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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular associated smooth muscle cell dedifferentiation
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Accession:GO:1990936 term browser browse the term
Definition:The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
Synonyms:exact_synonym: vascular smooth muscle cell dedifferentiation
 only_in_taxon: NCBITaxon:33208 ! Metazoa



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positive regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR214 microRNA mir-214 involved_in ISO (PMID:27144530) BHF-UCL PMID:27144530 NCBI chr 9:114,527,992...114,528,101
Ensembl chr 9:114,527,990...114,528,101
JBrowse link
G MIR221 microRNA mir-221 involved_in ISO (PMID:19088079) BHF-UCL PMID:19088079 NCBI chr  X:40,571,068...40,571,137
Ensembl chr  X:40,571,068...40,571,137
JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:8,986,462...9,007,435 JBrowse link
regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OLFM2 olfactomedin 2 involved_in ISO PMID:28062493 UniProt PMID:28062493 RGD:13441204 NCBI chr 2:68,734,078...68,807,207
Ensembl chr 2:68,734,081...68,807,191
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 17654
    developmental process 6659
      dedifferentiation 11
        cell dedifferentiation 11
          cell dedifferentiation involved in phenotypic switching 4
            vascular associated smooth muscle cell dedifferentiation 4
              negative regulation of vascular associated smooth muscle cell dedifferentiation 0
              positive regulation of vascular associated smooth muscle cell dedifferentiation 3
              regulation of vascular associated smooth muscle cell dedifferentiation + 4
paths to the root