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Term:mitochondrion-endoplasmic reticulum membrane tethering
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Accession:GO:1990456 term browser browse the term
Definition:The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.
Synonyms:exact_synonym: mitochondrion-ER attachment;   mitochondrion-ER membrane tethering;   mitochondrion-ER tethering;   mitochondrion-endoplasmic reticulum attachment;   mitochondrion-endoplasmic reticulum tethering

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mitochondrion-endoplasmic reticulum membrane tethering term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcyl1 adenosylhomocysteinase-like 1 ISO
PMID:27995898 GO_REF:0000024 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Pacs2 phosphofurin acidic cluster sorting protein 2 ISO (PMID:15692567) RGD PMID:15692567 NCBI chr 6:137,824,136...137,889,144
Ensembl chr 6:137,824,213...137,887,418
JBrowse link
G Pdzd8 PDZ domain containing 8 ISO (PMID:29097544)
RGD PMID:29097544 MGI:6094720 NCBI chr 1:280,458,041...280,515,650
Ensembl chr 1:280,458,041...280,515,650
JBrowse link
G Psen2 presenilin 2 ISO (PMID:21285369) RGD PMID:21285369 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          mitochondrion-endoplasmic reticulum membrane tethering 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular localization 2966
        organelle localization 573
          organelle localization by membrane tethering 82
            mitochondrion-endoplasmic reticulum membrane tethering 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.