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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.



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intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor, beta 2 acts_upstream_of IGI (PMID:16571598) MGI PMID:16571598 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor, beta 2 acts_upstream_of_or_within IGI (PMID:16571598) MGI PMID:16571598 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tifab TRAF-interacting protein with forkhead-associated domain, family member B acts_upstream_of_or_within IMP (PMID:32101751) MGI PMID:32101751 NCBI chr13:56,318,917...56,326,816
Ensembl chr13:56,321,517...56,326,698
JBrowse link
G Usp15 ubiquitin specific peptidase 15 acts_upstream_of_or_within IMP (PMID:32101751) MGI PMID:32101751 NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    response to stimulus 10756
      response to abiotic stimulus 1635
        response to osmotic stress 129
          cellular response to osmotic stress 83
            intrinsic apoptotic signaling pathway in response to osmotic stress 11
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 3
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13112
      regulation of biological process 12722
        signaling 7275
          signal transduction 6659
            apoptotic signaling pathway 686
              intrinsic apoptotic signaling pathway 348
                intrinsic apoptotic signaling pathway by p53 class mediator 89
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 3
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
paths to the root