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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA biosynthetic process
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Accession:GO:2000278 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
Synonyms:exact_synonym: regulation of DNA anabolism;   regulation of DNA biosynthesis;   regulation of DNA formation;   regulation of DNA synthesis


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regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A ISO (MGI:MGI:3617096|PMID:11981756) MGI PMID:11981756 MGI:MGI:3617096 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G PDGFA platelet derived growth factor subunit A NOT ISO (PMID:11788434), (PMID:19019919) UniProtKB PMID:11788434, PMID:19019919 NCBI chr 7:648,722...672,023 JBrowse link
G SH2B1 SH2B adaptor protein 1 ISO (MGI:MGI:5009204|PMID:10644978) UniProtKB PMID:10644978 MGI:MGI:5009204 Ensembl chr16:29,249,597...29,263,334 JBrowse link
G TFDP1 transcription factor Dp-1 ISO (MGI:MGI:3525422|PMID:15448153) MGI PMID:15448153 MGI:MGI:3525422 NCBI chr13:94,730,343...94,789,328
Ensembl chr13:113,789,280...113,840,825
JBrowse link
G TOM1L1 target of myb1 like 1 membrane trafficking protein NOT ISO (PMID:16479011) UniProtKB PMID:16479011 NCBI chr17:48,990,121...49,050,703
Ensembl chr17:53,855,447...53,916,592
JBrowse link
negative regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr12:36,839,869...36,856,351
Ensembl chr12:37,615,888...37,631,691
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO (PMID:12070119) UniProtKB PMID:12070119 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AHR aryl hydrocarbon receptor ISO RGD PMID:12193573 RGD:625678 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G ANKRD1 ankyrin repeat domain 1 ISO (PMID:11139470) BHF-UCL PMID:11139470 NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CHEK1 checkpoint kinase 1 ISO RGD PMID:12429946 RGD:2316115 NCBI chr11:120,446,352...120,478,207 JBrowse link
G DACH1 dachshund family transcription factor 1 ISO (PMID:16980615) CACAO PMID:16980615 NCBI chr13:52,666,569...53,098,257 JBrowse link
G DNAJC2 DnaJ heat shock protein family (Hsp40) member C2 ISO (MGI:MGI:76992|PMID:7559602) MGI PMID:7559602 MGI:MGI:76992 NCBI chr 7:95,303,823...95,336,085
Ensembl chr 7:108,048,307...108,080,127
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:10446064 RGD:7771571 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G GDF2 growth differentiation factor 2 ISO (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr10:46,520,808...46,526,414 JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:14702389 RGD:8662403 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:23271285 RGD:9831181 NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840
JBrowse link
G NIBAN2 niban apoptosis regulator 2 ISO (PMID:14602737), (PMID:17569660), (PMID:20032057) UniProtKB PMID:14602737, PMID:17569660, PMID:20032057 NCBI chr 9:98,625,411...98,689,077
Ensembl chr 9:127,299,475...127,371,459
JBrowse link
G NPPC natriuretic peptide C ISO RGD PMID:12746286 RGD:1580115 NCBI chr2B:119,148,774...119,153,381
Ensembl chr2B:237,936,939...237,941,244
JBrowse link
G RGN regucalcin ISO RGD PMID:11500948 RGD:9590199 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:11502571 RGD:70312 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CERS1 ceramide synthase 1 ISO (PMID:17548428) UniProtKB PMID:17548428 NCBI chr19:18,308,265...18,334,892 JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit NOT ISO (PMID:18812185) BHF-UCL PMID:18812185 NCBI chr16:12,848,334...12,880,480
Ensembl chr16:14,272,417...14,304,496
JBrowse link
G MCRS1 microspherule protein 1 ISO (PMID:15044100) BHF-UCL PMID:15044100 NCBI chr12:39,183,112...39,192,925
Ensembl chr12:40,073,860...40,083,655
JBrowse link
G MEN1 menin 1 ISO (PMID:12837246) UniProtKB PMID:12837246 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase ISO (PMID:16522649) HGNC PMID:16522649 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 ISO (PMID:11701125), (PMID:21119197) BHF-UCL PMID:11701125, PMID:21119197 NCBI chr 8:8,366,819...8,443,359 JBrowse link
