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ONTOLOGY REPORT - ANNOTATIONS


Term:primosome complex
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Accession:GO:1990077 term browser browse the term
Definition:Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.
Synonyms:exact_synonym: primosome


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  cellular_component 20659
    protein-containing complex 6129
      protein-DNA complex 209
        primosome complex 0
          DnaA-DiaA complex 0
          DnaA-HU complex 0
          DnaA-oriC complex 0
          DnaB-DnaC complex 0
          core primosome complex + 0
          pre-primosome complex + 0
Path 2
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  cellular_component 20659
    cellular anatomical entity 20354
      intracellular anatomical structure 14713
        intracellular organelle 12520
          intracellular non-membrane-bounded organelle 5342
            chromosome 1591
              replication fork 69
                replisome 23
                  primosome complex 0
                    DnaA-DiaA complex 0
                    DnaA-HU complex 0
                    DnaA-oriC complex 0
                    DnaB-DnaC complex 0
                    core primosome complex + 0
                    pre-primosome complex + 0
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