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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chromosome separation
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Accession:GO:1905819 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.
Synonyms:exact_synonym: down regulation of chromosome separation;   downregulation of chromosome separation
 narrow_synonym: down regulation of rDNA separation;   downregulation of rDNA separation;   inhibition of chromosome separation;   inhibition of rDNA separation;   negative regulation of rDNA separation
 related_synonym: down regulation of chromatid release;   downregulation of chromatid release;   inhibition of chromatid release;   negative regulation of chromatid release


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDT1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) CAFA PMID:22581055 NCBI chr 5:64,566,035...64,570,361
Ensembl chr 5:64,566,043...64,570,748
JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192
JBrowse link
G MAD2L1BP MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:12,085,825...12,089,907
Ensembl chr12:12,085,915...12,090,411
JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chr28:40,927,744...40,931,355 JBrowse link
meiotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TTK TTK protein kinase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5049806|PMID:21558374)
GO_Central
MGI
PMID:21558374 PMID:21873635 MGI:5049806 NCBI chr12:40,915,733...40,959,423
Ensembl chr12:40,915,439...40,957,279
JBrowse link
meiotic spindle checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHFR checkpoint with forkhead and ring finger domains involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:251,369...324,699
Ensembl chr26:294,909...324,696
JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:17227893) MGI PMID:17227893 NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISO (PMID:11943150) UniProt PMID:11943150 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G AURKB aurora kinase B involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:33,014,098...33,028,951
Ensembl chr 5:33,014,102...33,033,948
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IEA InterPro GO_REF:0000002 NCBI chr17:35,208,989...35,252,296
Ensembl chr17:35,208,991...35,252,975
JBrowse link
G CENPE centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chr32:24,447,373...24,530,407
Ensembl chr32:24,447,358...24,530,382
JBrowse link
G IK IK cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,805,631...35,818,205
Ensembl chr 2:35,805,689...35,818,050
JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member acts_upstream_of_or_within ISO (MGI:3844372|PMID:19376971) MGI PMID:19376971 MGI:3844372 NCBI chr12:35,434,123...35,435,679
Ensembl chr12:35,434,123...35,468,943
JBrowse link
G KLHL22 kelch like family member 22 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chr26:30,248,253...30,281,989
Ensembl chr26:30,248,240...30,281,843
JBrowse link
G KNTC1 kinetochore associated 1 involved_in ISO (PMID:11146660) UniProt PMID:11146660 NCBI chr26:6,777,667...6,867,798
Ensembl chr26:6,777,383...6,865,016
JBrowse link
G LOC100687713 BUB3-interacting and GLEBS motif-containing protein ZNF207 involved_in ISO (PMID:24462186), (PMID:24462187) UniProt PMID:24462186 PMID:24462187 NCBI chr11:1,027,387...1,029,505 JBrowse link
G LOC476070 mitotic arrest deficient 2 like 1 involved_in
acts_upstream_of_or_within
ISO (PMID:18981471)
(MGI:1930685|PMID:11201745)
UniProt
MGI
PMID:11201745 PMID:18981471 MGI:1930685 NCBI chr18:55,653,677...55,661,017 JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:14,889,126...15,236,194
Ensembl chr 6:14,882,875...15,236,192
JBrowse link
G PLK1 polo like kinase 1 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chr 6:22,165,338...22,176,847
Ensembl chr 6:22,165,338...22,176,441
JBrowse link
G PSMG2 proteasome assembly chaperone 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2388532|PMID:12147697) Ensembl
MGI
PMID:12147697 GO_REF:0000107 MGI:2388532 NCBI chr 7:78,092,877...78,112,831
Ensembl chr 7:78,092,876...78,112,702
JBrowse link
G TEX14 testis expressed 14, intercellular bridge forming factor involved_in ISO (MGI:5318128|PMID:22405274) UniProt PMID:22405274 MGI:5318128 NCBI chr 9:33,174,813...33,289,202
Ensembl chr 9:33,174,814...33,262,870
JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in ISO (PMID:20133940) UniProt PMID:20133940 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:11,522,940...11,539,885
Ensembl chr34:11,522,940...11,539,885
JBrowse link
G TTK TTK protein kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:40,915,733...40,959,423
Ensembl chr12:40,915,439...40,957,279
JBrowse link
G ZW10 zw10 kinetochore protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:19,496,531...19,527,205
Ensembl chr 5:19,496,611...19,527,200
JBrowse link
G ZWINT ZW10 interacting kinetochore protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:32,432,385...32,459,377
Ensembl chr26:32,432,406...32,453,162
JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MOS MOS proto-oncogene, serine/threonine kinase involved_in ISO (PMID:12533425)
(MGI:67285|PMID:8015610), (MGI:67286|PMID:8015609)
AgBase
UniProt
PMID:8015609 PMID:8015610 PMID:12533425 MGI:67285 MGI:67286 NCBI chr29:7,510,987...7,513,180 JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO5 F-box protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,138,338...43,149,546
Ensembl chr 1:43,138,889...43,149,297
JBrowse link
G RAD21 RAD21 cohesin complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:16,337,563...16,368,041
Ensembl chr13:16,338,972...16,368,035
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO (PMID:19229290) UniProt PMID:19229290 NCBI chr23:12,235,539...12,283,851
Ensembl chr23:12,235,104...12,277,031
JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,201,540...13,233,028
Ensembl chr17:13,201,777...13,232,120
JBrowse link
G LOC476070 mitotic arrest deficient 2 like 1 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)
(PMID:8824189)
UniProt PMID:8824189 PMID:20870947 MGI:4839685 NCBI chr18:55,653,677...55,661,017 JBrowse link
G NDC80 NDC80 kinetochore complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,268,218...69,317,126
Ensembl chr 7:69,268,242...69,317,072
JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719
JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in ISO (PMID:18981471), (PMID:19273613) UniProt PMID:18981471 PMID:19273613 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,441,732...71,452,922
Ensembl chr 8:71,442,429...71,449,408
JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANAPC15 anaphase promoting complex subunit 15 involved_in ISO (PMID:21926987) UniProt PMID:21926987 NCBI chr21:25,971,680...25,975,556
Ensembl chr21:25,972,458...25,975,558
JBrowse link
G CCNB1 cyclin B1 involved_in ISO (PMID:18195732) BHF-UCL PMID:18195732 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 involved_in ISO (PMID:19282672) UniProt PMID:19282672 NCBI chr11:73,548,003...73,693,044
Ensembl chr11:73,548,038...73,690,199
JBrowse link
G LCMT1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17724024) MGI
Ensembl
PMID:17724024 GO_REF:0000107 NCBI chr 6:21,026,125...21,066,884
Ensembl chr 6:21,026,186...21,066,876
JBrowse link
G USP44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:35,401,486...35,454,351
Ensembl chr15:35,402,207...35,414,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13872
    negative regulation of biological process 5056
      negative regulation of cellular process 4591
        negative regulation of chromosome segregation 39
          negative regulation of chromosome separation 38
            negative regulation of meiotic chromosome separation + 3
            negative regulation of mitotic sister chromatid separation + 36
Path 2
Term Annotations click to browse term
  biological_process 13872
    biological regulation 10017
      regulation of biological process 9456
        negative regulation of biological process 5056
          negative regulation of cellular process 4591
            negative regulation of cell cycle 332
              negative regulation of cell cycle process 255
                negative regulation of chromosome separation 38
                  negative regulation of meiotic chromosome separation + 3
                  negative regulation of mitotic sister chromatid separation + 36
paths to the root