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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA biosynthetic process
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Accession:GO:2000278 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
Synonyms:exact_synonym: regulation of DNA anabolism;   regulation of DNA biosynthesis;   regulation of DNA formation;   regulation of DNA synthesis


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regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:3617096|PMID:11981756) MGI PMID:11981756 MGI:3617096 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G PDGFA platelet derived growth factor subunit A NOT|involved_in IDA (PMID:11788434), (PMID:19019919) UniProt PMID:11788434 PMID:19019919 NCBI chr 7:497,245...520,668
Ensembl chr 7:497,258...520,296
JBrowse link
G SH2B1 SH2B adaptor protein 1 involved_in ISO (MGI:5009204|PMID:10644978) UniProt PMID:10644978 MGI:5009204 NCBI chr16:28,846,606...28,874,205
Ensembl chr16:28,846,600...28,874,212
JBrowse link
G TFDP1 transcription factor Dp-1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3525422|PMID:15448153) Ensembl
MGI
PMID:15448153 GO_REF:0000107 MGI:3525422 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473
JBrowse link
G TOM1L1 target of myb1 like 1 membrane trafficking protein NOT|involved_in IDA (PMID:16479011) UniProt PMID:16479011 NCBI chr17:54,900,807...54,961,967
Ensembl chr17:54,899,387...54,961,956
JBrowse link
negative regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in IMP (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IDA (PMID:12070119) UniProt PMID:12070119 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G ANKRD1 ankyrin repeat domain 1 involved_in IMP (PMID:11139470) BHF-UCL PMID:11139470 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IMP (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IMP (PMID:11595739) UniProt PMID:11595739 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CHEK1 checkpoint kinase 1 ISO RGD PMID:12429946 RGD:2316115 NCBI chr11:125,624,910...125,676,255
Ensembl chr11:125,625,163...125,676,255
JBrowse link
G DACH1 dachshund family transcription factor 1 involved_in IDA (PMID:16980615) CACAO PMID:16980615 NCBI chr13:71,437,966...71,868,068
Ensembl chr13:71,437,966...71,867,204
JBrowse link
G DNAJC2 DnaJ heat shock protein family (Hsp40) member C2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:76992|PMID:7559602) Ensembl
MGI
PMID:7559602 GO_REF:0000107 MGI:76992 NCBI chr 7:103,312,289...103,344,790
Ensembl chr 7:103,312,289...103,344,830
JBrowse link
G DUSP1 dual specificity phosphatase 1 involved_in IEA
ISO
Ensembl
RGD
PMID:10446064 GO_REF:0000107 RGD:7771571 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G GDF2 growth differentiation factor 2 involved_in IDA (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in IEA
ISO
Ensembl
RGD
PMID:14702389 GO_REF:0000107 RGD:8662403 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 involved_in IEA
ISO
Ensembl
RGD
PMID:23271285 GO_REF:0000107 RGD:9831181 NCBI chr 1:215,002,920...215,237,093
Ensembl chr 1:215,005,775...215,237,090
JBrowse link
G NIBAN2 niban apoptosis regulator 2 involved_in IDA (PMID:14602737), (PMID:17569660), (PMID:20032057) UniProt PMID:14602737 PMID:17569660 PMID:20032057 NCBI chr 9:127,505,339...127,579,031
Ensembl chr 9:127,505,339...127,578,989
JBrowse link
G NPPC natriuretic peptide C involved_in IEA
ISO
Ensembl
RGD
PMID:12746286 GO_REF:0000107 RGD:1580115 NCBI chr 2:231,921,809...231,926,405
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G RGN regucalcin involved_in IEA
ISO
Ensembl
RGD
PMID:11500948 GO_REF:0000107 RGD:9590199 NCBI chr  X:47,078,414...47,093,313
Ensembl chr  X:47,078,355...47,093,314
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:11502571 RGD:70312 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS1 ceramide synthase 1 involved_in IDA (PMID:17548428) UniProt PMID:17548428 NCBI chr19:18,868,545...18,896,982
Ensembl chr19:18,868,545...18,896,727
JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit NOT|involved_in IDA (PMID:18812185) BHF-UCL PMID:18812185 NCBI chr16:13,920,137...13,952,348
Ensembl chr16:13,920,138...13,952,348
JBrowse link
