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:19457114 RGD:5508731 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IMP (PMID:21138942) ParkinsonsUK-UCL PMID:21138942 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IMP (PMID:22865452) UniProt PMID:22865452 NCBI chr  X:24,465,286...24,550,466
Ensembl chr  X:24,465,244...24,550,466 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in ISS
IBA
IEA		 BHF-UCL
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP
IGI		 (PMID:21138942)
(PMID:24475098)		 ParkinsonsUK-UCL PMID:21138942 PMID:24475098 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRCP prolylcarboxypeptidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21297000) Ensembl
MGI		 PMID:21297000 GO_REF:0000107 NCBI chr11:82,822,936...82,901,644
Ensembl chr11:82,822,936...82,970,584 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IMP (PMID:18541373) UniProt PMID:18541373 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21052097) Ensembl
MGI		 PMID:21052097 GO_REF:0000107 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RNF41 ring finger protein 41 involved_in IMP (PMID:18541373) UniProt PMID:18541373 NCBI chr12:56,202,179...56,221,969
Ensembl chr12:56,202,179...56,221,933 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G STK17A serine/threonine kinase 17a involved_in IMP (PMID:21489989) UniProt PMID:21489989 NCBI chr 7:43,583,108...43,627,379
Ensembl chr 7:43,582,758...43,650,713 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
IDA
ISO		 (PMID:22836756)
(PMID:21052097)		 Ensembl
BHF-UCL
MGI		 PMID:21052097 PMID:22836756 GO_REF:0000107 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TUSC2 tumor suppressor 2, mitochondrial calcium regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22513871) Ensembl
MGI		 PMID:22513871 GO_REF:0000107 NCBI chr 3:50,324,909...50,328,223
Ensembl chr 3:50,320,027...50,328,251 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNS cystinosin, lysosomal cystine transporter involved_in ISO
IEA		 RGD
Ensembl		 PMID:26482480 GO_REF:0000107 RGD:12910938 NCBI chr17:3,636,459...3,663,103
Ensembl chr17:3,636,459...3,663,103 		JBrowse link
G CYCS cytochrome c, somatic ISO RGD PMID:21410437 RGD:7349317 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISS (PMID:27525436) ARUK-UCL PMID:27525436 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G MPV17L MPV17 mitochondrial inner membrane protein like involved_in IDA (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr16:15,395,754...15,413,271
Ensembl chr16:15,395,754...15,413,271 		JBrowse link
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HP haptoglobin involved_in IDA (PMID:19740759) BHF-UCL PMID:19740759 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G MT3 metallothionein 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:12058024 GO_REF:0000107 RGD:625483 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088 		JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC6 histone deacetylase 6 involved_in IC (PMID:18606987) BHF-UCL PMID:18606987 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11991626 RGD:10003093 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:75,051,048...75,156,283
Ensembl chr  X:75,051,048...75,156,732 		JBrowse link
G ABCD1 ATP binding cassette subfamily D member 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:153,724,856...153,744,755
Ensembl chr  X:153,724,856...153,744,755 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,531,025...39,619,803
Ensembl chr12:39,550,033...39,619,803 		JBrowse link
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:32664470 GO_REF:0000107 RGD:329347825 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 ISO RGD PMID:22209705 RGD:13800744 NCBI chr17:48,892,787...48,895,871
Ensembl chr17:48,892,765...48,895,871 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator involved_in ISO
IEA		 RGD
Ensembl		 PMID:18292530 GO_REF:0000107 RGD:11341712 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G COA8 cytochrome c oxidase assembly factor 8 involved_in IMP (PMID:25175347) UniProt PMID:25175347 NCBI chr14:103,562,960...103,590,899
Ensembl chr14:103,562,960...103,607,523 		JBrowse link
G CTNS cystinosin, lysosomal cystine transporter involved_in ISO
IEA		 RGD
Ensembl		 PMID:26482480 GO_REF:0000107 RGD:12910938 NCBI chr17:3,636,459...3,663,103
Ensembl chr17:3,636,459...3,663,103 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:23041468 RGD:10401126 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587 		JBrowse link
G HBP1 HMG-box transcription factor 1 involved_in ISO (MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:5754467 NCBI chr 7:107,169,003...107,202,522