G PML PML nuclear body scaffold ISO (PMID:19567472) UniProtKB PMID:19567472 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POT1 protection of telomeres 1 ISO (PMID:15632080) BHF-UCL PMID:15632080 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO RGD PMID:16556873 RGD:1580657 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TERF1 telomeric repeat binding factor 1 ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr 8:69,545,115...69,583,997 JBrowse link
G TP53 tumor protein p53 ISO (PMID:10597287) BHF-UCL PMID:10597287 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
negative regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 ISO (PMID:24528514) BHF-UCL PMID:24528514 NCBI chr 3:51,883,695...51,890,266
Ensembl chr 3:53,112,494...53,119,053
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor ISO (PMID:15380063)
(PMID:15181449)
BHF-UCL PMID:15181449, PMID:15380063 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G CTC1 CST telomere replication complex component 1 ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:43,410,385...43,433,784
Ensembl chr17:48,142,864...48,165,537
JBrowse link
G DCP2 decapping mRNA 2 ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 5:108,333,091...108,377,119
Ensembl chr 5:114,144,999...114,172,480
JBrowse link
G EXOSC10 exosome component 10 ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 1:9,829,922...9,865,092
Ensembl chr 1:11,050,727...11,087,241
JBrowse link
G GNL3L G protein nucleolar 3 like ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:46,733,431...46,825,139
Ensembl chr  X:54,966,121...55,002,925
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr14:2,022,280...2,083,215 JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031
JBrowse link
G NAT10 N-acetyltransferase 10 ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr11:34,082,304...34,127,793
Ensembl chr11:33,960,739...34,002,069
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase ISO (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 ISO (PMID:11701125)
(PMID:21119197)
BHF-UCL PMID:11701125, PMID:21119197 NCBI chr 8:8,366,819...8,443,359 JBrowse link
G PML PML nuclear body scaffold ISO (PMID:19567472) UniProtKB PMID:19567472 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G POT1 protection of telomeres 1 ISO (PMID:15181449) BHF-UCL PMID:15181449 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G STN1 STN1 subunit of CST complex ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr10:100,456,589...100,518,010
Ensembl chr10:103,942,422...103,977,847
JBrowse link
G TEN1 TEN1 subunit of CST complex ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:69,928,204...69,947,138 JBrowse link
G TENT4B terminal nucleotidyltransferase 4B ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr16:30,415,668...30,494,758
Ensembl chr16:49,299,498...49,373,665
JBrowse link
G TERF1 telomeric repeat binding factor 1 ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr 8:69,545,115...69,583,997 JBrowse link
G TERF2 telomeric repeat binding factor 2 ISO (PMID:17055345)
(PMID:11971978)
BHF-UCL PMID:11971978, PMID:17055345 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 ISO (PMID:15133513)
(PMID:10581025)
BHF-UCL PMID:10581025, PMID:15133513 NCBI chr14:5,015,862...5,019,228
Ensembl chr14:23,139,445...23,142,825
JBrowse link
positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO RGD PMID:19254952 RGD:5509898 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517
JBrowse link
G C3AR1 complement C3a receptor 1 ISO RGD PMID:23713944 RGD:7411623 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16005543 RGD:5131269 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:20439821 RGD:7829726 NCBI chr2A:38,087,863...38,096,529 JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:22446327 RGD:10401140 NCBI chr 6:31,191,333...31,203,246
Ensembl chr 6:32,081,210...32,092,569
JBrowse link
G FGF2 fibroblast growth factor 2 ISO (PMID:16774925) UniProtKB PMID:16774925 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 ISO (PMID:21653700) UniProtKB PMID:21653700 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605
JBrowse link
G GFER growth factor, augmenter of liver regeneration ISO RGD PMID:16937468 RGD:9685728 NCBI chr16:716,640...720,196
Ensembl chr16:2,073,064...2,076,592
