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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chromosome separation
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Accession:GO:1905819 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.
Synonyms:exact_synonym: down regulation of chromosome separation;   downregulation of chromosome separation
 narrow_synonym: down regulation of rDNA separation;   downregulation of rDNA separation;   inhibition of chromosome separation;   inhibition of rDNA separation;   negative regulation of rDNA separation
 related_synonym: down regulation of chromatid release;   downregulation of chromatid release;   inhibition of chromatid release;   negative regulation of chromatid release


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:122,568,015...122,573,130
Ensembl chr 8:122,568,015...122,573,554
JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:140,008,689...140,321,608
Ensembl chr 5:140,008,689...140,321,552
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:46,147,385...46,153,551
Ensembl chr17:46,147,387...46,153,553
JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:140,093,396...140,097,203
Ensembl chr 7:140,093,395...140,097,200
JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5049806|PMID:21558374)
GO_Central
MGI
PMID:21558374 PMID:21873635 MGI:5049806 MGI:6201960 NCBI chr 9:83,834,651...83,872,390
Ensembl chr 9:83,834,689...83,872,389
JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:110,135,755...110,171,973
Ensembl chr 5:110,135,842...110,171,972
JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Atm ataxia telangiectasia mutated involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Aurkb aurora kinase B involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:69,045,624...69,051,664
Ensembl chr11:69,045,647...69,051,664
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:131,560,367...131,571,895
Ensembl chr 7:131,560,222...131,571,895
JBrowse link
G Cenpe centromere protein E involved_in IMP (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr 3:135,212,563...135,273,540
Ensembl chr 3:135,212,537...135,273,611
JBrowse link
G Cep192 centrosomal protein 192 acts_upstream_of_or_within ISO (MGI:3773587|PMID:18207742) MGI PMID:18207742 MGI:3773587 NCBI chr18:67,800,054...67,885,170
Ensembl chr18:67,800,107...67,885,170
JBrowse link
G Ik IK cytokine involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:36,744,656...36,757,639
Ensembl chr18:36,744,656...36,757,639
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member acts_upstream_of_or_within IMP (MGI:3844372|PMID:19376971) MGI PMID:19376971 MGI:3844372 NCBI chr 9:73,101,381...73,106,631
Ensembl chr 9:73,101,836...73,104,438
JBrowse link
G Klhl22 kelch-like 22 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr16:17,759,621...17,793,382
Ensembl chr16:17,759,618...17,793,382
JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:123,749,692...123,821,593
Ensembl chr 5:123,749,716...123,821,593
JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 5:140,008,689...140,321,608
Ensembl chr 5:140,008,689...140,321,552
JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 acts_upstream_of_or_within
involved_in
IMP
ISO
ISA
IBA
(MGI:1930685|PMID:11201745)
(MGI:1859722|PMID:10892650)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10892650 PMID:11201745 PMID:21873635 GO_REF:0000096 MGI:1859722 MGI:1930685 MGI:4834177 MGI:6201960 NCBI chr 6:66,535,221...66,541,107
Ensembl chr 6:66,535,390...66,547,220
JBrowse link
G Mad2l1bp MAD2L1 binding protein acts_upstream_of_or_within ISO (MGI:2678840|PMID:14568551), (MGI:2678953|PMID:12456649) MGI PMID:12456649 PMID:14568551 MGI:2678840 MGI:2678953 NCBI chr17:46,147,385...46,153,551
Ensembl chr17:46,147,387...46,153,553
JBrowse link
G Plk1 polo like kinase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:122,159,435...122,169,884
Ensembl chr 7:122,159,439...122,169,873
JBrowse link
G Psmg2 proteasome (prosome, macropain) assembly chaperone 2 acts_upstream_of_or_within IDA (MGI:2388532|PMID:12147697) MGI PMID:12147697 MGI:2388532 NCBI chr18:67,641,587...67,654,181
Ensembl chr18:67,641,599...67,654,162
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:34,809,185...34,833,665
Ensembl chr11:34,809,190...34,833,641
JBrowse link
G Tex14 testis expressed gene 14 involved_in IMP
IBA
(MGI:5318128|PMID:22405274)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:22405274 MGI:5318128 MGI:6201960 NCBI chr11:87,405,013...87,555,823
Ensembl chr11:87,405,065...87,555,823
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:150,392,802...150,449,935
Ensembl chr 1:150,392,838...150,449,935
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:73,912,450...73,937,795
Ensembl chr13:73,911,347...73,937,784
JBrowse link
