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ONTOLOGY REPORT - ANNOTATIONS


Term:IRE1-TRAF2-ASK1 complex
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Accession:GO:1990604 term browser browse the term
Definition:A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
Synonyms:related_synonym: ERN1-TRAF2-ASK1 complex



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IRE1-TRAF2-ASK1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ern1 endoplasmic reticulum to nucleus signaling 1 part_of IBA
ISO
PMID:21873635
(PMID:23000344)
RGD PMID:23000344 PMID:21873635 RGD:13792537 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 part_of IBA
ISO
PMID:21873635
(MGI:5616327|PMID:12050113)
RGD PMID:12050113 PMID:21873635 MGI:5616327, RGD:13792537 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 part_of ISO (PMID:12050113), (PMID:23000344) RGD PMID:12050113 PMID:23000344 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Traf2 Tnf receptor-associated factor 2 part_of ISO
ISS
(PMID:23000344)
GO_REF:0000024
(MGI:5616327|PMID:12050113)
RGD
ParkinsonsUK-UCL
PMID:12050113 PMID:23000344 GO_REF:0000024 MGI:5616327 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20516
    protein-containing complex 6324
      endoplasmic reticulum protein-containing complex 140
        IRE1-TRAF2-ASK1 complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20516
    cellular anatomical entity 20273
      organelle 13515
        intracellular organelle 13131
          intracellular membrane-bounded organelle 11558
            endoplasmic reticulum 1822
              endoplasmic reticulum subcompartment 1006
                endoplasmic reticulum membrane 997
                  IRE1-TRAF2-ASK1 complex 4
paths to the root