Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:sumoylated E2 ligase complex
go back to main search page
Accession:GO:1990356 term browser browse the term
Definition:A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase.
Comment:An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).
Synonyms:xref: IntAct:EBI-9347978


show annotations for term's descendants           Sort by:
 
sumoylated E2 ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube2i ubiquitin-conjugating enzyme E2I part_of ISO (PMID:15660128) RGD PMID:15660128 NCBI chr10:14,618,615...14,639,274
Ensembl chr10:14,620,531...14,630,151
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20142
    protein-containing complex 6031
      sumoylated E2 ligase complex 1
paths to the root