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Term:paranodal junction maintenance
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Accession:GO:1990227 term browser browse the term
Definition:The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
Synonyms:exact_synonym: axoglial septate junction maintenance;   paranodal axoglial junction maintenance;   paranodal septate maintenance

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paranodal junction maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Whrn whirlin involved_in IEA
PMID:24011083 GO_REF:0000107 MGI:5516521 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223
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  biological_process 19494
    cellular process 18342
      cellular component organization or biogenesis 6483
        cellular component organization 6237
          cell junction organization 798
            cell junction maintenance 55
              cell-cell junction maintenance 22
                paranodal junction maintenance 1
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