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ONTOLOGY REPORT - ANNOTATIONS


Term:ryanodine receptor complex
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Accession:GO:1990425 term browser browse the term
Definition:A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.
Comment:An example of this is RyR1 in rabbit (P11716) in PMID:2550460 (inferred from electron microscopy).
Synonyms:related_synonym: RyR


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ryanodine receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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G Ryr1 ryanodine receptor 1 part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
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Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20010
    protein-containing complex 6011
      endoplasmic reticulum protein-containing complex 139
        ryanodine receptor complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20010
    cellular anatomical entity 19714
      membrane 9924
        intrinsic component of membrane 6740
          integral component of membrane 6593
            transmembrane transporter complex 401
              ion channel complex 297
                cation channel complex 230
                  calcium channel complex 65
                    voltage-gated calcium channel complex 42
                      ryanodine receptor complex 2
paths to the root