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ONTOLOGY REPORT - ANNOTATIONS

Term:L-type voltage-gated calcium channel complex
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Accession:GO:1990454 term browser browse the term
Definition:A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.
Comment:Examples of this are CACNA1S, CACNA2D1, CACNB1, CACNG1 in rabbit (UniProt symbol P07293, P13806, P19517 and P19518) in PMID:12946355 (inferred from direct assay).
Synonyms:narrow_synonym: cardiac muscle L-type voltage-gated calcium channel complex;   skeletal muscle L-type voltage-gated calcium channel complex


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L-type voltage-gated calcium channel complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C part_of IDA
ISO
ISS		 PMID:15170217
(PMID:15454078)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:15454078 PMID:15170217 GO_REF:0000024, RGD:11558004 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D part_of ISO
IEA		 (PMID:1309651)
GO_REF:0000107		 RGD
Ensembl		 PMID:1309651 GO_REF:0000107 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 part_of IDA
ISO
IEA
IBA		 PMID:25527503
(PMID:1309651)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:1309651 PMID:25527503 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:11059598 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 part_of ISO
IDA
IEA		 (PMID:1309651)
PMID:26680202
GO_REF:0000107		 RGD
Ensembl		 PMID:1309651 PMID:26680202 GO_REF:0000107, RGD:12907551 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 part_of IDA
IMP		 PMID:15170217
PMID:25527503
PMID:10666413		 UniProt
BHF-UCL		 PMID:15170217 PMID:25527503 PMID:10666413 RGD:11558004, RGD:11059598, RGD:13673808 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 part_of IMP
ISS
IBA
IEA		 PMID:9049149
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118		 UniProt
GO_Central
TreeGrafter		 PMID:9049149 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118, RGD:69791 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 part_of ISS
ISO		 GO_REF:0000024
(PMID:21127204)		 UniProt
RGD		 PMID:21127204 GO_REF:0000024 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126 		JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 part_of ISO
ISS
IBA		 (PMID:21127204)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:21127204 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 part_of ISO
ISS		 (PMID:21127204)
GO_REF:0000024		 RGD
UniProt		 PMID:21127204 GO_REF:0000024 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 part_of ISS
ISO		 GO_REF:0000024
(MGI:6164122|PMID:21127204)		 UniProt
RGD		 PMID:21127204 GO_REF:0000024 MGI:6164122 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      T-tubule 75
        L-type voltage-gated calcium channel complex 11
Path 2
Term Annotations click to browse term
  cellular_component 21392
    cellular anatomical entity 21234
      membrane 10503
        membrane protein complex 1451
          transmembrane transporter complex 472
            monoatomic ion channel complex 340
              cation channel complex 208
                calcium channel complex 70
                  voltage-gated calcium channel complex 46
                    L-type voltage-gated calcium channel complex 11
paths to the root