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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of leukocyte apoptotic process
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Accession:GO:2000107 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.
Synonyms:narrow_synonym: negative regulation of leukocyte apoptosis


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negative regulation of leukocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095 		JBrowse link
G MERTK MER proto-oncogene, tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,977,226...90,109,970
Ensembl chr2A:113,056,852...113,162,052 		JBrowse link
negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:2387354 NCBI chr 8:130,111,085...130,227,195
Ensembl chr 8:133,084,835...133,119,791 		JBrowse link
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain involved_in ISO (MGI:5291865|PMID:21876153) UniProt PMID:21876153 MGI:5291865 NCBI chr11:65,300,889...65,305,020 JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18971390) Ensembl
MGI		 PMID:18971390 GO_REF:0000107 NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549 		JBrowse link
G TNFRSF4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) BHF-UCL PMID:11567634 MGI:2150820 Ensembl chr 1:1,168,935...1,171,337 JBrowse link
G TSC22D3 TSC22 domain family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9430225) Ensembl
MGI
TreeGrafter		 PMID:9430225 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:96,806,179...96,870,020
Ensembl chr  X:107,179,077...107,242,902 		JBrowse link
negative regulation of B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AURKB aurora kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8313913) Ensembl
MGI		 PMID:8313913 GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G FOXP1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173 		JBrowse link
G HSH2D hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (PMID:15569688) MGI PMID:15569688 NCBI chr19:15,629,688...15,643,636
Ensembl chr19:16,611,500...16,624,500 		JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9184696) MGI
Ensembl		 PMID:9184696 GO_REF:0000107 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:7736574) MGI PMID:7736574 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213 		JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) BHF-UCL PMID:15572028 MGI:4456946 NCBI chr13:90,886,095...90,917,724 JBrowse link
G NOC2L NOC2 like nucleolar associated transcriptional repressor involved_in ISO (PMID:20959462) UniProt PMID:20959462 Ensembl chr 1:843,551...857,535 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28747345) MGI
Ensembl		 PMID:28747345 GO_REF:0000107 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G PDCD1 programmed cell death 1 acts_upstream_of_or_within ISO (PMID:23636058) MGI PMID:23636058 NCBI chr12:130,849,353...130,858,776 JBrowse link
G SLC39A10 solute carrier family 39 member 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25074913) Ensembl
MGI		 PMID:25074913 GO_REF:0000107 NCBI chr2B:82,823,472...82,981,894
Ensembl chr2B:200,805,459...200,883,524 		JBrowse link
negative regulation of dendritic cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXL AXL receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,211,555...38,254,464
Ensembl chr19:46,719,615...46,761,747 		JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17267035) Ensembl
MGI		 PMID:17267035 GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G BCL2L1 BCL2 like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17267035) Ensembl
MGI		 PMID:17267035 GO_REF:0000107 NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 involved_in ISO (PMID:15059845) BHF-UCL PMID:15059845 NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr13:113,968,843...114,009,562 JBrowse link
G LOC103783591 leukocyte immunoglobulin-like receptor subfamily B member 1 involved_in ISO (PMID:18094328) UniProt PMID:18094328 NCBI chr19:51,561,376...51,578,564 JBrowse link
negative regulation of lymphocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8170972) Ensembl
MGI		 PMID:8170972 GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G FCMR Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) MGI PMID:15632112 NCBI chr 1:182,506,551...182,525,249
Ensembl chr 1:186,786,147...186,803,789 		JBrowse link
negative regulation of macrophage apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 involved_in ISO (MGI:3608189|PMID:16208318) BHF-UCL PMID:16208318 MGI:3608189 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 involved_in ISO (MGI:3608189|PMID:16208318) BHF-UCL PMID:16208318 MGI:3608189 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:25337654 RGD:12907499 NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773 		JBrowse link
G SELENOS selenoprotein S involved_in ISO (PMID:17210132) BHF-UCL PMID:17210132 NCBI chr15:79,995,678...80,002,159
Ensembl chr15:99,279,203...99,285,682 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO RGD PMID:21930713 RGD:10043116 NCBI chr 3:183,955,462...184,104,537
Ensembl chr 3:192,488,087...192,569,970 		JBrowse link
negative regulation of mast cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER1G Fc epsilon receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:12714518) MGI PMID:12714518 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213 		JBrowse link
G KITLG KIT ligand involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12714518) Ensembl
MGI		 PMID:12714518 GO_REF:0000107 NCBI chr12:86,036,501...86,124,274
Ensembl chr12:89,341,921...89,436,758 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:15947484) MGI PMID:15947484 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
negative regulation of mature B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14607964) Ensembl
MGI		 PMID:14607964 GO_REF:0000107 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in ISO (PMID:15878976) UniProt PMID:15878976 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G CD44 CD44 molecule (IN blood group) involved_in ISO (MGI:3773489|PMID:18056708) BHF-UCL PMID:18056708 MGI:3773489 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009 		JBrowse link