Ensembl chr 7:107,168,961...107,202,522 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:22547655 RGD:10402548 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G INS insulin involved_in IGI (PMID:19188609) ARUK-UCL PMID:19188609 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28483668 RGD:12910717 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR140 microRNA 140 ISO RGD PMID:32519270 RGD:329347827 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR181A1 microRNA 181a-1 involved_in IDA (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 1:198,859,044...198,859,153
Ensembl chr 1:198,859,044...198,859,153 		JBrowse link
G MIR181A2 microRNA 181a-2 involved_in IDA (PMID:23516523) ARUK-UCL PMID:23516523 NCBI chr 9:124,692,442...124,692,551
Ensembl chr 9:124,692,442...124,692,551 		JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR590 microRNA 590 involved_in IDA (PMID:26648441) BHF-UCL PMID:26648441 NCBI chr 7:74,191,198...74,191,294
Ensembl chr 7:74,191,198...74,191,294 		JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 ISO RGD PMID:26888427 RGD:11040458 NCBI chr11:78,068,297...78,079,862
Ensembl chr11:78,068,297...78,079,862 		JBrowse link
G PAGE4 PAGE family member 4 involved_in IDA (PMID:25374899) UniProt PMID:25374899 NCBI chr  X:49,829,260...49,834,264
Ensembl chr  X:49,793,653...49,834,264 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha acts_upstream_of IMP (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTGR1 prostaglandin reductase 1 ISO RGD PMID:9667737 RGD:401959219 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893 		JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:23422569 RGD:9585767 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in NAS (PMID:24252804) ParkinsonsUK-UCL PMID:24252804 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G TRAP1 TNF receptor associated protein 1 involved_in TAS (PMID:18221368) ParkinsonsUK-UCL PMID:18221368 NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553 		JBrowse link
negative regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG5 autophagy related 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7889565) Ensembl
MGI		 PMID:7889565 GO_REF:0000107 NCBI chr22:23,180,509...23,318,037
Ensembl chr22:23,179,704...23,318,037 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IMP (PMID:23415688) BHF-UCL PMID:23415688 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G CRYAB crystallin alpha B involved_in ISO
IEA		 RGD
Ensembl		 PMID:15358243 GO_REF:0000107 RGD:1598485 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:23608653 RGD:7364951 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:24190878 GO_REF:0000107 RGD:10449133 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) UniProt PMID:21052097 MGI:5315337 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MIR675 microRNA 675 acts_upstream_of IDA (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G MMP3 matrix metallopeptidase 3 involved_in IDA (PMID:20969476) ParkinsonsUK-UCL PMID:20969476 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5050076|PMID:17357786) UniProt PMID:17357786 MGI:5050076 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007 		JBrowse link
G PAX2 paired box 2 involved_in IDA (PMID:17357786) UniProt PMID:17357786 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IMP (PMID:18560593) ParkinsonsUK-UCL PMID:18560593 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PLIN5 perilipin 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,224 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IGI (PMID:18541373) ParkinsonsUK-UCL PMID:18541373 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:23397292 GO_REF:0000107 RGD:9586042 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SIRT5 sirtuin 5 involved_in IDA (PMID:24140062) UniProt PMID:24140062 NCBI chr 6:13,574,274...13,615,158
Ensembl chr 6:13,574,227...13,615,158 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in IDA (PMID:20066163) UniProt PMID:20066163 NCBI chr 6:10,396,677...10,419,659
Ensembl chr 6:10,393,186...10,419,659 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22044588) Ensembl
MGI		 PMID:22044588 GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (MGI:4868339|PMID:21048113) UniProt PMID:21048113 MGI:4868339 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11168643) Ensembl
MGI		 PMID:11168643 GO_REF:0000107 NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:24601882 RGD:39128160 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G CRP C-reactive protein ISO RGD PMID:9767445 RGD:9586000 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G PON3 paraoxonase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOXA1 dual oxidase maturation factor 1 involved_in IMP (PMID:22814254) UniProt PMID:22814254 NCBI chr15:45,117,366...45,129,879
Ensembl chr15:45,117,366...45,129,938 		JBrowse link
G DUOXA2 dual oxidase maturation factor 2 involved_in IDA
IMP		 (PMID:16651268)
(PMID:22814254)		 UniProt PMID:16651268 PMID:22814254 NCBI chr15:45,114,326...45,118,421
