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ONTOLOGY REPORT - ANNOTATIONS

Term:phospholamban complex
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Accession:GO:1990629 term browser browse the term
Definition:A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.
Comment:An example of this is PLN in human (UniProt symbol P26678) in PMID:16043693 (inferred from direct assay).
Synonyms:exact_synonym: cardiac phospholamban complex
 related_synonym: cardiac PLB complex;   cardiac PLN complex


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  cellular_component 21392
    protein-containing complex 6987
      endoplasmic reticulum protein-containing complex 152
        phospholamban complex 0
Path 2
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  cellular_component 21392
    cellular anatomical entity 21234
      intracellular anatomical structure 15673
        intracellular organelle 13898
          intracellular membrane-bounded organelle 12331
            endoplasmic reticulum 1933
              endoplasmic reticulum subcompartment 1080
                endoplasmic reticulum membrane 1070
                  sarcoplasmic reticulum membrane 37
                    phospholamban complex 0
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