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ONTOLOGY REPORT - ANNOTATIONS


Term:Atg1/ULK1 kinase complex
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Accession:GO:1990316 term browser browse the term
Definition:A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
Synonyms:exact_synonym: ATG1 kinase complex;   ATG1-ATG13 complex;   ATG1/ULK1 signaling complex;   Atg1p signalling complex;   ULK complex;   ULK1 complex;   ULK1 signaling complex;   ULK1-ATG13-FIP200 complex;   ULK1-ATG13-RB1CC1 complex;   autophagy-initiation complex
 alt_id: GO:0034273;   GO:0070969


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Atg1/ULK1 kinase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg13 autophagy related 13 part_of ISO
IBA
UniProtKB:O75385|UniProtKB:Q8TDY2 (PMID:19211835)
UniProtKB:O70405|UniProtKB:Q9ESK9 (MGI:3849242|PMID:19258318), (MGI:4365321|PMID:19211835)
PMID:21873635
RGD PMID:19211835 PMID:19258318, PMID:21873635 MGI:3849242 MGI:4365321, RGD:13792537 NCBI chr 3:80,580,549...80,614,554
Ensembl chr 3:80,581,247...80,601,410
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 part_of IBA
ISO
PMID:21873635
UniProtKB:O70405|UniProtKB:Q91YI1 (MGI:3849242|PMID:19258318), (MGI:4365321|PMID:19211835)
UniProtKB:Q8TDY2 (PMID:19211835)
RGD PMID:19211835 PMID:19258318, PMID:21873635 MGI:3849242 MGI:4365321, RGD:13792537 NCBI chr 5:13,033,918...13,097,369
Ensembl chr 5:13,033,918...13,097,341
JBrowse link
G RGD1359108 similar to RIKEN cDNA 3110043O21 colocalizes_with
part_of
ISO
IEA
ISS
(PMID:27193190)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:27193190 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:50,666,444...50,691,523
Ensembl chr 5:50,668,040...50,684,409
JBrowse link
G Sesn2 sestrin 2 part_of ISO GO:1990316 (PMID:25040165) RGD PMID:25040165 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit colocalizes_with
part_of
ISO (PMID:27193190)
(PMID:28195531)
RGD PMID:27193190 PMID:28195531 NCBI chr10:47,019,326...47,026,465
Ensembl chr10:47,018,974...47,026,465
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 colocalizes_with
part_of
ISO
IEA
(PMID:24603492)
GO_REF:0000107
RGD
Ensembl
PMID:24603492 GO_REF:0000107 NCBI chr 9:1,144,641...1,747,732
Ensembl chr 9:1,145,700...1,746,397
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 part_of ISO UniProtKB:Q8TDY2 (PMID:19211835)
UniProtKB:Q91YI1|UniProtKB:Q9ESK9 (MGI:3849242|PMID:19258318), (MGI:4365321|PMID:19211835)
RGD PMID:19211835 PMID:19258318 MGI:3849242 MGI:4365321 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Wdr41 WD repeat domain 41 colocalizes_with ISO (PMID:27193190) RGD PMID:27193190 NCBI chr 2:24,668,108...24,717,280
Ensembl chr 2:24,668,116...24,717,267
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20138
    cellular anatomical entity 19840
      cytoplasm 11424
        Atg1/ULK1 kinase complex 8
Path 2
Term Annotations click to browse term
  cellular_component 20138
    protein-containing complex 6037
      catalytic complex 1457
        transferase complex 800
          transferase complex, transferring phosphorus-containing groups 259
            protein kinase complex 104
              serine/threonine protein kinase complex 86
                Atg1/ULK1 kinase complex 8
paths to the root