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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA N1-methyladenosine dioxygenase activity
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Accession:GO:1990930 term browser browse the term
Definition:Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.
Synonyms:related_synonym: RNA N(1)-methyladenosine dioxygenase activity;   RNA N1-methyladenosine dioxygenase activity
 xref: EC:1.14.11.54;   RHEA:49516



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mRNA N1-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISS
ISO
GO_REF:0000024
(PMID:26863196), (PMID:26863410)
UniProt
RGD
PMID:26863196 PMID:26863410 GO_REF:0000024 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21088
    catalytic activity 6122
      demethylase activity 42
        oxidative RNA demethylase activity 5
          mRNA N1-methyladenosine dioxygenase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21088
    catalytic activity 6122
      oxidoreductase activity 868
        oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 244
          2-oxoglutarate-dependent dioxygenase activity 64
            oxidative RNA demethylase activity 5
              mRNA N1-methyladenosine dioxygenase activity 1
paths to the root