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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of DNA-templated transcription initiation
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Accession:GO:2000144 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
Synonyms:exact_synonym: positive regulation of DNA-dependent transcription, initiation;   positive regulation of initiation of DNA-dependent transcription
 related_synonym: transactivation;   transcriptional transactivation


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positive regulation of DNA-templated transcription initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO (PMID:17938203) RGD PMID:17938203 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha involved_in ISO (PMID:28186500) RGD PMID:28186500 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit involved_in ISO (PMID:23027619) RGD PMID:23027619 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:23027619) RGD PMID:23027619 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mitf melanocyte inducing transcription factor involved_in ISO
IEA		 (PMID:12204775), (PMID:8995290)
GO_REF:0000107		 RGD
Ensembl		 PMID:8995290 PMID:12204775 GO_REF:0000107 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Setx senataxin involved_in ISO (PMID:21700224) RGD PMID:21700224 NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17332325) RGD PMID:17332325 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor acts_upstream_of_or_within ISO (PMID:8215422) RGD PMID:8215422 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 involved_in IDA PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr 7:54,681,114...54,719,002
Ensembl chr 7:54,680,900...54,718,993 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158690 (PMID:21245044) RGD PMID:21245044 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (PMID:24289924)
GO_REF:0000107		 RGD
Ensembl		 PMID:24289924 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:19056892) RGD PMID:19056892 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
positive regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21993297)		 UniProt
RGD		 PMID:21993297 GO_REF:0000024 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:22323595) RGD PMID:22323595 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102|MGI:99135 (PMID:22323595) RGD PMID:22323595 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 involved_in ISO (PMID:11030333) RGD PMID:11030333 NCBI chr 6:110,488,891...110,521,502
Ensembl chr 6:110,488,931...110,521,511 		JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 involved_in ISO (PMID:11030333) RGD PMID:11030333 NCBI chr 8:70,662,447...70,675,576
Ensembl chr 8:70,662,428...70,675,569 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO UniProtKB:P35680 (PMID:15355349) RGD PMID:15355349 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in ISO
IEA		 (PMID:15355349)
GO_REF:0000107		 RGD
Ensembl		 PMID:15355349 GO_REF:0000107 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Kat8 lysine acetyltransferase 8 involved_in ISO
IEA
ISS		 (PMID:33657400)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:33657400 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:182,524,355...182,536,638
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G LOC103693281 activated RNA polymerase II transcriptional coactivator p15 pseudogene involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:12,858,465...12,858,878
Ensembl chr15:12,858,465...12,858,845
Ensembl chr15:12,858,465...12,858,845 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12218053), (PMID:16314496)		 UniProt
RGD		 PMID:12218053 PMID:16314496 GO_REF:0000024 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Med12 mediator complex subunit 12 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr  X:66,404,807...66,427,775
Ensembl chr  X:66,404,760...66,428,387 		JBrowse link
G Med13 mediator complex subunit 13 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr10:71,086,978...71,176,535
Ensembl chr10:71,090,516...71,177,242 		JBrowse link
G Med14 mediator complex subunit 14 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr  X:10,036,749...10,127,910
Ensembl chr  X:10,036,805...10,126,240 		JBrowse link
G Med16 mediator complex subunit 16 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 7:9,798,641...9,811,172
Ensembl chr 7:9,798,668...9,811,172 		JBrowse link
G Med17 mediator complex subunit 17 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 8:12,101,594...12,120,592
Ensembl chr 8:12,101,594...12,120,592 		JBrowse link
G Med24 mediator complex subunit 24 involved_in ISO
IBA
IEA		 (PMID:12218053)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:12218053 GO_REF:0000033 GO_REF:0000107 NCBI chr10:83,664,609...83,702,315
Ensembl chr10:83,664,609...83,690,123 		JBrowse link
