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Term:ESCRT IV complex
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Accession:GO:1990621 term browser browse the term
Definition:An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.
Synonyms:exact_synonym: ESCRT-IV
 narrow_synonym: VPS4A-VPS4B;   VPS4A/B complex
 related_synonym: Vps4 complex;   Vta1-Vps4 complex;   vacuolar protein sorting-associated complex
 xref: IntAct:EBI-11565638

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  cellular_component 20610
    protein-containing complex 6105
      membrane protein complex 1254
        ESCRT IV complex 0
Path 2
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  cellular_component 20610
    cellular anatomical entity 20359
      organelle 13271
        membrane-bounded organelle 11457
          vesicle 2065
            intracellular vesicle 1906
              cytoplasmic vesicle 1900
                endosome 868
                  endosome membrane 347
                    ESCRT IV complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.