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Term:establishment of blood-retinal barrier
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Accession:GO:1990963 term browser browse the term
Definition:Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.
Synonyms:exact_synonym: establishment of blood-retina barrier
 related_synonym: establishment of BRB
 only_in_taxon: NCBITaxon:7742 ! Vertebrata

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establishment of blood-retinal barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:24985475 RGD:11062172 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Cdc45 cell division cycle 45 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:25323998) RGD PMID:25323998 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
PMID:25083995 GO_REF:0000107 MGI:5606223 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:2183279 (MGI:5606223|PMID:25083995) RGD PMID:25083995 MGI:5606223 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:5299216 (MGI:5606223|PMID:25083995) RGD PMID:25083995 MGI:5606223 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid NOT|involved_in ISO (MGI:5789479|PMID:27008858) RGD PMID:27008858 MGI:5789479 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO MGI:2676199 (MGI:6163329|PMID:29654250) RGD PMID:29654250 MGI:6163329 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19572
    developmental process 6914
      anatomical structure development 6442
        cell development 3237
          establishment of blood-retinal barrier 8
Path 2
Term Annotations click to browse term
  biological_process 19572
    developmental process 6914
      cellular developmental process 4644
        cell differentiation 4643
          cell development 3237
            establishment of blood-retinal barrier 8
paths to the root