G MCRS1 microspherule protein 1 involved_in IDA (PMID:15044100) BHF-UCL PMID:15044100 NCBI chr12:49,558,299...49,568,233
Ensembl chr12:49,556,544...49,568,145
JBrowse link
G MEN1 menin 1 involved_in IMP (PMID:12837246) UniProt PMID:12837246 NCBI chr11:64,803,514...64,811,294
Ensembl chr11:64,803,510...64,811,294
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in IDA (PMID:16522649) HGNC-UCL PMID:16522649 NCBI chr15:64,815,632...64,827,173
Ensembl chr15:64,815,632...64,825,668
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in IMP
IDA
NAS
(PMID:11701125), (PMID:21119197)
(PMID:26194824)
BHF-UCL PMID:11701125 PMID:21119197 PMID:26194824 NCBI chr 8:10,764,961...10,839,875
Ensembl chr 8:10,725,399...10,839,847
Ensembl chr 8:10,725,399...10,839,847
JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:19567472) UniProt PMID:19567472 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G POT1 protection of telomeres 1 involved_in IBA
IDA
(PMID:21873635)
(PMID:15632080)
GO_Central
BHF-UCL
PMID:15632080 PMID:21873635 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in IEA
ISO
Ensembl
RGD
PMID:16556873 GO_REF:0000107 RGD:1580657 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IEA GOC GO_REF:0000108 NCBI chr17:75,979,240...76,000,586
Ensembl chr17:75,979,240...76,000,586
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in IGI (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr 8:73,008,856...73,048,123
Ensembl chr 8:73,008,856...73,048,123
JBrowse link
G TP53 tumor protein p53 involved_in IDA (PMID:10597287) BHF-UCL PMID:10597287 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
negative regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in IMP (PMID:24528514) BHF-UCL PMID:24528514 NCBI chr 3:51,942,290...51,948,867
Ensembl chr 3:51,942,345...51,948,867
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IBA
IGI
IMP
TAS
(PMID:21873635)
(PMID:15181449)
(PMID:15380063)
(PMID:17237768), (PMID:25467444)
GO_Central
BHF-UCL
PMID:15181449 PMID:15380063 PMID:17237768 PMID:21873635 PMID:25467444 NCBI chr16:67,657,512...67,660,832
Ensembl chr16:67,657,512...67,660,815
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in IDA (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:8,224,815...8,248,079
Ensembl chr17:8,224,815...8,248,056
JBrowse link
G DCP2 decapping mRNA 2 involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 5:112,976,702...113,022,195
Ensembl chr 5:112,976,702...113,022,195
JBrowse link
G EXOSC10 exosome component 10 involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 1:11,066,613...11,099,869
Ensembl chr 1:11,066,618...11,099,869
JBrowse link
G GNL3L G protein nucleolar 3 like involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:54,530,219...54,567,289
Ensembl chr  X:54,530,183...54,621,521
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in IMP (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr14:21,209,147...21,269,442
Ensembl chr14:21,209,136...21,269,494
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IBA
IMP
(PMID:21873635)
(PMID:18082603)
GO_Central
BHF-UCL
PMID:18082603 PMID:21873635 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr11:34,105,629...34,146,908
Ensembl chr11:34,105,617...34,147,670
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in IDA (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr15:64,815,632...64,827,173
Ensembl chr15:64,815,632...64,825,668
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in IDA
IMP
(PMID:11701125)
(PMID:21119197)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr 8:10,764,961...10,839,875
Ensembl chr 8:10,725,399...10,839,847
Ensembl chr 8:10,725,399...10,839,847
JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:19567472) UniProt PMID:19567472 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G POT1 protection of telomeres 1 involved_in TAS
IGI
(PMID:17237768)
(PMID:15181449)
BHF-UCL PMID:15181449 PMID:17237768 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STN1 STN1 subunit of CST complex involved_in IDA (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr10:103,877,569...103,918,184
Ensembl chr10:103,877,569...103,918,184
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IDA
IBA
