Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:exosomal secretion
go back to main search page
Accession:GO:1990182 term browser browse the term
Definition:The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
Synonyms:exact_synonym: exosomal secretory pathway;   extracellular vesicular exosome secretion;   multi-vesicular body fusion with plasma membrane;   secretion of exosome
 narrow_synonym: exosomal protein secretion
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


show annotations for term's descendants           Sort by:
 
exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:63,586,062...63,605,213
Ensembl chr 8:65,247,950...65,266,511 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,810,880...44,833,438
Ensembl chr15:63,088,084...63,108,077 		JBrowse link
G RAB27A RAB27A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:34,174,491...34,263,045
Ensembl chr15:52,498,202...52,529,984 		JBrowse link
G STEAP3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (MGI:4367682|PMID:18617898) MGI PMID:18617898 MGI:4367682 NCBI chr2B:6,166,296...6,208,338
Ensembl chr2B:119,752,363...119,787,051 		JBrowse link
G TSG101 tumor susceptibility 101 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149 		JBrowse link
negative regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP9A ATPase phospholipid transporting 9A (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:47,944,444...48,116,500
Ensembl chr20:49,067,994...49,204,871 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISO (PMID:26911690) ParkinsonsUK-UCL PMID:26911690 NCBI chr 3:125,784,604...125,873,051 JBrowse link
G VPS4B vacuolar protein sorting 4 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:56,749,439...56,782,660
Ensembl chr18:60,060,285...60,095,109 		JBrowse link
positive regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,929,613...15,955,631
Ensembl chr 1:16,986,385...17,006,033
Ensembl chr 1:16,986,385...17,006,033 		JBrowse link
G CHMP2A charged multivesicular body protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:55,564,622...55,568,214
Ensembl chr19:64,377,986...64,381,417 		JBrowse link
G HGS hepatocyte growth factor-regulated tyrosine kinase substrate involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:76,143,212...76,161,469
Ensembl chr17:81,844,379...81,862,335 		JBrowse link
G MYO5B myosin VB ISO RGD PMID:18984164 RGD:11533643 NCBI chr18:43,207,387...43,575,951
Ensembl chr18:46,555,259...46,786,223 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:33,719,603...33,793,301
Ensembl chr 3:34,016,474...34,093,631 		JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in ISO (PMID:22660413) UniProt PMID:22660413 NCBI chr 3:125,784,604...125,873,051 JBrowse link
G SDC1 syndecan 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:20,187,249...20,211,567
Ensembl chr2A:20,302,589...20,309,848 		JBrowse link
G SDC4 syndecan 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,656,406...41,679,549
Ensembl chr20:42,746,281...42,769,737 		JBrowse link
G SDCBP syndecan binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in ISO PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871 		JBrowse link
G SNF8 SNF8 subunit of ESCRT-II involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,595,647...8,609,730
Ensembl chr17:8,578,050...8,794,480 		JBrowse link
G STAM signal transducing adaptor molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:17,962,759...18,035,654
Ensembl chr10:18,232,548...18,305,197 		JBrowse link
G TSG101 tumor susceptibility 101 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A involved_in ISO (PMID:22660413) UniProt PMID:22660413 NCBI chr16:49,685,827...49,699,542 JBrowse link
G VPS4B vacuolar protein sorting 4 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:56,749,439...56,782,660
Ensembl chr18:60,060,285...60,095,109 		JBrowse link
regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHMP6 charged multivesicular body protein 6 NOT|involved_in ISO (PMID:22660413) UniProt PMID:22660413 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962 		JBrowse link
G LOC100970314 charged multivesicular body protein 3 NOT|involved_in ISO (PMID:22660413) UniProt PMID:22660413 NCBI chr2A:86,559,695...86,619,615
Ensembl chr2A:88,106,242...88,165,104 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15338
    localization 4791
      establishment of localization 4194
        establishment of localization in cell 1908
          establishment of vesicle localization 147
            exosomal secretion 23
              multivesicular body fusion to apical plasma membrane 0
              negative regulation of exosomal secretion 4
              positive regulation of exosomal secretion 15
              regulation of exosomal secretion + 19
Path 2
Term Annotations click to browse term
  biological_process 15338
    localization 4791
      establishment of localization 4194
        transport 4029
          secretion 1042
            secretion by cell 879
              exocytosis 359
                exosomal secretion 23
                  multivesicular body fusion to apical plasma membrane 0
                  negative regulation of exosomal secretion 4
                  positive regulation of exosomal secretion 15
                  regulation of exosomal secretion + 19
paths to the root