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Term:sumoylated E2 ligase complex
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Accession:GO:1990356 term browser browse the term
Definition:A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase.
Comment:An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).

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sumoylated E2 ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube2i ubiquitin-conjugating enzyme E2I part_of ISO (PMID:15660128) RGD PMID:15660128 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
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  cellular_component 19309
    protein-containing complex 5988
      catalytic complex 1707
        sumoylated E2 ligase complex 1
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