Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of cysteine-type endopeptidase activity
go back to main search page
Accession:GO:2000117 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.
Synonyms:exact_synonym: negative regulation of thiol endopeptidase activity
 related_synonym: negative regulation of lysosomal cysteine-type endopeptidase


show annotations for term's descendants           Sort by:
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23690069 RGD:13792722 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
G HTT huntingtin ISO RGD PMID:17124493 RGD:6902918 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730 		JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517 		JBrowse link
G EP300 E1A binding protein p300 ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chr19:31,301,469...31,355,362
Ensembl chr19:40,024,584...40,080,598 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:21874357 RGD:150540304 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B ISO reduced cleavage of Casp8 and Casp9 in brain following hypoxic/ischemic injury RGD PMID:16397188 RGD:1626654 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G IL6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G PTMA prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chr2B:118,959,382...118,964,364 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      primary metabolic process 8922
        protein metabolic process 3923
          proteolysis 1360
            negative regulation of proteolysis 150
              negative regulation of peptidase activity 19
                negative regulation of endopeptidase activity 19
                  negative regulation of cysteine-type endopeptidase activity 14
                    inhibition of cysteine-type endopeptidase activity + 0
                    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process + 12
Path 2
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        macromolecule metabolic process 8341
          protein metabolic process 3923
            proteolysis 1360
              regulation of proteolysis 411
                negative regulation of proteolysis 150
                  negative regulation of peptidase activity 19
                    negative regulation of endopeptidase activity 19
                      negative regulation of cysteine-type endopeptidase activity 14
                        inhibition of cysteine-type endopeptidase activity + 0
                        negative regulation of cysteine-type endopeptidase activity involved in apoptotic process + 12
paths to the root