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ONTOLOGY REPORT - ANNOTATIONS

Term:Dom34-Hbs1 complex
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Accession:GO:1990533 term browser browse the term
Definition:A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.


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Dom34-Hbs1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbs1l HBS1-like translational GTPase part_of ISO
ISS		 (PMID:27863242)
GO_REF:0000024		 RGD
UniProt		 PMID:27863242 GO_REF:0000024 NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor part_of ISO
ISS		 (PMID:27863242)
GO_REF:0000024		 RGD
UniProt		 PMID:27863242 GO_REF:0000024 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      Dom34-Hbs1 complex 2
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