G CD74 CD74 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G MIF macrophage migration inhibitory factor involved_in ISO (MGI:3773489|PMID:18056708) BHF-UCL PMID:18056708 MGI:3773489 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009 		JBrowse link
negative regulation of neutrophil apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:22312020 RGD:7257693 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148 		JBrowse link
G FCGR2B Fc gamma receptor IIb ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:137,074,342...137,090,962
Ensembl chr 1:140,882,043...140,890,637 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:20844839 RGD:8655995 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18339802) Ensembl
MGI		 PMID:18339802 GO_REF:0000107 NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678 		JBrowse link
negative regulation of T cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within ISO (PMID:12717433) MGI PMID:12717433 NCBI chr14:79,795,262...79,898,472 JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7751019) Ensembl
MGI		 PMID:7751019 GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G BCL3 BCL3 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16832056) Ensembl
MGI		 PMID:16832056 GO_REF:0000107 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CD27 CD27 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9692890) Ensembl
MGI		 PMID:9692890 GO_REF:0000107 NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427 		JBrowse link
G DOCK8 dedicator of cytokinesis 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21969276) Ensembl
MGI		 PMID:21969276 GO_REF:0000107 NCBI chr 9:6,791...256,837
Ensembl chr 9:201,156...446,910 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18077788) Ensembl
MGI		 PMID:18077788 GO_REF:0000107 NCBI chr 8:39,108,310...39,123,611
Ensembl chr 8:36,617,312...36,632,352 		JBrowse link
G IL7R interleukin 7 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9215624) Ensembl
MGI		 PMID:9215624 GO_REF:0000107 NCBI chr 5:74,489,188...74,516,330
Ensembl chr 5:79,769,859...79,792,612 		JBrowse link
G PIP prolactin induced protein involved_in ISO (PMID:10072505) UniProt PMID:10072505 NCBI chr 7:135,127,479...135,135,117 JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900 		JBrowse link
G RAG1 recombination activating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18684012) Ensembl
MGI		 PMID:18684012 GO_REF:0000107 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
G SERPINB9 serpin family B member 9 acts_upstream_of_or_within ISO (PMID:16618603) MGI PMID:16618603 NCBI chr 6:2,709,188...2,725,592
Ensembl chr 6:2,812,815...2,827,932 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18684012) Ensembl
MGI		 PMID:18684012 GO_REF:0000107 NCBI chr 9:84,001,056...84,013,231
Ensembl chr 9:112,154,001...112,165,906 		JBrowse link
negative regulation of thymocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11067867), (PMID:16670300) Ensembl
MGI		 PMID:11067867 PMID:16670300 GO_REF:0000107 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within ISO (PMID:16670294) MGI PMID:16670294 NCBI chr14:79,795,262...79,898,472 JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:11046052) MGI PMID:11046052 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G EFNA1 ephrin A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16547242) Ensembl
MGI		 PMID:16547242 GO_REF:0000107 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15456877) Ensembl
MGI		 PMID:15456877 GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G JAK3 Janus kinase 3 involved_in ISO (MGI:3619195|PMID:9973401) BHF-UCL PMID:9973401 MGI:3619195 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964 		JBrowse link
G KIFAP3 kinesin associated protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10793158) Ensembl
MGI		 PMID:10793158 GO_REF:0000107 NCBI chr 1:145,410,755...145,564,248
Ensembl chr 1:149,127,548...149,280,831 		JBrowse link
G PTCRA pre T cell antigen receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728238) TreeGrafter
MGI		 PMID:15728238 GO_REF:0000118 NCBI chr 6:42,504,369...42,514,837
Ensembl chr 6:43,799,778...43,811,882 		JBrowse link
G RAG1 recombination activating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728238) Ensembl
MGI		 PMID:15728238 GO_REF:0000107 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (MGI:3694879|PMID:16148126) UniProt PMID:16148126 MGI:3694879 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15456877) Ensembl
MGI		 PMID:15456877 GO_REF:0000107 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    negative regulation of biological process 5460
      negative regulation of cellular process 5117
        negative regulation of programmed cell death 1010
          negative regulation of apoptotic process 978
            negative regulation of leukocyte apoptotic process 65
              negative regulation of dendritic cell apoptotic process 8
              negative regulation of lymphocyte apoptotic process + 44
              negative regulation of macrophage apoptotic process 6
              negative regulation of mast cell apoptotic process 4
              negative regulation of neutrophil apoptotic process 4
Path 2
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cell death 1962
        programmed cell death 1962
          apoptotic process 1884
            regulation of apoptotic process 1573
              negative regulation of apoptotic process 978
                negative regulation of leukocyte apoptotic process 65
                  negative regulation of dendritic cell apoptotic process 8
                  negative regulation of lymphocyte apoptotic process + 44
                  negative regulation of macrophage apoptotic process 6
                  negative regulation of mast cell apoptotic process 4
                  negative regulation of neutrophil apoptotic process 4
paths to the root