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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular detoxification
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Accession:GO:1990748 term browser browse the term
Definition:Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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cellular detoxification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 (JR blood group) involved_in ISO (PMID:9861027) GO_Central PMID:9861027 NCBI chrNW_004955474:12,365,903...12,408,715 JBrowse link
G Aifm2 AIF family member 2 involved_in ISO (PMID:35922516) UniProt PMID:35922516 NCBI chrNW_004955437:21,111,298...21,126,487
Ensembl chrNW_004955437:21,110,798...21,126,482
JBrowse link
G Aqp8 aquaporin 8 involved_in ISO (PMID:34292591) UniProt PMID:34292591 NCBI chrNW_004955493:3,550,697...3,558,875
Ensembl chrNW_004955493:3,550,120...3,559,206
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 involved_in ISO (PMID:20884751) FlyBase PMID:20884751 RGD:407430016 NCBI chrNW_004955438:1,218,990...1,231,407
Ensembl chrNW_004955438:1,219,018...1,231,287
JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 involved_in ISO (PMID:25158856) UniProt PMID:25158856 NCBI chrNW_004955457:5,055,774...5,087,570
Ensembl chrNW_004955457:5,055,412...5,087,629
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:18056989) UniProt PMID:18056989 NCBI chrNW_004955437:5,940,825...5,945,367
Ensembl chrNW_004955437:5,942,106...5,945,431
JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:22042847) ParkinsonsUK-UCL PMID:22042847 NCBI chrNW_004955406:41,452,733...41,468,467
Ensembl chrNW_004955406:41,462,534...41,468,948
JBrowse link
G Rab40b RAB40B, member RAS oncogene family involved_in ISO (PMID:22042847) ParkinsonsUK-UCL PMID:22042847 NCBI chrNW_004955506:480,236...509,038
Ensembl chrNW_004955506:479,516...512,362
JBrowse link
G Slc22a2 solute carrier family 22 member 2 involved_in ISO (PMID:20477935)
PMID:20924140
(PMID:22806583), (PMID:24291757), (PMID:9687576)
ARUK-UCL PMID:9687576 PMID:20477935 PMID:20924140 PMID:22806583 PMID:24291757 RGD:30309940 RGD:30309941 NCBI chrNW_004955439:20,567,241...20,608,281
Ensembl chrNW_004955439:20,567,212...20,609,105
JBrowse link
G Slc22a3 solute carrier family 22 member 3 involved_in ISO (PMID:22806583), (PMID:24291757) ARUK-UCL PMID:22806583 PMID:24291757 NCBI chrNW_004955439:20,367,324...20,476,891
Ensembl chrNW_004955439:20,367,333...20,476,891
JBrowse link
G Slc29a4 solute carrier family 29 member 4 involved_in ISO (PMID:23255610) ARUK-UCL PMID:23255610 NCBI chrNW_004955460:10,155,916...10,181,974
Ensembl chrNW_004955460:10,155,899...10,181,974
JBrowse link
cellular detoxification of aldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 involved_in ISO PMID:25152401
(PMID:22820017)
UniProt PMID:22820017 PMID:25152401 RGD:13838799 NCBI chrNW_004955464:12,715,238...12,729,034
Ensembl chrNW_004955464:12,714,717...12,729,662
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:28993701) UniProt PMID:28993701 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Rdh11 retinol dehydrogenase 11 involved_in ISO (PMID:12807874) UniProt PMID:12807874 NCBI chrNW_004955466:2,506,641...2,521,506
Ensembl chrNW_004955466:2,508,338...2,520,903
JBrowse link
G Rdh12 retinol dehydrogenase 12 involved_in ISO (PMID:19686838)
(PMID:22621924)
UniProt PMID:19686838 PMID:22621924 NCBI chrNW_004955466:2,473,145...2,485,779
Ensembl chrNW_004955466:2,473,096...2,487,623
JBrowse link
cellular detoxification of cadmium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in ISO (PMID:31053883) UniProt PMID:31053883 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172
JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in ISO (PMID:17932044) BHF-UCL PMID:17932044 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Slc39a8 solute carrier family 39 member 8 involved_in ISO (PMID:27466201) UniProt PMID:27466201 NCBI chrNW_004955496:6,016,727...6,106,965
Ensembl chrNW_004955496:6,040,029...6,109,907
JBrowse link
cellular detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase involved_in ISO (PMID:18379038) ComplexPortal PMID:18379038 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
cellular detoxification of methylglyoxal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:28993701) UniProt PMID:28993701 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
cellular detoxification of nitrogen compound term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm3 glutathione S-transferase mu 3 involved_in ISO (PMID:8373352) BHF-UCL PMID:8373352 NCBI chrNW_004955435:13,253,947...13,256,965
Ensembl chrNW_004955435:13,253,947...13,256,965
JBrowse link
cellular oxidant detoxification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambp alpha-1-microglobulin/bikunin precursor involved_in ISO (PMID:22096585), (PMID:23642167) UniProt PMID:22096585 PMID:23642167 NCBI chrNW_004955419:13,478,904...13,492,329
Ensembl chrNW_004955419:13,478,552...13,492,327
