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ONTOLOGY REPORT - ANNOTATIONS
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Term:
negative regulation of signaling receptor activity
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Accession:
GO:2000272
browse the term
Definition:
Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.
Synonyms:
exact_synonym:
negative regulation of signalling receptor activity
broad_synonym:
negative regulation of receptor activity
show annotations for term's descendants Sort by:
symbol
object name
position
reference
evidence
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Rat (4)
Mouse (4)
Human (4)
Chinchilla (4)
Bonobo (4)
Dog (4)
Squirrel (4)
Pig (4)
Green Monkey (4)
Naked Mole-rat (4)
All
Genes (4)
negative regulation of signaling receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Ppargc1a
PPARG coactivator 1 alpha
IMP
extrasynaptic NMDAR
RGD
PMID:22593067
RGD:6484258
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Pten
phosphatase and tensin homolog
IMP
GABA A receptors
RGD
PMID:24044036
RGD:12802358
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
negative regulation of AMPA receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Grip1
glutamate receptor interacting protein 1
IMP
RGD
PMID:12597860
RGD:152995391
NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
negative regulation of NMDA glutamate receptor activity
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Park7
Parkinsonism associated deglycase
IMP
RGD
PMID:20698836
RGD:13463453
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
19553
biological regulation
13187
regulation of molecular function
323
regulation of signaling receptor activity
17
negative regulation of signaling receptor activity
4
cross-receptor inhibition within G protein-coupled receptor heterodimer
0
negative regulation of AMPA receptor activity
1
negative regulation of GABA-A receptor activity
0
negative regulation of NMDA glutamate receptor activity
1
negative regulation of acetylcholine-gated cation channel activity
0
negative regulation of advanced glycation end-product receptor activity
0
negative regulation of brain-derived neurotrophic factor-activated receptor activity
0
negative regulation of corticotropin-releasing hormone receptor activity
0
negative regulation of epidermal growth factor-activated receptor activity
0
negative regulation of nerve growth factor receptor activity
0
negative regulation of osmolarity-sensing cation channel activity
0
negative regulation of proteinase activated receptor activity
0
Path 2
Term
Annotations
biological_process
19553
biological regulation
13187
regulation of biological process
12813
signaling
7552
regulation of signaling
3686
regulation of signal transduction
3125
regulation of signaling receptor activity
17
negative regulation of signaling receptor activity
4
cross-receptor inhibition within G protein-coupled receptor heterodimer
0
negative regulation of AMPA receptor activity
1
negative regulation of GABA-A receptor activity
0
negative regulation of NMDA glutamate receptor activity
1
negative regulation of acetylcholine-gated cation channel activity
0
negative regulation of advanced glycation end-product receptor activity
0
negative regulation of brain-derived neurotrophic factor-activated receptor activity
0
negative regulation of corticotropin-releasing hormone receptor activity
0
negative regulation of epidermal growth factor-activated receptor activity
0
negative regulation of nerve growth factor receptor activity
0
negative regulation of osmolarity-sensing cation channel activity
0
negative regulation of proteinase activated receptor activity
0