Ensembl chr15:45,114,326...45,118,421 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:27279484 RGD:151347625 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20529999 GO_REF:0000107 RGD:27095884 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G ZNF205 zinc finger protein 205 involved_in IMP (PMID:22306510) BHF-UCL PMID:22306510 NCBI chr16:3,112,586...3,120,517
Ensembl chr16:3,112,560...3,120,517 		JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NNT nicotinamide nucleotide transhydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:24722990 GO_REF:0000107 RGD:13513981 NCBI chr 5:43,602,675...43,707,396
Ensembl chr 5:43,602,692...43,707,405 		JBrowse link
G SNCA synuclein alpha involved_in IDA (PMID:23507046) ParkinsonsUK-UCL PMID:23507046 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 involved_in ISO
IEA		 RGD
Ensembl		 PMID:28386847 GO_REF:0000107 RGD:329337357 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IMP (PMID:26838550) UniProt PMID:26838550 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15450084 RGD:2313867 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16522634) Ensembl
MGI		 PMID:16522634 GO_REF:0000107 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G FOXO3 forkhead box O3 involved_in ISO
IEA		 RGD
Ensembl		 PMID:24278276 GO_REF:0000107 RGD:10402204 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756 		JBrowse link
G HDAC4 histone deacetylase 4 ISO RGD PMID:24166750 RGD:9681442 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:24073824 RGD:10402792 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR24-1 microRNA 24-1 involved_in IDA (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr 9:95,086,021...95,086,088
Ensembl chr 9:95,086,021...95,086,088 		JBrowse link
G MIR24-2 microRNA 24-2 involved_in IDA (PMID:21788589) BHF-UCL PMID:21788589 NCBI chr19:13,836,287...13,836,359
Ensembl chr19:13,836,287...13,836,359 		JBrowse link
G MIR675 microRNA 675 acts_upstream_of IDA (PMID:31574452) ARUK-UCL PMID:31574452 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO RGD PMID:21712532 RGD:9590189 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22555455) Ensembl
MGI		 PMID:22555455 GO_REF:0000107 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of
involved_in		 ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G RAB27A RAB27A, member RAS oncogene family involved_in IMP (PMID:24404184) UniProt PMID:24404184 NCBI chr15:55,202,966...55,289,813
Ensembl chr15:55,202,966...55,319,113 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
positive regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IC (PMID:15380922) BHF-UCL PMID:15380922 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:19885844 RGD:7244243 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGT angiotensinogen involved_in TAS (PMID:17906677) BHF-UCL PMID:17906677 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in TAS (PMID:17159080) BHF-UCL PMID:17159080 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 involved_in IDA (PMID:19442656) UniProt PMID:19442656 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IDA (PMID:19442656) UniProt PMID:19442656 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G CBR1 carbonyl reductase 1 involved_in IDA (PMID:19442656) UniProt PMID:19442656 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IMP
IEA		 (PMID:20160708) BHF-UCL
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20439821 GO_REF:0000107 RGD:7829726 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DCXR dicarbonyl and L-xylulose reductase involved_in IDA (PMID:19442656) UniProt PMID:19442656 NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709 		JBrowse link
G DHRS4 dehydrogenase/reductase 4 involved_in IDA (PMID:19442656) UniProt PMID:19442656 NCBI chr14:23,953,770...23,969,279
Ensembl chr14:23,953,734...23,969,279 		JBrowse link
G DUOXA1 dual oxidase maturation factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20233719) Ensembl
MGI		 PMID:20233719 GO_REF:0000107 NCBI chr15:45,117,366...45,129,879
Ensembl chr15:45,117,366...45,129,938 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A ISO RGD PMID:20930373 RGD:10395362 NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IDA (PMID:17275676) UniProt PMID:17275676 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha involved_in IMP (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IMP (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:30574656 RGD:126781752 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEP leptin involved_in ISO
IEA		 RGD
Ensembl		 PMID:20738325 GO_REF:0000107 RGD:8693628 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in IMP (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:16254042 RGD:1581408 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:15848200 RGD:2324674 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NOX5 NADPH oxidase 5 involved_in IDA (PMID:17275676) UniProt PMID:17275676 NCBI chr15:68,930,525...69,062,762
Ensembl chr15:69,014,695...69,062,762
