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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA repair complex
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Accession:GO:1990391 term browser browse the term
Definition:A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
Synonyms:exact_synonym: DNA damage repair complex
 narrow_synonym: WHY1 complex
 xref: IntAct:EBI-16426962


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DNA repair complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Phf21a PHD finger protein 21A ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 3:81,099,765...81,271,841
Ensembl chr 3:81,134,505...81,271,849
JBrowse link
G Rcor1 REST corepressor 1 ISO (PMID:24217620) RGD PMID:24217620 NCBI chr 6:135,475,470...135,552,155
Ensembl chr 6:135,513,650...135,548,201
Ensembl chr 6:135,513,650...135,548,201
JBrowse link
G Rnf168 ring finger protein 168 ISO (MGI:MGI:5562615|PMID:24217620) RGD PMID:24217620 MGI:MGI:5562615 NCBI chr11:71,721,242...71,743,421
Ensembl chr11:71,721,250...71,743,421
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO (MGI:MGI:5562615|PMID:24217620) RGD PMID:24217620 MGI:MGI:5562615 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
DNA-dependent protein kinase-DNA ligase 4 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lig4 DNA ligase 4 ISO
IBA
(MGI:MGI:3052572|PMID:15194694)
PMID:21873635
(PMID:15194694)
RGD PMID:15194694, PMID:21873635 MGI:MGI:3052572, RGD:13792537 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:15194694) RGD PMID:15194694 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO
IBA
(PMID:15194694)
PMID:21873635
(MGI:MGI:3052572|PMID:15194694)
RGD PMID:15194694, PMID:21873635 MGI:MGI:3052572, RGD:13792537 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 TAS RGD PMID:11966321 RGD:727219 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
ERCC4-ERCC1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO
IBA
(PMID:14690602), (PMID:17055345)
PMID:21873635
RGD PMID:14690602, PMID:17055345, PMID:21873635 RGD:13792537 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO (PMID:14690602), (PMID:17055345) RGD PMID:14690602, PMID:17055345 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit colocalizes_with ISO (PMID:19595721), (PMID:19596235), (PMID:19596236) RGD PMID:19595721, PMID:19596235, PMID:19596236 NCBI chr10:11,787,756...11,808,326
Ensembl chr10:11,786,121...11,807,928
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO (MGI:MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:MGI:3758502 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO (MGI:MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:MGI:3758502 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
mismatch repair complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mlh3 mutL homolog 3 ISO
IBA
(MGI:MGI:5315075|PMID:22164254)
PMID:21873635
RGD PMID:22164254, PMID:21873635 MGI:MGI:5315075, RGD:13792537 NCBI chr 6:109,059,386...109,095,876
Ensembl chr 6:109,059,341...109,095,557
JBrowse link
G Msh2 mutS homolog 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh3 mutS homolog 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Msh6 mutS homolog 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:53,120,656...53,206,520
Ensembl chr 9:53,120,656...53,206,516
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
MutLalpha complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:3653556|PMID:16713580), (MGI:MGI:5315075|PMID:22164254)
Ensembl
RGD
PMID:16713580, PMID:22164254, PMID:21873635 GO_REF:0000107, MGI:MGI:3653556, MGI:MGI:5315075, RGD:13792537 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO
IBA
(MGI:MGI:3653556|PMID:16713580)
PMID:21873635
RGD PMID:16713580, PMID:21873635 MGI:MGI:3653556, RGD:13792537 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
MutSalpha complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msh2 mutS homolog 2 ISO
IBA
IEA
ISS
(MGI:MGI:3653556|PMID:16713580)
PMID:21873635
(PMID:23622243), (PMID:8942985)
GO_REF:0000104
GO_REF:0000024
RGD
UniProt
PMID:8942985, PMID:16713580, PMID:23622243, PMID:21873635 GO_REF:0000024, GO_REF:0000104, MGI:MGI:3653556, RGD:13792537 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh4 mutS homolog 4 IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:260,057,708...260,108,897
Ensembl chr 2:260,057,855...260,108,897
JBrowse link
G Msh6 mutS homolog 6 ISO
IBA
(MGI:MGI:3653556|PMID:16713580)
PMID:21873635
(PMID:23622243), (PMID:8942985)
RGD PMID:8942985, PMID:16713580, PMID:23622243, PMID:21873635 MGI:MGI:3653556, RGD:13792537 NCBI chr 6:11,644,565...11,662,389