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:12721208 RGD:10045365 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G HGF hepatocyte growth factor ISO (PMID:2531289) UniProtKB PMID:2531289 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (PMID:9924025) UniProtKB PMID:9924025 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NOX4 NADPH oxidase 4 ISO (MGI:MGI:5009390|PMID:17942966) UniProtKB PMID:17942966 MGI:MGI:5009390 NCBI chr11:84,330,362...84,496,755 JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 ISO RGD PMID:12890786 RGD:7775030 NCBI chr  X:100,060,647...100,345,491
Ensembl chr  X:110,672,664...110,797,992
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919) UniProtKB PMID:10644978, PMID:10734101, PMID:11788434, PMID:12070119, PMID:16530387, PMID:17942966, PMID:19019919 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO (MGI:MGI:5284758|PMID:19019919) UniProtKB PMID:19019919 MGI:MGI:5284758 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PRKD2 protein kinase D2 ISO (MGI:MGI:5306299|PMID:17226786) UniProtKB PMID:17226786 MGI:MGI:5306299 NCBI chr19:43,666,591...43,710,858
Ensembl chr19:52,195,303...52,237,731
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:21451101 RGD:10041071 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G RGCC regulator of cell cycle ISO PMID:9756947 BHF-UCL PMID:9756947 RGD:633887 NCBI chr13:22,639,289...22,652,594
Ensembl chr13:41,228,643...41,241,909
JBrowse link
G SMOC2 SPARC related modular calcium binding 2 ISO (PMID:16774925) UniProtKB PMID:16774925 NCBI chr 6:166,430,178...166,664,577
Ensembl chr 6:171,366,929...171,589,084
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9395232 RGD:14696805 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G VEGFA vascular endothelial growth factor A ISO (PMID:16774925) UniProtKB PMID:16774925 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHTF18 chromosome transmission fidelity factor 18 ISO (PMID:12930902) UniProtKB PMID:12930902 Ensembl chr16:803,340...813,170 JBrowse link
G CHTF8 chromosome transmission fidelity factor 8 ISO (PMID:12930902) UniProtKB PMID:12930902 NCBI chr16:49,489,176...49,503,736 JBrowse link
G DSCC1 DNA replication and sister chromatid cohesion 1 ISO (PMID:12930902) UniProtKB PMID:12930902 NCBI chr 8:116,524,249...116,546,178
Ensembl chr 8:119,272,490...119,294,342
JBrowse link
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656
JBrowse link
G PCNA proliferating cell nuclear antigen ISO (PMID:11595739) UniProt PMID:11595739 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440
JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) FlyBase PMID:10608893, PMID:19837034, PMID:19858216, PMID:26123486 NCBI chr17:58,574,442...58,593,915
Ensembl chr17:63,667,246...63,686,503
JBrowse link
G RFC2 replication factor C subunit 2 ISO (PMID:12930902) UniProtKB PMID:12930902 Ensembl chr 7:81,378,937...81,401,937 JBrowse link
G RFC3 replication factor C subunit 3 ISO (PMID:12930902) UniProtKB PMID:12930902 NCBI chr13:15,073,464...15,220,646
Ensembl chr13:33,503,439...33,523,403
JBrowse link
G RFC4 replication factor C subunit 4 ISO (PMID:12930902) UniProtKB PMID:12930902 NCBI chr 3:183,824,865...183,841,895
Ensembl chr 3:192,290,639...192,307,839
JBrowse link
G RFC5 replication factor C subunit 5 ISO (PMID:12930902) UniProtKB PMID:12930902 NCBI chr12:115,595,398...115,611,442
Ensembl chr12:118,973,560...118,990,308
JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G AURKB aurora kinase B ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CTNNB1 catenin beta 1 ISO (MGI:MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 ISO (PMID:25467444)
(MGI:MGI:3047190|PMID:15240872)
BHF-UCL
MGI
PMID:15240872, PMID:25467444 MGI:MGI:3047190 NCBI chr  X:144,243,493...144,257,419
Ensembl chr  X:154,084,412...154,098,475
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO (PMID:16545136) BHF-UCL PMID:16545136 NCBI chr15:11,213,870...11,230,619 JBrowse link
G GRHL2 grainyhead like transcription factor 2 ISO (PMID:19015635), (PMID:20938050) UniProtKB PMID:19015635, PMID:20938050 NCBI chr 8:98,129,147...98,308,120
Ensembl chr 8:100,308,575...100,471,830
JBrowse link
G HMBOX1 homeobox containing 1 ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO (PMID:10197982) BHF-UCL PMID:10197982 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872
JBrowse link
G KLF4 Kruppel like factor 4 ISO (PMID:20629177) BHF-UCL PMID:20629177 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO (MGI:MGI:5810267|PMID:9637678) BHF-UCL PMID:9637678 MGI:MGI:5810267 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein ISO (PMID:27510903) BHF-UCL PMID:27510903 NCBI chr 4:155,383,245...155,425,479
