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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of ceramide biosynthetic process
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Accession:GO:2000303 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
Synonyms:exact_synonym: regulation of ceramide anabolism;   regulation of ceramide biosynthesis;   regulation of ceramide formation;   regulation of ceramide synthesis


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regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068509 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr17:11,942,344...11,942,538 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
ISS		 (PMID:17303575)
GO_REF:0000024		 RGD
UniProt		 PMID:17303575 GO_REF:0000024 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25691431)
(MGI:5638294|PMID:25691431)		 Ensembl
RGD		 PMID:25691431 GO_REF:0000107 MGI:5638294 NCBI chr10:83,590,052...83,598,620
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)		 UniProt
Ensembl
RGD		 PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (MGI:3849354|PMID:19364818) RGD PMID:19364818 MGI:3849354 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:18936091 PMID:21873635 RGD:6482750, RGD:13792537 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:5755322 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 RGD PMID:16118219 MGI:6294167 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      nitrogen compound metabolic process 8214
        amide metabolic process 1648
          regulation of amide metabolic process 586
            regulation of ceramide biosynthetic process 13
              negative regulation of ceramide biosynthetic process + 4
              positive regulation of ceramide biosynthetic process + 7
              regulation of glucosylceramide biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    metabolic process 12010
      primary metabolic process 8886
        lipid metabolic process 1448
          cellular lipid metabolic process 1051
            membrane lipid metabolic process 202
              membrane lipid biosynthetic process 142
                sphingolipid biosynthetic process 102
                  regulation of sphingolipid biosynthetic process 15
                    regulation of ceramide biosynthetic process 13
                      negative regulation of ceramide biosynthetic process + 4
                      positive regulation of ceramide biosynthetic process + 7
                      regulation of glucosylceramide biosynthetic process + 0
paths to the root