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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to nerve growth factor stimulus
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Accession:GO:1990090 term browser browse the term
Definition:A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
Synonyms:exact_synonym: cellular response to NGF



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cellular response to nerve growth factor stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 involved_in IDA PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr11:69,538,487...69,654,156
Ensembl chr11:69,538,546...69,654,151
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEP
IDA
ISO
PMID:20605787
(PMID:20605787)
RGD PMID:20605787 PMID:9492284 PMID:20605787 RGD:39128201, RGD:10402036 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apc APC regulator of WNT signaling pathway IEP RGD PMID:22399805 RGD:7245986 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G App amyloid beta precursor protein IEP RGD PMID:10821917 RGD:10054256 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arf6 ADP-ribosylation factor 6 involved_in IDA PMID:26446845 UniProt PMID:26446845 RGD:11554955 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IEP RGD PMID:10797548 RGD:11049163 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 IEP RGD PMID:10797548 RGD:11049163 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP RGD PMID:21958434 RGD:8657122 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bptf bromodomain PHD finger transcription factor IEP RGD PMID:11640947 RGD:9586055 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IEP RGD PMID:12138204 RGD:11567269 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Calca calcitonin-related polypeptide alpha acts_upstream_of_or_within IEP
ISO
(MGI:5571523|PMID:24760869) RGD PMID:24760869 PMID:21958434 MGI:5571523, RGD:8657122 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cbl Cbl proto-oncogene IEP RGD PMID:19546888 RGD:11038823 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cdc5l cell division cycle 5-like IDA RGD PMID:20629186 RGD:10045890 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21215777)
UniProt
RGD
PMID:21215777 GO_REF:0000024 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IEP RGD PMID:18193038 RGD:10059421 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IDA RGD PMID:15128873 RGD:1642627 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Csnk1d casein kinase 1, delta IEP RGD PMID:21698236 RGD:10059659 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
JBrowse link
G Csnk1e casein kinase 1, epsilon IEP RGD PMID:21698236 RGD:10059659 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 IEP RGD PMID:23948079 RGD:9686373 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476
JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP RGD PMID:10407183 RGD:9588607 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 IEP RGD PMID:8922673 RGD:13207348 NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 IEP RGD PMID:11536324 RGD:13207410 NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IDA RGD PMID:11536324 RGD:13207410 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 IDA RGD PMID:11536324 RGD:13207410 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G E2f1 E2F transcription factor 1 IDA RGD PMID:18367454 RGD:8693614 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 IEP RGD PMID:11907030 RGD:1304240 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Ehd1 EH-domain containing 1 involved_in IDA PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
JBrowse link
G Elavl4 ELAV like RNA binding protein 4 IEP RGD PMID:12859688 PMID:9514914 RGD:1579855, RGD:9685344 NCBI chr 5:125,056,848...125,200,543
Ensembl chr 5:125,056,848...125,200,446
JBrowse link
G Ep300 E1A binding protein p300 IEP RGD PMID:20399742 RGD:7364749 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,178,529
Ensembl chr 7:113,106,247...113,178,529
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP RGD PMID:9011767 RGD:10402043 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Foxo3 forkhead box O3 IEP RGD PMID:24183892 RGD:9495918 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IMP RGD PMID:9389649 RGD:9685378 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP RGD PMID:10936191 RGD:11354963 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IEP RGD PMID:7623812 RGD:9686118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Kat2a lysine acetyltransferase 2A IEP RGD PMID:15496412 RGD:2312271 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G Kidins220 kinase D-interacting substrate 220 involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 6:41,618,207...41,706,990
Ensembl chr 6:41,618,294...41,703,256
JBrowse link
G Kif1b kinesin family member 1B IEP RGD PMID:24469107 RGD:12738402 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Kif5a kinesin family member 5A IEP RGD PMID:8963445 RGD:12793074 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
JBrowse link
G L1cam L1 cell adhesion molecule IEP RGD PMID:3511068 RGD:11570521 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lcn2 lipocalin 2 IEP RGD PMID:25412834 RGD:126781755 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Micall1 MICAL-like 1 involved_in IDA PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr 7:110,676,706...110,703,028
Ensembl chr 7:110,676,775...110,707,177
JBrowse link
G Myoc myocilin IEP RGD PMID:17663725 RGD:7401258 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Nf1 neurofibromin 1 IEP RGD PMID:8892969 RGD:12789704 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
PMID:17724123
(MGI:5571523|PMID:24760869)
PMID:26446845
PMID:21873635
(PMID:1281417)
