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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:intrinsic apoptotic signaling pathway in response to nitrosative stress
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Accession:GO:1990442 term browser browse the term
Definition:The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
Synonyms:exact_synonym: nitrosative stress-induced intrinsic apoptotic signaling pathway
 related_synonym: nitrosative stress-induced apoptosis

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intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA damage inducible transcript 3 involved_in ISO (MGI:5784990|PMID:14752510) ParkinsonsUK-UCL PMID:14752510 MGI:5784990 NCBI chrNW_004936646:1,665,019...1,669,212 JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:1,599,883...1,611,302
Ensembl chrNW_004936524:1,599,913...1,610,682 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15969
    response to stimulus 8553
      response to stress 3651
        response to nitrosative stress 10
          cellular response to nitrosative stress 6
            intrinsic apoptotic signaling pathway in response to nitrosative stress 3
              negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 2
              positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 0
              regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 15969
    biological regulation 11154
      regulation of biological process 10818
        regulation of cellular process 10346
          signal transduction 5702
            apoptotic signaling pathway 622
              intrinsic apoptotic signaling pathway 315
                intrinsic apoptotic signaling pathway in response to nitrosative stress 3
                  negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 2
                  positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway 0
                  regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway + 2
paths to the root