(PMID:22763445)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635 PMID:22763445 NCBI chr17:75,979,240...76,000,586
Ensembl chr17:75,979,240...76,000,586
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr16:50,152,911...50,235,310
Ensembl chr16:50,152,911...50,235,310
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in TAS
IGI
(PMID:16275645), (PMID:24389012)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:16275645 PMID:24389012 NCBI chr 8:73,008,856...73,048,123
Ensembl chr 8:73,008,856...73,048,123
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IDA
IC
IMP
(PMID:17055345)
(PMID:15657433)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:15657433 PMID:17055345 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IGI
IMP
(PMID:10581025)
(PMID:15133513)
BHF-UCL PMID:10581025 PMID:15133513 NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,239,643...24,242,674
JBrowse link
G XRN1 5'-3' exoribonuclease 1 involved_in IC (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 3:142,306,610...142,448,062
Ensembl chr 3:142,306,607...142,448,062
JBrowse link
positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA
ISO
Ensembl
RGD
PMID:19254952 GO_REF:0000107 RGD:5509898 NCBI chr17:4,710,619...4,721,500
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G C3AR1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16005543 RGD:5131269 NCBI chr 7:30,649,406...30,700,103
Ensembl chr 7:30,651,942...30,700,129
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:20439821 RGD:7829726 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G DDX39B DExD-box helicase 39B involved_in IEA
ISO
Ensembl
RGD
PMID:22446327 GO_REF:0000107 RGD:10401140 NCBI chr 6:31,530,226...31,542,003
Ensembl chr 6:31,530,219...31,542,448
JBrowse link
G EGF epidermal growth factor ISO RGD PMID:3093142 RGD:10395243 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G FGF2 fibroblast growth factor 2 involved_in IGI
IDA
(PMID:16774925) UniProt PMID:16774925 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IMP (PMID:21653700) UniProt PMID:21653700 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144
JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:16937468 RGD:9685728 NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:12721208 RGD:10045365 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HGF hepatocyte growth factor involved_in IDA (PMID:2531289) UniProt PMID:2531289 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IMP (PMID:9924025) UniProt PMID:9924025 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) UniProt PMID:17942966 MGI:5009390 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in IEA
ISO
Ensembl
RGD
PMID:12890786 GO_REF:0000107 RGD:7775030 NCBI chr  X:110,944,324...111,227,361
Ensembl chr  X:110,944,285...111,227,361
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IDA (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919) UniProt PMID:10644978 PMID:10734101 PMID:11788434 PMID:12070119 PMID:16530387 PMID:17942966 PMID:19019919 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PRKD2 protein kinase D2 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA
ISO
Ensembl
RGD
PMID:21451101 GO_REF:0000107 RGD:10041071 NCBI chr 8:27,311,478...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G RGCC regulator of cell cycle involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr13:41,457,411...41,470,876
Ensembl chr13:41,457,550...41,470,871
JBrowse link
G SMOC2 SPARC related modular calcium binding 2 involved_in IGI
IDA
(PMID:16774925) UniProt PMID:16774925 NCBI chr 6:168,441,153...168,667,992
Ensembl chr 6:168,441,151...168,673,445
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9395232 RGD:14696805 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IDA
IGI
(PMID:16774925) UniProt PMID:16774925 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr16:69,118,010...69,132,588
Ensembl chr16:69,118,010...69,132,588
JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 8:119,833,960...119,855,920
Ensembl chr 8:119,833,976...119,855,894
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810
JBrowse link