Ensembl chr 6:11,644,578...11,662,499
JBrowse link
MutSbeta complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msh2 mutS homolog 2 ISO
IBA
IEA
(PMID:8942985)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8942985, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh3 mutS homolog 3 ISO
IBA
(PMID:8942985)
PMID:21873635
RGD PMID:8942985, PMID:21873635 RGD:13792537 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
nonhomologous end joining complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dclre1c DNA cross-link repair 1C ISO
ISS
(PMID:25941166)
GO_REF:0000024
RGD
UniProt
PMID:25941166 GO_REF:0000024 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Lig4 DNA ligase 4 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Nhej1 nonhomologous end-joining factor 1 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20383123), (PMID:25941166)
UniProt
RGD
PMID:20383123, PMID:25941166, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:82,230,230...82,327,923
Ensembl chr 9:82,230,232...82,327,534
JBrowse link
G Paxx PAXX, non-homologous end joining factor ISO
IBA
(PMID:25670504), (PMID:25941166)
PMID:21873635
RGD PMID:25670504, PMID:25941166, PMID:21873635 RGD:13792537 NCBI chr 3:2,678,987...2,681,668
Ensembl chr 3:2,678,956...2,680,622
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO (PMID:20383123), (PMID:25941166) RGD PMID:20383123, PMID:25941166 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
nucleotide-excision repair complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO (PMID:3290851), (PMID:7559382), (PMID:8197175) RGD PMID:3290851, PMID:7559382, PMID:8197175 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO (PMID:10644440) RGD PMID:10644440 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease ISO (PMID:11259578) RGD PMID:11259578 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit ISO
IBA
(PMID:12732143)
PMID:21873635
RGD PMID:12732143, PMID:21873635 RGD:13792537 NCBI chr 2:39,434,617...39,473,392
Ensembl chr 2:39,434,634...39,472,017
JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit ISO (PMID:20713449) RGD PMID:20713449 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO (PMID:11259578) RGD PMID:11259578 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
nucleotide-excision repair factor 1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC117889.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:975,697...1,003,352 JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO
IBA
(PMID:10413517)
PMID:21873635
RGD PMID:10413517, PMID:21873635 RGD:13792537 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO
IBA
(PMID:10413517)
PMID:21873635
RGD PMID:10413517, PMID:21873635 RGD:13792537 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
nucleotide-excision repair factor 2 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xpc XPC complex subunit, DNA damage recognition and repair factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
nucleotide-excision repair factor 3 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:25,037,668...25,068,380
Ensembl chr18:25,037,625...25,068,389
JBrowse link
Shu complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Swsap1 SWIM-type zinc finger 7 associated protein 1 ISO
IBA
(PMID:21965664)
PMID:21873635
RGD PMID:21965664, PMID:21873635 RGD:13792537 NCBI chr 8:22,966,752...22,969,280
Ensembl chr 8:22,966,561...22,969,459
JBrowse link
G Zswim7 zinc finger, SWIM-type containing 7 ISO
IBA
(PMID:21965664)
PMID:21873635
RGD PMID:21965664, PMID:21873635 RGD:13792537 NCBI chr10:48,587,117...48,599,208
Ensembl chr10:48,587,119...48,599,208
JBrowse link
XPC complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cetn2 centrin 2 ISO (PMID:11279143) RGD PMID:11279143 NCBI chr  X:152,927,852...152,933,095
Ensembl chr  X:152,927,718...152,932,953
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein ISO
ISS
(PMID:11279143)
GO_REF:0000024
RGD
UniProt
PMID:11279143 GO_REF:0000024 NCBI chr 5:72,103,704...72,141,701
Ensembl chr 5:72,103,704...72,141,700
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor IBA
ISO
PMID:21873635
(PMID:11279143), (PMID:31527837)
RGD PMID:11279143, PMID:31527837, PMID:21873635 RGD:13792537 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6105
      DNA repair complex 37
        Sad1-Kms1 LINC complex 0
        Shu complex 2
        excinuclease repair complex 0
        mismatch repair complex + 8
        nonhomologous end joining complex + 8
        nucleotide-excision repair complex + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.