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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ceramide biosynthetic process
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Accession:GO:2000303 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
Synonyms:exact_synonym: regulation of ceramide anabolism;   regulation of ceramide biosynthesis;   regulation of ceramide formation;   regulation of ceramide synthesis


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regulation of ceramide biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO MGI:MGI:1913862 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO MGI:MGI:2137691|MGI:MGI:2181669|MGI:MGI:6382064 (MGI:MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:MGI:6393026 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Samd8 sterile alpha motif domain containing 8 ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,685,504...2,731,062
Ensembl chr15:2,685,511...2,731,462
JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO
IBA
(PMID:25691431)
PMID:21873635
RGD PMID:25691431, PMID:21873635 RGD:13792537 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 ISO
IBA
(PMID:25691431)
PMID:21873635
RGD PMID:25691431, PMID:21873635 RGD:13792537 NCBI chr 7:3,242,991...3,246,085
Ensembl chr 7:3,242,991...3,246,071
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO
IBA
IEA
(MGI:MGI:5638294|PMID:25691431)
PMID:21873635
GO_REF:0000107
(PMID:25691431)
RGD
Ensembl
PMID:25691431, PMID:21873635 GO_REF:0000107, MGI:MGI:5638294, RGD:13792537 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Sphk1 sphingosine kinase 1 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:6294167|PMID:16118219)
(PMID:16118219)
UniProt
Ensembl
RGD
PMID:16118219 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6294167 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 ISO
IEA
(MGI:MGI:3849354|PMID:19364818)
GO_REF:0000107
RGD
Ensembl
PMID:19364818 GO_REF:0000107, MGI:MGI:3849354 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 ISS
ISO
GO_REF:0000024
(MGI:MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024, MGI:MGI:4947032 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Pla2g6 phospholipase A2 group VI IDA RGD PMID:18936091 RGD:6482750 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Prkcd protein kinase C, delta ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Sirt3 sirtuin 3 ISO (MGI:MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:MGI:5755322 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sphk2 sphingosine kinase 2 ISO (PMID:16118219)
(MGI:MGI:6294167|PMID:16118219)
RGD PMID:16118219 MGI:MGI:6294167 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      regulation of cellular process 12561
        regulation of cellular component biogenesis 1037
          regulation of sphingolipid biosynthetic process 14
            regulation of ceramide biosynthetic process 12
              negative regulation of ceramide biosynthetic process + 4
              positive regulation of ceramide biosynthetic process + 7
              regulation of glucosylceramide biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      primary metabolic process 10941
        lipid metabolic process 1374
          cellular lipid metabolic process 1023
            membrane lipid metabolic process 191
              membrane lipid biosynthetic process 129
                sphingolipid biosynthetic process 89
                  regulation of sphingolipid biosynthetic process 14
                    regulation of ceramide biosynthetic process 12
                      negative regulation of ceramide biosynthetic process + 4
                      positive regulation of ceramide biosynthetic process + 7
                      regulation of glucosylceramide biosynthetic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.