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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin synthase complex
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Accession:GO:1990140 term browser browse the term
Definition:A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
Synonyms:exact_synonym: MPT synthase complex;   molybdopterin converting factor complex
 related_synonym: molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex



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molybdopterin synthase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocs2 molybdenum cofactor synthesis 2 part_of ISO
IEA
UniProtKB:O96007|UniProtKB:O96033 (PMID:12732628), (PMID:16021469)
GO_REF:0000107
RGD
Ensembl
PMID:12732628 PMID:16021469 GO_REF:0000107 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324
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Path 1
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      cytosol 4233
        sulfurtransferase complex 7
          molybdopterin synthase complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      intracellular anatomical structure 15184
        cytoplasm 11874
          cytosol 4233
            sulfurtransferase complex 7
              molybdopterin synthase complex 1
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