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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chromosome separation
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Accession:GO:1905819 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.
Synonyms:exact_synonym: down regulation of chromosome separation;   downregulation of chromosome separation
 narrow_synonym: down regulation of rDNA separation;   downregulation of rDNA separation;   inhibition of chromosome separation;   inhibition of rDNA separation;   negative regulation of rDNA separation
 related_synonym: down regulation of chromatid release;   downregulation of chromatid release;   inhibition of chromatid release;   negative regulation of chromatid release


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) CAFA PMID:22581055 NCBI chrNW_004936641:916,695...925,411 JBrowse link
G LOC101954960 MAD2L1 binding protein involved_in ISO (PMID:18022368) UniProt PMID:18022368 NCBI chrNW_004936476:16,379,932...16,385,812 JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chrNW_004936754:1,842,588...1,957,116 JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chrNW_004936486:19,477,278...19,480,387 JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk TTK protein kinase acts_upstream_of_or_within ISO (MGI:5049806|PMID:21558374) MGI PMID:21558374 MGI:5049806 NCBI chrNW_004936510:10,176,968...10,213,483 JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO (PMID:10935642) UniProt PMID:10935642 NCBI chrNW_004936660:2,725,019...2,754,564 JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:17227893) MGI PMID:17227893 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) UniProt PMID:11943150 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Birc5 baculoviral IAP repeat containing 5 involved_in ISO (PMID:12805209) UniProt PMID:12805209 NCBI chrNW_004936594:2,812,165...2,820,618 JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chrNW_004936520:188,601...265,904 JBrowse link
G Ik IK cytokine involved_in ISO (PMID:22351768) UniProt PMID:22351768 NCBI chrNW_004936531:9,589,035...9,601,266 JBrowse link
G Klhl22 kelch like family member 22 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004936619:2,854,915...2,899,386 JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO (PMID:11146660) UniProt PMID:11146660 NCBI chrNW_004936558:1,936,946...2,016,474 JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:18981471) UniProt PMID:18981471 NCBI chrNW_004936754:1,842,588...1,957,116 JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within
ISO (PMID:18981471)
(MGI:1930685|PMID:11201745)
UniProt
MGI
PMID:11201745 PMID:18981471 MGI:1930685 NCBI chrNW_004936662:92,421...98,531 JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004936501:8,321,415...8,332,414 JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (MGI:2388532|PMID:12147697) MGI PMID:12147697 MGI:2388532 NCBI chrNW_004936626:2,328,646...2,344,831 JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in ISO (MGI:5318128|PMID:22405274) UniProt PMID:22405274 MGI:5318128 NCBI chrNW_004936490:4,499,825...4,576,952 JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:20133940) UniProt PMID:20133940 NCBI chrNW_004936481:4,050,693...4,111,682 JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO (PMID:28553959) UniProt PMID:28553959 NCBI chrNW_004936815:734,029...745,381 JBrowse link
G Ttk TTK protein kinase involved_in ISO (MGI:5608719|PMID:25197064) MGI PMID:25197064 MGI:5608719 NCBI chrNW_004936510:10,176,968...10,213,483 JBrowse link
G Znf207 zinc finger protein 207 involved_in ISO (PMID:24462186), (PMID:24462187) UniProt PMID:24462186 PMID:24462187 NCBI chrNW_004936538:2,514,772...2,541,198 JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISO (PMID:11146660) UniProt PMID:11146660 NCBI chrNW_004936612:825,419...860,971 JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO (PMID:15485811) HGNC-UCL PMID:15485811 NCBI chrNW_004936693:1,539,987...1,551,685 JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISO (PMID:12533425)
(MGI:67285|PMID:8015610), (MGI:67286|PMID:8015609)
AgBase
UniProt
PMID:8015609 PMID:8015610 PMID:12533425 MGI:67285 MGI:67286 NCBI chrNW_004936496:2,763,822...2,764,871 JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:11988738), (PMID:16921029) UniProt PMID:11988738 PMID:16921029 NCBI chrNW_004936489:5,589,621...5,602,221 JBrowse link
G Rad21 RAD21 cohesin complex component involved_in ISO (MGI:1340883|PMID:10375619) CAFA PMID:10375619 MGI:1340883 NCBI chrNW_004936470:29,377,793...29,403,422 JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO (PMID:19229290) UniProt PMID:19229290 NCBI chrNW_004936473:23,011,888...23,042,497 JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chrNW_004936493:13,157,114...13,182,797 JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
(PMID:8824189)
UniProt PMID:8824189 PMID:20870947 MGI:4839685 NCBI chrNW_004936662:92,421...98,531 JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) UniProt PMID:25743205 NCBI chrNW_004936672:1,872,205...1,910,956 JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
UniProt PMID:20870947 MGI:4839685 NCBI chrNW_004936472:440,440...464,116 JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:18981471), (PMID:19273613) UniProt PMID:18981471 PMID:19273613 NCBI chrNW_004936481:4,050,693...4,111,682 JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chrNW_004936621:1,462,441...1,474,937 JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO (PMID:21926987) UniProt PMID:21926987 NCBI chrNW_004936498:1,460,795...1,468,363 JBrowse link
G Ccnb1 cyclin B1 involved_in ISO (PMID:18195732) BHF-UCL PMID:18195732 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISO (PMID:19282672) UniProt PMID:19282672 NCBI chrNW_004936487:8,900,375...9,081,547 JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO (PMID:17724024) MGI PMID:17724024 NCBI chrNW_004936501:9,354,607...9,397,675 JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chrNW_004936507:11,663,069...11,692,174 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12166
    negative regulation of biological process 4664
      negative regulation of cellular process 4281
        negative regulation of chromosome segregation 36
          negative regulation of chromosome separation 35
            negative regulation of meiotic chromosome separation + 3
            negative regulation of mitotic sister chromatid separation + 33
Path 2
Term Annotations click to browse term
  biological_process 12166
    biological regulation 8886
      regulation of biological process 8417
        negative regulation of biological process 4664
          negative regulation of cellular process 4281
            negative regulation of cell cycle 305
              negative regulation of cell cycle process 234
                negative regulation of chromosome separation 35
                  negative regulation of meiotic chromosome separation + 3
                  negative regulation of mitotic sister chromatid separation + 33
paths to the root