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Term:dense core granule maturation
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Accession:GO:1990502 term browser browse the term
Definition:Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.
Synonyms:exact_synonym: dense core vesicle maturation

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dense core granule maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baiap3 BAI1-associated protein 3 involved_in ISO (PMID:28626000) RGD PMID:28626000 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N involved_in ISO UniProtKB:Q6P4T1 (PMID:24843546) RGD PMID:24843546 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Snx19 sorting nexin 19 involved_in
ISO UniProtKB:Q6P4T1 (PMID:24843546)
RGD PMID:24843546 MGI:5605377 NCBI chr 8:28,829,881...28,867,600
Ensembl chr 8:28,829,886...28,867,061
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      developmental maturation 363
        secretory granule maturation 4
          dense core granule maturation 3
Path 2
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      cellular component organization or biogenesis 6736
        cellular component organization 6486
          organelle organization 3987
            vesicle organization 308
              secretory granule organization 47
                secretory granule maturation 4
                  dense core granule maturation 3
paths to the root