Ensembl chr15:69,014,695...69,062,762 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 ISO RGD PMID:23554738 RGD:11073697 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IDA (PMID:20969476) ParkinsonsUK-UCL PMID:20969476 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IDA (PMID:19019919) UniProt PMID:19019919 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IMP (PMID:20165904) BHF-UCL PMID:20165904 NCBI chr 2:229,023,973...229,271,287
Ensembl chr 2:228,850,526...229,271,287 		JBrowse link
G PLAU plasminogen activator, urokinase ISO RGD PMID:16456094 RGD:6484217 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in ISO
IEA		 RGD
Ensembl		 PMID:15158121 GO_REF:0000107 RGD:1642626 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in TAS (PMID:17979836) BHF-UCL PMID:17979836 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19498109) Ensembl
MGI		 PMID:19498109 GO_REF:0000107 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RNF41 ring finger protein 41 involved_in IMP (PMID:18541373) ParkinsonsUK-UCL PMID:18541373 NCBI chr12:56,202,179...56,221,969
Ensembl chr12:56,202,179...56,221,933 		JBrowse link
G ROMO1 reactive oxygen species modulator 1 involved_in IDA (PMID:16842742) UniProt PMID:16842742 NCBI chr20:35,699,405...35,700,980
Ensembl chr20:35,699,272...35,700,984 		JBrowse link
G SIRPA signal regulatory protein alpha involved_in IDA (PMID:24511121) UniProt PMID:24511121 NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592 		JBrowse link
G SPESP1-NOX5 SPESP1-NOX5 readthrough involved_in IDA (PMID:17275676) UniProt PMID:17275676
G TGFBR2 transforming growth factor beta receptor 2 involved_in IMP (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G THBS1 thrombospondin 1 involved_in IDA (PMID:18757424), (PMID:24511121) UniProt PMID:18757424 PMID:24511121 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TP53 tumor protein p53 involved_in IMP (PMID:20160708) BHF-UCL PMID:20160708 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSPO translocator protein involved_in ISO
IEA		 RGD
Ensembl		 PMID:12437594 GO_REF:0000107 RGD:2317161 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G XDH xanthine dehydrogenase involved_in IDA (PMID:18386220) UniProt PMID:18386220 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IDA (PMID:22739135) BHF-UCL PMID:22739135 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO
TAS		 (PMID:19193863) RGD
BHF-UCL		 PMID:19193863 PMID:21376054 RGD:5129173 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:21076237 RGD:5129195 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G APP amyloid beta precursor protein involved_in IGI (PMID:11316806) ARUK-UCL PMID:11316806 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G CD177 CD177 molecule involved_in IGI (PMID:21193407) UniProt PMID:21193407 NCBI chr19:43,353,686...43,366,081
Ensembl chr19:43,353,686...43,363,172 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IDA (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CRP C-reactive protein involved_in IDA (PMID:24141169) AgBase PMID:24141169 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 involved_in ISO (MGI:5586806|PMID:10725737) UniProt PMID:10725737 MGI:5586806 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:15036821 RGD:8693734 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:22966991 GO_REF:0000107 RGD:7204494 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ELAVL1 ELAV like RNA binding protein 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:26682942 GO_REF:0000107 RGD:329961560 NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:11714832) UniProt PMID:11714832 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr19:51,761,180...51,770,531
Ensembl chr19:51,752,026...51,770,531 		JBrowse link
G GNAI2 G protein subunit alpha i2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:27912212 GO_REF:0000107 RGD:13507308 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:24935944 GO_REF:0000107 RGD:14985214 NCBI chr12:110,648,686...110,704,952
Ensembl chr12:110,627,841...110,704,950 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:19497959 RGD:4889403 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G ITGAM integrin subunit alpha M involved_in ISS
IGI		 (PMID:21193407) ARUK-UCL
UniProt		 PMID:21193407 GO_REF:0000024 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB2 integrin subunit beta 2 involved_in IGI
NAS		 (PMID:21193407)
(PMID:18981141)		 UniProt
ARUK-UCL		 PMID:18981141 PMID:21193407 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G MAPT microtubule associated protein tau involved_in IMP (PMID:22920254) ParkinsonsUK-UCL PMID:22920254 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:24294978 PMID:26682942 RGD:329955573 RGD:329961560 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 involved_in ISO (PMID:24141169) AgBase PMID:24141169 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138 		JBrowse link