Ensembl chr 4:167,157,770...167,214,065
JBrowse link
G NEK2 NIMA related kinase 2 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G NVL nuclear VCP like ISO (PMID:22226966) UniProtKB PMID:22226966 NCBI chr 1:199,695,388...199,798,080
Ensembl chr 1:204,704,371...204,806,959
JBrowse link
G PARM1 prostate androgen-regulated mucin-like protein 1 ISO PMID:12772192 UniProt PMID:12772192 RGD:8553456 NCBI chr 4:49,153,654...49,270,384
Ensembl chr 4:54,987,767...55,104,461
JBrowse link
G PARN poly(A)-specific ribonuclease ISO (PMID:26482878) BHF-UCL PMID:26482878 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G POT1 protection of telomeres 1 ISO (PMID:15181449)
(PMID:16043710), (PMID:17237768)
BHF-UCL PMID:15181449, PMID:16043710, PMID:17237768 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PRKCQ protein kinase C theta ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G PTGES3 prostaglandin E synthase 3 ISO (MGI:MGI:5819359|PMID:10197982)
(PMID:19740745)
(PMID:10197982), (PMID:19740745)
BHF-UCL PMID:10197982, PMID:19740745 MGI:MGI:5819359 NCBI chr12:32,221,908...32,247,228
Ensembl chr12:32,476,835...32,503,181
JBrowse link
G TCP1 t-complex 1 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985
JBrowse link
G TNKS tankyrase ISO (PMID:12782650) BHF-UCL PMID:12782650 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G WRAP53 WD repeat containing antisense to TP53 ISO (MGI:MGI:6189679|PMID:29804836)
(PMID:23685356), (PMID:25467444)
(PMID:19179534), (PMID:23685356), (PMID:29804836)
UniProtKB
BHF-UCL
PMID:19179534, PMID:23685356, PMID:25467444, PMID:29804836 MGI:MGI:6189679 NCBI chr17:7,715,897...7,735,873
Ensembl chr17:7,707,221...7,723,394
JBrowse link
positive regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 7:26,835,881...26,846,578
Ensembl chr 7:26,439,443...26,449,985
JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D ISO (MGI:MGI:5438900|PMID:22633954) BHF-UCL PMID:22633954 MGI:MGI:5438900 NCBI chr 4:41,825,518...41,846,166
Ensembl chr 4:47,676,599...47,696,894
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:48,001,408...48,004,620
Ensembl chr16:67,390,703...67,393,685
JBrowse link
G ATM ATM serine/threonine kinase ISO (MGI:MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:MGI:5705431 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G ATR ATR serine/threonine kinase ISO (MGI:MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:MGI:5705431 NCBI chr 3:139,482,606...139,612,274
Ensembl chr 3:147,075,185...147,196,261
JBrowse link
G AURKB aurora kinase B ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 1:131,652,058...131,679,802
Ensembl chr 1:135,481,427...135,508,983
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 5:10,565,911...10,580,808
Ensembl chr 5:10,424,157...10,440,613
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:56,664,757...56,677,000
Ensembl chr 7:57,087,072...57,098,613
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr2A:73,287,026...73,305,792
Ensembl chr2A:74,775,781...74,794,515
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr21:15,489,698...15,507,292
Ensembl chr21:28,878,113...28,895,912
JBrowse link
G CTNNB1 catenin beta 1 ISO (MGI:MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:MGI:5428344 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 ISO (MGI:MGI:3047190|PMID:15240872) MGI PMID:15240872 MGI:MGI:3047190 NCBI chr  X:144,243,493...144,257,419
Ensembl chr  X:154,084,412...154,098,475
JBrowse link
G FBXO4 F-box protein 4 ISO (PMID:16275645) BHF-UCL PMID:16275645 NCBI chr 5:68,336,673...68,474,481
Ensembl chr 5:73,500,850...73,517,051
JBrowse link
G HMBOX1 homeobox containing 1 ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:34,456,900...34,463,317
Ensembl chr12:35,184,943...35,188,443
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:158,937,424...159,062,550
Ensembl chr 6:163,948,122...164,073,264
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:140,468,365...140,474,604
Ensembl chr 8:143,481,567...143,492,859
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO (PMID:21531765) BHF-UCL PMID:21531765 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:109,416,610...109,471,729
Ensembl chr12:112,812,769...112,863,595
JBrowse link