G Ttk Ttk protein kinase involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5608719|PMID:25197064)
GO_Central
MGI
PMID:21873635 PMID:25197064 MGI:5608719 MGI:6201960 NCBI chr 9:83,834,651...83,872,390
Ensembl chr 9:83,834,689...83,872,389
JBrowse link
G Zfp207 zinc finger protein 207 involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:80,383,279...80,408,561
Ensembl chr11:80,383,279...80,405,733
JBrowse link
G Zw10 zw10 kinetochore protein involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 9:49,055,576...49,078,775
Ensembl chr 9:49,055,613...49,078,775
JBrowse link
G Zwilch zwilch kinetochore protein involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:64,137,144...64,173,104
Ensembl chr 9:64,137,144...64,173,104
JBrowse link
G Zwint ZW10 interactor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:72,654,846...72,674,964
Ensembl chr10:72,654,845...72,674,964
JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos Moloney sarcoma oncogene involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:67285|PMID:8015610), (MGI:67286|PMID:8015609)
GO_Central
UniProt
PMID:8015609 PMID:8015610 PMID:21873635 MGI:6201960 MGI:67285 MGI:67286 NCBI chr 4:3,870,658...3,872,105
Ensembl chr 4:3,870,657...3,872,105
JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:5,799,158...5,805,465
Ensembl chr10:5,799,160...5,805,600
JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 acts_upstream_of_or_within TAS (MGI:2388532|PMID:12147697) MGI PMID:12147697 MGI:2388532 NCBI chr 6:66,535,221...66,541,107
Ensembl chr 6:66,535,390...66,547,220
JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IMP (MGI:1340883|PMID:10375619) CAFA PMID:10375619 MGI:1340883 NCBI chr15:51,962,604...51,993,538
Ensembl chr15:51,962,240...51,991,747
JBrowse link
negative regulation of mitotic sister chromatid separation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pttg1 pituitary tumor-transforming gene 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:43,420,244...43,427,463
Ensembl chr11:43,420,250...43,426,251
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:114,688,831...114,723,788
Ensembl chr 9:114,688,790...114,724,302
JBrowse link
G Gen1 GEN1, Holliday junction 5' flap endonuclease involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:11,238,928...11,266,029
Ensembl chr12:11,238,920...11,265,801
JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 involved_in IMP
ISO
(MGI:4839685|PMID:20870947) UniProt
MGI
PMID:20870947 GO_REF:0000096 MGI:4834177 MGI:4839685 NCBI chr 6:66,535,221...66,541,107
Ensembl chr 6:66,535,390...66,547,220
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:71,496,100...71,526,857
Ensembl chr17:71,496,100...71,526,857
JBrowse link
G Pcid2 PCI domain containing 2 involved_in IMP
ISO
(MGI:4839685|PMID:20870947) UniProt
MGI
PMID:20870947 GO_REF:0000096 MGI:4834177 MGI:4839685 NCBI chr 8:13,075,476...13,105,343
Ensembl chr 8:13,077,189...13,105,459
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:150,392,802...150,449,935
Ensembl chr 1:150,392,838...150,449,935
JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr12:111,803,192...111,813,893
Ensembl chr12:111,803,192...111,813,873
JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex C subunit 15 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:101,881,300...101,901,849
Ensembl chr 7:101,863,715...101,901,849
JBrowse link
G Ccnb1 cyclin B1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:70,216,855...70,410,435
Ensembl chr 4:70,216,856...70,410,443
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO MGI GO_REF:0000008 MGI:2154458 NCBI chr 7:123,377,803...123,430,358
Ensembl chr 7:123,369,784...123,430,358
JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in IDA (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chr10:93,819,969...93,859,425
Ensembl chr10:93,831,555...93,858,088
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28599
    negative regulation of biological process 5755
      negative regulation of cellular process 5206
        negative regulation of chromosome segregation 45
          negative regulation of chromosome separation 44
            negative regulation of meiotic chromosome separation + 3
            negative regulation of mitotic sister chromatid separation + 42
Path 2
Term Annotations click to browse term
  biological_process 28599
    biological regulation 13250
      regulation of biological process 12597
        negative regulation of biological process 5755
          negative regulation of cellular process 5206
            negative regulation of cell cycle 370
              negative regulation of cell cycle process 285
                negative regulation of chromosome separation 44
                  negative regulation of meiotic chromosome separation + 3
                  negative regulation of mitotic sister chromatid separation + 42
paths to the root