G PCNA proliferating cell nuclear antigen involved_in IMP (PMID:11595739) UniProt PMID:11595739 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in IDA (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr17:64,477,785...64,497,054
Ensembl chr17:64,477,785...64,497,054
JBrowse link
G RFC2 replication factor C subunit 2 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 7:74,231,502...74,254,452
Ensembl chr 7:74,231,499...74,254,458
JBrowse link
G RFC3 replication factor C subunit 3 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr13:33,818,075...33,973,946
Ensembl chr13:33,818,069...33,966,558
JBrowse link
G RFC4 replication factor C subunit 4 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr 3:186,789,900...186,806,482
Ensembl chr 3:186,789,880...186,807,058
JBrowse link
G RFC5 replication factor C subunit 5 involved_in IDA (PMID:12930902) UniProt PMID:12930902 NCBI chr12:118,016,661...118,033,564
Ensembl chr12:118,013,588...118,033,130
JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IEA
IBA
IDA
(PMID:21873635)
(PMID:17237768)
InterPro
GO_Central
BHF-UCL
PMID:17237768 PMID:21873635 GO_REF:0000002 NCBI chr16:67,657,512...67,660,832
Ensembl chr16:67,657,512...67,660,815
JBrowse link
G AURKB aurora kinase B involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:8,204,731...8,210,767
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISS ARUK-UCL GO_REF:0000024 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:25467444)
(MGI:3047190|PMID:15240872)
BHF-UCL
MGI
PMID:15240872 PMID:25467444 MGI:3047190 NCBI chr  X:154,762,864...154,777,689
Ensembl chr  X:154,762,742...154,777,689
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IDA (PMID:16545136) BHF-UCL PMID:16545136 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
JBrowse link
G GRHL2 grainyhead like transcription factor 2 involved_in IMP (PMID:19015635), (PMID:20938050) UniProt PMID:19015635 PMID:20938050 NCBI chr 8:101,492,439...101,678,104
Ensembl chr 8:101,492,439...101,669,726
JBrowse link
G HMBOX1 homeobox containing 1 involved_in IDA
IMP
(PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,890,394...29,064,945
Ensembl chr 8:28,890,395...29,064,764
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IDA (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IDA (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G KLF4 Kruppel like factor 4 involved_in IDA (PMID:20629177) BHF-UCL PMID:20629177 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,903,785...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:160,991,521...161,117,385
Ensembl chr 6:160,991,727...161,117,385
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in IMP
IDA
(PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:143,716,305...143,722,458
Ensembl chr 8:143,716,340...143,722,458
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:111,842,228...111,902,222
Ensembl chr12:111,842,228...111,902,222
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in IMP (PMID:27510903) BHF-UCL PMID:27510903 NCBI chr 4:163,109,133...163,166,910
Ensembl chr 4:163,110,073...163,166,890
JBrowse link
G NEK2 NIMA related kinase 2 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630
JBrowse link
G NEK7 NIMA related kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420
JBrowse link
G NVL nuclear VCP like involved_in IBA
IMP
(PMID:21873635)
(PMID:22226966)
GO_Central
UniProt
PMID:21873635 PMID:22226966 NCBI chr 1:224,227,345...224,330,187
Ensembl chr 1:224,227,334...224,330,189
JBrowse link
G PARM1 prostate androgen-regulated mucin-like protein 1 involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr 4:74,933,116...75,050,113
Ensembl chr 4:74,933,095...75,050,115
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in IMP (PMID:26482878) BHF-UCL PMID:26482878 NCBI chr16:14,435,701...14,630,286
Ensembl chr16:14,435,700...14,632,728
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351
JBrowse link
G POT1 protection of telomeres 1 involved_in IMP
IDA
(PMID:15181449)
(PMID:16043710), (PMID:17237768)
BHF-UCL PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G PRKCQ protein kinase C theta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,393,038...6,580,646
Ensembl chr10:6,427,143...6,580,301
JBrowse link
G PTGES3 prostaglandin E synthase 3 involved_in IMP
IDA
(PMID:19740745)