G PRKCD protein kinase C delta involved_in IMP (PMID:19801500) UniProt PMID:19801500 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCE protein kinase C epsilon acts_upstream_of TAS (PMID:19193863) BHF-UCL PMID:19193863 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in IDA (PMID:18219391) UniProt PMID:18219391 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IMP (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IDA (PMID:22073128) BHF-UCL PMID:22073128 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSR insulin receptor ISO in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G NOXA1 NADPH oxidase activator 1 involved_in IMP (PMID:16636067) BHF-UCL PMID:16636067 NCBI chr 9:137,423,393...137,434,406
Ensembl chr 9:137,423,350...137,434,406 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 involved_in TAS (PMID:16636067) BHF-UCL PMID:16636067 NCBI chr16:1,978,917...1,981,469
Ensembl chr16:1,978,917...1,984,192 		JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PRDX2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17325201) Ensembl
MGI		 PMID:17325201 GO_REF:0000107 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in TAS (PMID:16636067) BHF-UCL PMID:16636067 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAC2 Rac family small GTPase 2 involved_in TAS (PMID:16636067) BHF-UCL PMID:16636067 NCBI chr22:37,225,270...37,244,269
Ensembl chr22:37,225,270...37,259,594 		JBrowse link
regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IMP (PMID:26210919) UniProt PMID:26210919 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G CCN6 cellular communication network factor 6 involved_in IMP (PMID:27252383) UniProt PMID:27252383 NCBI chr 6:112,052,813...112,069,686
Ensembl chr 6:112,054,075...112,069,686 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in IDA
IEA		 (PMID:30478045) UniProt
Ensembl		 PMID:30478045 GO_REF:0000107 NCBI chr12:110,648,686...110,704,952
Ensembl chr12:110,627,841...110,704,950 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO RGD PMID:27279484 RGD:151347625 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in IDA
IBA
IEA		 (PMID:28779020) UniProt
GO_Central
Ensembl		 PMID:28779020 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746 		JBrowse link
G SLC25A33 solute carrier family 25 member 33 involved_in IMP (PMID:20453889) UniProt PMID:20453889 NCBI chr 1:9,539,465...9,585,173
Ensembl chr 1:9,539,465...9,585,173 		JBrowse link
G SNCA synuclein alpha involved_in TAS (PMID:24252804) ParkinsonsUK-UCL PMID:24252804 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
G UCP1 uncoupling protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP7 bone morphogenetic protein 7 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G DHFR dihydrofolate reductase involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983 		JBrowse link
G DHFRP1 dihydrofolate reductase pseudogene 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr18:26,167,862...26,171,357
Ensembl chr18:26,170,726...26,171,284 		JBrowse link
G FBLN5 fibulin 5 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,411...91,947,987 		JBrowse link
G GCH1 GTP cyclohydrolase 1 involved_in IMP (PMID:19666465) BHF-UCL PMID:19666465 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYK spleen associated tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BST1 bone marrow stromal cell antigen 1 involved_in TAS (PMID:23576305) ParkinsonsUK-UCL PMID:23576305 NCBI chr 4:15,703,065...15,774,173
Ensembl chr 4:15,703,065...15,738,313 		JBrowse link
G MIR27B microRNA 27b involved_in IGI (PMID:24177325) BHF-UCL PMID:24177325 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G SHC1 SHC adaptor protein 1 involved_in IGI (PMID:24177325) BHF-UCL PMID:24177325 NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    metabolic process 13065
      regulation of metabolic process 7698
        regulation of cellular metabolic process 6923
          regulation of reactive oxygen species metabolic process 194
            negative regulation of reactive oxygen species metabolic process + 68
            positive regulation of reactive oxygen species metabolic process + 92
            regulation of hydrogen peroxide metabolic process + 25
            regulation of reactive oxygen species biosynthetic process + 68
            regulation of superoxide metabolic process + 41
Path 2
Term Annotations click to browse term
  biological_process 19770
    biological regulation 13512
      regulation of biological process 13114
        regulation of metabolic process 7698
          regulation of cellular metabolic process 6923
            regulation of reactive oxygen species metabolic process 194
              negative regulation of reactive oxygen species metabolic process + 68
              positive regulation of reactive oxygen species metabolic process + 92
              regulation of hydrogen peroxide metabolic process + 25
              regulation of reactive oxygen species biosynthetic process + 68
              regulation of superoxide metabolic process + 41
paths to the root