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ONTOLOGY REPORT - ANNOTATIONS
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Term:
negative regulation of signaling receptor activity
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Accession:
GO:2000272
browse the term
Definition:
Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.
Synonyms:
exact_synonym:
negative regulation of signalling receptor activity
broad_synonym:
negative regulation of receptor activity
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Rat (4)
Mouse (4)
Human (4)
Chinchilla (4)
Bonobo (4)
Dog (4)
Squirrel (4)
Pig (4)
Green Monkey (4)
Naked Mole-rat (4)
All
Genes (4)
negative regulation of signaling receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ppargc1a
PPARG coactivator 1 alpha
ISO
extrasynaptic NMDAR
RGD
PMID:22593067
RGD:6484258
NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
G
Pten
phosphatase and tensin homolog
ISO
GABA A receptors
RGD
PMID:24044036
RGD:12802358
NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829
negative regulation of AMPA receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Grip1
glutamate receptor interacting protein 1
ISO
RGD
PMID:12597860
RGD:152995391
NCBI chrNW_004955458:12,970,858...13,179,369
Ensembl chrNW_004955458:12,967,089...13,214,838
negative regulation of NMDA glutamate receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Park7
Parkinsonism associated deglycase
ISO
RGD
PMID:20698836
RGD:13463453
NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
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Path 1
Term
Annotations
biological_process
12321
biological regulation
8863
regulation of molecular function
300
regulation of signaling receptor activity
17
negative regulation of signaling receptor activity
4
cross-receptor inhibition within G protein-coupled receptor heterodimer
0
negative regulation of AMPA receptor activity
1
negative regulation of GABA-A receptor activity
0
negative regulation of NMDA glutamate receptor activity
1
negative regulation of acetylcholine-gated cation channel activity
0
negative regulation of advanced glycation end-product receptor activity
0
negative regulation of brain-derived neurotrophic factor-activated receptor activity
0
negative regulation of corticotropin-releasing hormone receptor activity
0
negative regulation of epidermal growth factor-activated receptor activity
0
negative regulation of nerve growth factor receptor activity
0
negative regulation of osmolarity-sensing cation channel activity
0
negative regulation of proteinase activated receptor activity
0
Path 2
Term
Annotations
biological_process
12321
biological regulation
8863
regulation of biological process
8603
signaling
4437
regulation of signaling
3102
regulation of signal transduction
2620
regulation of signaling receptor activity
17
negative regulation of signaling receptor activity
4
cross-receptor inhibition within G protein-coupled receptor heterodimer
0
negative regulation of AMPA receptor activity
1
negative regulation of GABA-A receptor activity
0
negative regulation of NMDA glutamate receptor activity
1
negative regulation of acetylcholine-gated cation channel activity
0
negative regulation of advanced glycation end-product receptor activity
0
negative regulation of brain-derived neurotrophic factor-activated receptor activity
0
negative regulation of corticotropin-releasing hormone receptor activity
0
negative regulation of epidermal growth factor-activated receptor activity
0
negative regulation of nerve growth factor receptor activity
0
negative regulation of osmolarity-sensing cation channel activity
0
negative regulation of proteinase activated receptor activity
0