G Med30 mediator complex subunit 30 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 7:84,004,735...84,026,474
Ensembl chr 7:84,004,722...84,026,595 		JBrowse link
G Med4 mediator complex subunit 4 involved_in ISO
IEA		 (PMID:12218053)
GO_REF:0000107		 RGD
Ensembl		 PMID:12218053 GO_REF:0000107 NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:6377809 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16322095)		 Ensembl
RGD		 PMID:16322095 GO_REF:0000107 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16322095) RGD PMID:16322095 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:83559|PMID:8887666)		 Ensembl
RGD		 PMID:8887666 GO_REF:0000107 MGI:83559 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO
IBA		 (PMID:17925232)
GO_REF:0000033
(MGI:4354659|PMID:19583951), (MGI:4821506|PMID:20671152)		 RGD
GO_Central		 PMID:17925232 PMID:19583951 PMID:20671152 GO_REF:0000033 MGI:4354659 MGI:4821506 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:6377809 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Srf serum response factor involved_in ISO (PMID:8887666) RGD PMID:8887666 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Sub1 SUB1 regulator of transcription involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376 		JBrowse link
G Taf11 TATA-box binding protein associated factor 11 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr20:5,955,774...5,963,593
Ensembl chr20:5,955,777...5,961,905 		JBrowse link
G Taf12 TATA-box binding protein associated factor 12 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 5:144,472,816...144,490,299
Ensembl chr 5:144,472,841...144,488,849 		JBrowse link
G Taf13 TATA-box binding protein associated factor 13 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878 		JBrowse link
G Taf2 TATA-box binding protein associated factor 2 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 7:86,422,613...86,479,616
Ensembl chr 7:86,422,613...86,479,616 		JBrowse link
G Taf3 TATA-box binding protein associated factor 3 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr17:68,455,389...68,608,367
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Taf4 TATA-box binding protein associated factor 4 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 3:167,017,992...167,083,413
Ensembl chr 3:167,017,993...167,083,356 		JBrowse link
G Taf4b TATA-box binding protein associated factor 4b involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr18:5,952,737...6,086,408
Ensembl chr18:5,952,769...6,068,307 		JBrowse link
G Taf5 TATA-box binding protein associated factor 5 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 1:245,958,428...245,973,914
Ensembl chr 1:245,958,428...245,973,914 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO
IEA		 (PMID:11583621), (PMID:18628956)
GO_REF:0000107
(PMID:17884155)		 RGD
Ensembl		 PMID:11583621 PMID:17884155 PMID:18628956 GO_REF:0000107 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Taf8 TATA-box binding protein associated factor 8 involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 9:13,491,892...13,511,713
Ensembl chr 9:13,491,937...13,511,717 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO
IEA		 (PMID:17884155)
GO_REF:0000107		 RGD
Ensembl		 PMID:17884155 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tbp TATA box binding protein involved_in ISO (PMID:17884155) RGD PMID:17884155 NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:1100494 (PMID:22323595) RGD PMID:22323595 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (MGI:6106288|PMID:29138493) RGD PMID:29138493 MGI:6106288 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      macromolecule metabolic process 10146
        macromolecule biosynthetic process 7442
          gene expression 6970
            DNA-templated transcription 3497
              DNA-templated transcription initiation 183
                positive regulation of DNA-templated transcription initiation 58
                  positive regulation of transcription initiation by RNA polymerase II + 51
Path 2
Term Annotations click to browse term
  biological_process 20115
    biological regulation 13553
      regulation of biological process 13127
        regulation of metabolic process 6817
          regulation of biosynthetic process 5480
            regulation of cellular biosynthetic process 5384
              regulation of macromolecule biosynthetic process 5283
                regulation of RNA biosynthetic process 3342
                  regulation of DNA-templated transcription 3332
                    regulation of DNA-templated transcription initiation 69
                      positive regulation of DNA-templated transcription initiation 58
                        positive regulation of transcription initiation by RNA polymerase II + 51
paths to the root