(PMID:10197982), (PMID:19740745)
BHF-UCL PMID:10197982 PMID:19740745 NCBI chr12:56,663,349...56,689,575
Ensembl chr12:56,663,341...56,688,408
JBrowse link
G TCP1 t-complex 1 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TNKS tankyrase involved_in IDA (PMID:12782650) BHF-UCL PMID:12782650 NCBI chr 8:9,555,230...9,782,346
Ensembl chr 8:9,555,912...9,782,346
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IDA
IMP
(PMID:19179534), (PMID:23685356), (PMID:29804836)
(PMID:23685356), (PMID:25467444)
BHF-UCL PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in TAS (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link
positive regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 7:26,189,920...26,200,775
Ensembl chr 7:26,171,151...26,201,529
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IDA (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:67,657,512...67,660,832
Ensembl chr16:67,657,512...67,660,815
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 3:142,449,235...142,578,793
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G AURKB aurora kinase B involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:8,204,731...8,210,767
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 1:156,308,968...156,338,292
Ensembl chr 1:156,308,968...156,367,873
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:56,051,765...56,063,989
Ensembl chr 7:56,051,685...56,063,989
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 2:73,233,425...73,253,008
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr21:29,056,326...29,073,648
Ensembl chr21:29,055,805...29,073,797
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISS ARUK-UCL GO_REF:0000024 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047190|PMID:15240872) Ensembl
MGI
PMID:15240872 GO_REF:0000107 MGI:3047190 NCBI chr  X:154,762,864...154,777,689
Ensembl chr  X:154,762,742...154,777,689
JBrowse link
G FBXO4 F-box protein 4 involved_in IC
IMP
(PMID:24389012)
(PMID:16275645)
BHF-UCL PMID:16275645 PMID:24389012 NCBI chr 5:41,918,061...42,040,230
Ensembl chr 5:41,925,254...41,941,743
JBrowse link
G HMBOX1 homeobox containing 1 involved_in IMP
IDA
(PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,890,394...29,064,945
Ensembl chr 8:28,890,395...29,064,764
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in IDA (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,903,785...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:160,991,521...161,117,385
Ensembl chr 6:160,991,727...161,117,385
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in IDA
IMP
(PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:143,716,305...143,722,458
Ensembl chr 8:143,716,340...143,722,458
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:111,842,228...111,902,222
Ensembl chr12:111,842,228...111,902,222
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in TAS (PMID:22527283) BHF-UCL PMID:22527283 NCBI chr 4:163,109,133...163,166,910
Ensembl chr 4:163,110,073...163,166,890
JBrowse link
G NEK2 NIMA related kinase 2 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630
JBrowse link
G NEK7 NIMA related kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in IMP (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chr16:14,435,701...14,630,286
Ensembl chr16:14,435,700...14,632,728
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351
JBrowse link
G POT1 protection of telomeres 1 involved_in IMP
IDA
(PMID:12768206), (PMID:12781132)
(PMID:17237768)
BHF-UCL PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G PRKCQ protein kinase C theta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,393,038...6,580,646
Ensembl chr10:6,427,143...6,580,301
JBrowse link
G TCP1 t-complex 1 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TERC telomerase RNA component acts_upstream_of_or_within ISO (MGI:3774867|PMID:17982445) MGI PMID:17982445 MGI:3774867 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047
JBrowse link
G TNKS tankyrase involved_in IDA
IEA
IMP
(PMID:12782650), (PMID:18221737)
(PMID:11739745)
BHF-UCL
InterPro
PMID:11739745 PMID:12782650 PMID:18221737 GO_REF:0000002 NCBI chr 8:9,555,230...9,782,346
Ensembl chr 8:9,555,912...9,782,346
JBrowse link