G NEK2 NIMA related kinase 2 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:187,225,947...187,243,605
Ensembl chr 1:192,092,885...192,105,737
JBrowse link
G NEK7 NIMA related kinase 7 ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:173,752,892...173,918,258
Ensembl chr 1:178,138,925...178,228,197
JBrowse link
G PARN poly(A)-specific ribonuclease ISO (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878, PMID:26950371 NCBI chr16:13,363,879...13,556,054
Ensembl chr16:14,787,881...14,977,786
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:120,373,497...120,517,119
Ensembl chr 6:124,612,910...124,640,260
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:46,874,216...46,880,954
Ensembl chr19:55,790,048...55,796,762
JBrowse link
G POT1 protection of telomeres 1 ISO (PMID:17237768)
(PMID:12768206), (PMID:12781132)
BHF-UCL PMID:12768206, PMID:12781132, PMID:17237768 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G PRKCQ protein kinase C theta ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900
JBrowse link
G TCP1 t-complex 1 ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985
JBrowse link
G TNKS tankyrase ISO (PMID:11739745)
(PMID:12782650), (PMID:18221737)
BHF-UCL PMID:11739745, PMID:12782650, PMID:18221737 NCBI chr 8:9,435,412...9,654,810 JBrowse link
G XRCC5 X-ray repair cross complementing 5 ISO (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr2B:103,371,459...103,468,419
Ensembl chr2B:221,972,742...222,071,235
JBrowse link
regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase NOT ISO (PMID:26586427) BHF-UCL PMID:26586427 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G HMBOX1 homeobox containing 1 ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,173,256...28,350,591
Ensembl chr 8:25,446,264...25,547,208
JBrowse link
G NABP2 nucleic acid binding protein 2 NOT ISO (PMID:25589350) BHF-UCL PMID:25589350 NCBI chr12:32,685,521...32,693,318
Ensembl chr12:32,937,017...32,944,754
JBrowse link
G PARP4 poly(ADP-ribose) polymerase family member 4 ISO (PMID:15169895) BHF-UCL PMID:15169895 NCBI chr13:5,734,322...5,827,323
Ensembl chr13:24,029,405...24,113,075
JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G POT1 protection of telomeres 1 ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr 7:116,807,913...116,926,998
Ensembl chr 7:129,487,571...129,605,558
JBrowse link
G TERF2 telomeric repeat binding factor 2 ISO (PMID:23685356)
(PMID:19864690)
BHF-UCL PMID:19864690, PMID:23685356 NCBI chr16:49,729,906...49,763,002
Ensembl chr16:69,116,539...69,148,423
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    regulation of biological process 8652
      regulation of metabolic process 5285
        regulation of macromolecule metabolic process 4849
          regulation of DNA metabolic process 362
            regulation of DNA biosynthetic process 122
              negative regulation of DNA biosynthetic process + 43
              positive regulation of DNA biosynthetic process + 77
              regulation of DNA amplification + 0
              regulation of DNA-directed DNA polymerase activity + 10
              regulation of error-prone translesion synthesis + 0
              regulation of reverse transcription + 0
              regulation of telomerase activity + 50
              regulation of telomere maintenance via telomerase + 49
Path 2
Term Annotations click to browse term
  biological_process 12529
    metabolic process 7962
      cellular metabolic process 7310
        cellular aromatic compound metabolic process 3867
          nucleobase-containing compound metabolic process 3691
            nucleic acid metabolic process 3388
              DNA metabolic process 671
                regulation of DNA metabolic process 362
                  regulation of DNA biosynthetic process 122
                    negative regulation of DNA biosynthetic process + 43
                    positive regulation of DNA biosynthetic process + 77
                    regulation of DNA amplification + 0
                    regulation of DNA-directed DNA polymerase activity + 10
                    regulation of error-prone translesion synthesis + 0
                    regulation of reverse transcription + 0
                    regulation of telomerase activity + 50
                    regulation of telomere maintenance via telomerase + 49
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.