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ONTOLOGY REPORT - ANNOTATIONS

Term:Parkin-FBXW7-Cul1 ubiquitin ligase complex
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Accession:GO:1990452 term browser browse the term
Definition:A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.
Synonyms:exact_synonym: PARK2-FBXW7-Cul1 complex;   PRKN-FBXW7-Cul1 complex;   Parkin-FBXW7-Cul1 protein complex;   Parkin/Cul1/F-box protein complex
 narrow_synonym: Parkin-HSel-10-Cullin-1 complex

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Parkin-FBXW7-Cul1 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cul1 cullin 1 part_of ISO (PMID:12628165) ParkinsonsUK-UCL PMID:12628165 NCBI chrNW_004955491:4,165,400...4,212,483
Ensembl chrNW_004955491:4,165,561...4,212,054 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 part_of ISO (PMID:12628165) ParkinsonsUK-UCL PMID:12628165 NCBI chrNW_004955471:6,852,459...7,026,590
Ensembl chrNW_004955471:6,848,101...6,955,881 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase part_of ISO (PMID:12628165) ParkinsonsUK-UCL PMID:12628165 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12554
    protein-containing complex 4416
      intracellular protein-containing complex 730
        ubiquitin ligase complex 232
          Parkin-FBXW7-Cul1 ubiquitin ligase complex 3
Path 2
Term Annotations click to browse term
  cellular_component 12554
    protein-containing complex 4416
      catalytic complex 1326
        transferase complex 662
          ubiquitin ligase complex 232
            Parkin-FBXW7-Cul1 ubiquitin ligase complex 3
paths to the root