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ONTOLOGY REPORT - ANNOTATIONS


Term:beta-catenin-ICAT complex
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Accession:GO:1990711 term browser browse the term
Definition:Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.
Comment:An example of this is Catenin beta-1 in human (UniProt symbol P35222) in PMID:12408824 (inferred from physical interaction).
Synonyms:exact_synonym: CTNNB1-CTNNBIP1 complex
 xref: IntAct:EBI-10691252;   IntAct:EBI-10705284


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  cellular_component 23187
    cellular anatomical entity 19110
      nucleoplasm 3451
        beta-catenin-ICAT complex 0
Path 2
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  cellular_component 23187
    cellular anatomical entity 19110
      organelle 12867
        membrane-bounded organelle 11620
          intracellular membrane-bounded organelle 10882
            nucleus 7265
              nuclear lumen 4324
                nucleoplasm 3451
                  beta-catenin-ICAT complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.