RGD PMID:1281417 PMID:24760869 PMID:17724123 PMID:26446845 PMID:21873635 MGI:5571523, RGD:8554481, RGD:11554955, RGD:13792537 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:21958434 PMID:21873635 RGD:8657122, RGD:13792537 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Nts neurotensin IEP RGD PMID:7898306 RGD:9743905 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Optn optineurin IEP RGD PMID:17663725 RGD:7401258 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Pten phosphatase and tensin homolog IEP RGD PMID:10662831 RGD:12801496 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rab35 RAB35, member RAS oncogene family involved_in IDA PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr12:40,967,102...40,981,183
Ensembl chr12:40,967,103...40,991,195
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in IEP
IDA
PMID:17724123 RGD
UniProt
PMID:17822405 PMID:17724123 RGD:10040965, RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:17724123) RGD PMID:17724123 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 IEP RGD PMID:25126967 RGD:9850100 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rpl8 ribosomal protein L8 IEP RGD PMID:11922865 RGD:11039448 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rpl9 ribosomal protein L9 IEP RGD PMID:11922865 RGD:11039448 NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136
JBrowse link
G Rps3 ribosomal protein S3 involved_in IDA PMID:20605787 UniProt PMID:20605787 RGD:10402036 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:21596853 RGD:8547918 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Snx27 sorting nexin 27 IEP RGD PMID:16076023 RGD:13508621 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
G Stmn2 stathmin 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:21215777)
UniProt
RGD
PMID:21215777 GO_REF:0000024 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Tac1 tachykinin, precursor 1 acts_upstream_of_or_within ISO (MGI:5571523|PMID:24760869) RGD PMID:24760869 MGI:5571523 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IEP RGD PMID:21958434 RGD:8657122 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Usp8 ubiquitin specific peptidase 8 IDA RGD PMID:25662281 RGD:11053004 NCBI chr 3:113,962,136...114,009,683
Ensembl chr 3:113,962,164...114,009,666
JBrowse link
cellular response to brain-derived neurotrophic factor stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crnkl1 crooked neck pre-mRNA splicing factor 1 IEP RGD PMID:12801913 RGD:634609 NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 IEP RGD PMID:19625250 RGD:10401254 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase IEP RGD PMID:19625250 RGD:10401254 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IEP RGD PMID:17632064 RGD:10044262 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Irs1 insulin receptor substrate 1 IEP RGD PMID:17467122 RGD:10045898 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IDA RGD PMID:11520908 RGD:10045822 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:21958434 PMID:21873635 RGD:8657122, RGD:13792537 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 IEP RGD PMID:18971483 RGD:10449508 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5825424|PMID:21849472)
UniProt
RGD
PMID:21849472 GO_REF:0000024 MGI:5825424 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843
JBrowse link
G Tmem108 transmembrane protein 108 involved_in ISO (MGI:5825407|PMID:27605705), (MGI:5825424|PMID:21849472) RGD PMID:21849472 PMID:27605705 MGI:5825407 MGI:5825424 NCBI chr 8:104,066,081...104,360,172
Ensembl chr 8:104,066,078...104,360,094
JBrowse link
G Ube3a ubiquitin protein ligase E3A IEP RGD PMID:25867122 RGD:11079590 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250
JBrowse link
G Wasf1 WASP family member 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5825407|PMID:27605705)
UniProt
RGD
PMID:27605705 GO_REF:0000024 MGI:5825407 NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996
JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Coro1a coronin 1A acts_upstream_of_or_within ISO MGI:97321|MGI:97383 (MGI:5559799|PMID:24270184) RGD PMID:24270184 MGI:5559799 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Kidins220 kinase D-interacting substrate 220 involved_in IDA
IBA
PMID:17724123
PMID:21873635
UniProt
GO_Central
PMID:17724123 PMID:21873635 RGD:8554481, RGD:13792537 NCBI chr 6:41,618,207...41,706,990
Ensembl chr 6:41,618,294...41,703,256
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 4:14,388,322...15,870,036
Ensembl chr 4:14,386,399...15,870,240
JBrowse link
G Ngf nerve growth factor involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1345961|MGI:97383 (MGI:5559799|PMID:24270184), (MGI:69378|PMID:7854358)
RGD PMID:7854358 PMID:24270184 PMID:21873635 MGI:5559799 MGI:69378, RGD:13792537 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ntf3 neurotrophin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntf4 neurotrophin 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in
acts_upstream_of_or_within
ISO
IDA
IBA
(PMID:1281417)
MGI:1345961|MGI:97321 (MGI:5559799|PMID:24270184), (MGI:69378|PMID:7854358)
PMID:17724123
PMID:21873635
RGD PMID:1281417 PMID:7854358 PMID:24270184 PMID:17724123 PMID:21873635 MGI:5559799 MGI:69378, RGD:8554481, RGD:13792537 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:17724123) RGD PMID:17724123 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IDA PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Sort1 sortilin 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    response to stimulus 10556
      response to endogenous stimulus 2073
        response to nerve growth factor 84
          cellular response to nerve growth factor stimulus 80
            cellular response to brain-derived neurotrophic factor stimulus 12
            nerve growth factor signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 19834
    response to stimulus 10556
      response to chemical 6262
        response to organic substance 3958
          response to growth factor 832
            cellular response to growth factor stimulus 791
              cellular response to nerve growth factor stimulus 80
                cellular response to brain-derived neurotrophic factor stimulus 12
                nerve growth factor signaling pathway 12
paths to the root