G TNKS2 tankyrase 2 involved_in IC (PMID:11739745) BHF-UCL PMID:11739745 NCBI chr10:91,798,426...91,865,475
Ensembl chr10:91,798,426...91,865,475
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IMP (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link
regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase NOT|involved_in IMP (PMID:26586427) BHF-UCL PMID:26586427 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G HMBOX1 homeobox containing 1 involved_in IDA (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,890,394...29,064,945
Ensembl chr 8:28,890,395...29,064,764
JBrowse link
G NABP2 nucleic acid binding protein 2 NOT|involved_in IMP (PMID:25589350) BHF-UCL PMID:25589350 NCBI chr12:56,222,012...56,229,858
Ensembl chr12:56,222,015...56,229,854
JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 involved_in IDA (PMID:15169895) BHF-UCL PMID:15169895 NCBI chr13:24,420,930...24,512,993
Ensembl chr13:24,420,931...24,512,778
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in TAS (PMID:15381700) UniProt PMID:15381700 NCBI chr 8:10,764,961...10,839,875
Ensembl chr 8:10,725,399...10,839,847
Ensembl chr 8:10,725,399...10,839,847
JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor involved_in IC (PMID:22011238) BHF-UCL PMID:22011238 NCBI chr17:2,059,839...2,303,836
Ensembl chr17:2,059,839...2,303,785
JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in IGI (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G POT1 protection of telomeres 1 involved_in IBA
IGI
(PMID:21873635)
(PMID:26586433)
GO_Central
BHF-UCL
PMID:21873635 PMID:26586433 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G SMG5 SMG5 nonsense mediated mRNA decay factor involved_in TAS (PMID:16507993) BHF-UCL PMID:16507993 NCBI chr 1:156,249,224...156,291,516
Ensembl chr 1:156,249,224...156,282,825
JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor involved_in TAS
IC
(PMID:16507993)
(PMID:22011238)
BHF-UCL PMID:16507993 PMID:22011238 NCBI chr17:2,059,839...2,303,836
Ensembl chr17:2,059,839...2,303,785
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IMP
IBA
IDA
(PMID:19864690)
(PMID:21873635)
(PMID:23685356)
BHF-UCL
GO_Central
PMID:19864690 PMID:21873635 PMID:23685356 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TNKS tankyrase involved_in IC (PMID:9822378) BHF-UCL PMID:9822378 NCBI chr 8:9,555,230...9,782,346
Ensembl chr 8:9,555,912...9,782,346
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18534
    regulation of biological process 12363
      regulation of metabolic process 7180
        regulation of macromolecule metabolic process 6639
          regulation of DNA metabolic process 405
            regulation of DNA biosynthetic process 128
              negative regulation of DNA biosynthetic process + 44
              positive regulation of DNA biosynthetic process + 78
              regulation of DNA amplification + 0
              regulation of DNA-directed DNA polymerase activity + 10
              regulation of error-prone translesion synthesis + 0
              regulation of reverse transcription + 0
              regulation of telomerase activity + 53
              regulation of telomere maintenance via telomerase + 55
Path 2
Term Annotations click to browse term
  biological_process 18534
    metabolic process 11862
      cellular metabolic process 10839
        cellular aromatic compound metabolic process 6052
          nucleobase-containing compound metabolic process 5812
            nucleic acid metabolic process 5309
              DNA metabolic process 963
                regulation of DNA metabolic process 405
                  regulation of DNA biosynthetic process 128
                    negative regulation of DNA biosynthetic process + 44
                    positive regulation of DNA biosynthetic process + 78
                    regulation of DNA amplification + 0
                    regulation of DNA-directed DNA polymerase activity + 10
                    regulation of error-prone translesion synthesis + 0
                    regulation of reverse transcription + 0
                    regulation of telomerase activity + 53
                    regulation of telomere maintenance via telomerase + 55
paths to the root