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase ISO RGD PMID:22198343 RGD:13513982 NCBI chrNW_004955446:18,685,511...18,778,024
Ensembl chrNW_004955446:18,685,516...18,778,024
JBrowse link
G Prdx6 peroxiredoxin 6 involved_in ISO (PMID:10893423) CAFA PMID:10893423 NCBI chrNW_004955406:13,717,267...13,728,216
Ensembl chrNW_004955406:13,717,267...13,728,216
JBrowse link
G Selenot selenoprotein T involved_in ISO PMID:26866473 UniProt PMID:26866473 RGD:12793008 NCBI chrNW_004955448:1,794,959...1,814,282
Ensembl chrNW_004955448:1,795,043...1,812,930
JBrowse link
G Sesn1 sestrin 1 involved_in ISO (PMID:15105503) UniProt PMID:15105503 NCBI chrNW_004955411:34,033,986...34,051,171
Ensembl chrNW_004955411:34,032,490...34,139,822
JBrowse link
G Sesn2 sestrin 2 involved_in
NOT|involved_in
ISO (PMID:26612684)
(PMID:15105503)
(PMID:19113821)
UniProt PMID:15105503 PMID:19113821 PMID:26612684 NCBI chrNW_004955452:7,392,644...7,417,204
Ensembl chrNW_004955452:7,393,007...7,417,304
JBrowse link
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:28596309) UniProt PMID:28596309 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule (CD36 blood group) involved_in ISO (PMID:20978343) BHF-UCL PMID:20978343 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chrNW_004955418:29,274,170...29,283,028 JBrowse link
G Fbln5 fibulin 5 involved_in ISO (PMID:15528465) BHF-UCL PMID:15528465 NCBI chrNW_004955438:14,073,927...14,144,644
Ensembl chrNW_004955438:14,071,410...14,145,070
JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:20978343) BHF-UCL PMID:20978343 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in ISO (PMID:16945374) HGNC-UCL PMID:16945374 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO (PMID:16371425) MGI PMID:16371425 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G Cygb cytoglobin involved_in ISO (PMID:34930834) UniProt PMID:34930834 NCBI chrNW_004955506:5,766,006...5,775,722
Ensembl chrNW_004955506:5,766,006...5,775,784
JBrowse link
G Fancc FA complementation group C acts_upstream_of_or_within ISO (PMID:11493445) MGI PMID:11493445 NCBI chrNW_004955422:22,031,825...22,246,478
Ensembl chrNW_004955422:22,032,258...22,247,044
JBrowse link
G Mb myoglobin involved_in ISO (PMID:34679218) UniProt PMID:34679218 NCBI chrNW_004955405:43,215,404...43,221,606
Ensembl chrNW_004955405:43,215,007...43,222,052
JBrowse link
G Mpo myeloperoxidase acts_upstream_of_or_within ISO (PMID:10085024) MGI PMID:10085024 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Nos3 nitric oxide synthase 3 involved_in ISO (PMID:19666465) BHF-UCL PMID:19666465 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in ISO (PMID:15102952) UniProt PMID:15102952 NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24567322) ParkinsonsUK-UCL PMID:24567322 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885
JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO (PMID:16170382)
(PMID:16880205)
MGI PMID:16170382 PMID:16880205 NCBI chrNW_004955464:12,761,390...12,773,413
Ensembl chrNW_004955464:12,761,401...12,773,146
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in ISO (PMID:20978343) BHF-UCL PMID:20978343 NCBI chrNW_004955415:31,880,801...31,884,453
Ensembl chrNW_004955415:31,880,588...31,884,778
JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in
ISO (PMID:10436316), (PMID:10471451), (PMID:11493445), (PMID:8673102)
(PMID:11493445)
(PMID:12433839), (PMID:17448893)
(PMID:9516486), (PMID:9788901)
(PMID:10679476)
(PMID:16254550), (PMID:24567322)
MGI
UniProt
RGD
PMID:8673102 PMID:9516486 PMID:9788901 PMID:10436316 PMID:10471451 More... RGD:1601266 RGD:634854 RGD:8655968 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within
involved_in
ISO (PMID:16873728)
(PMID:16179351)
MGI
BHF-UCL
RGD
PMID:12107766 PMID:15642720 PMID:16179351 PMID:16873728 PMID:19439219 RGD:2291939 RGD:2291946 RGD:2317387 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12559
    detoxification 55
      cellular detoxification 44
        cellular detoxification of acetone 0
        cellular detoxification of aldehyde + 5
        cellular detoxification of fluoride 0
        cellular detoxification of metal ion + 3
        cellular detoxification of nitrogen compound 1
        cellular detoxification of sulfide 0
        cellular oxidant detoxification + 25
        toxic metabolite repair 0
Path 2
Term Annotations click to browse term
  biological_process 12559
    cellular process 11998
      cellular response to stimulus 5341
        cellular response to chemical stimulus 2103
          cellular response to toxic substance 65
            cellular detoxification 44
              cellular detoxification of acetone 0
              cellular detoxification of aldehyde + 5
              cellular detoxification of fluoride 0
              cellular detoxification of metal ion + 3
              cellular detoxification of nitrogen compound 1
              cellular detoxification of sulfide 0
              cellular oxidant detoxification + 25
              toxic metabolite repair 0
paths to the root