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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of blood-brain barrier permeability
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Accession:GO:1905605 term browser browse the term
Definition:Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: positive regulation of BBB permeability;   up-regulation of BBB permeability;   up-regulation of blood-brain barrier permeability;   upregulation of BBB permeability;   upregulation of blood-brain barrier permeability
 narrow_synonym: activation of maintenance of permeability of BBB;   activation of maintenance of permeability of blood-brain barrier



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positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19148554)
Ensembl
RGD
PMID:19148554 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Ocln occludin involved_in ISO (PMID:24854121) RGD PMID:24854121 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO
IBA
(PMID:24854121)
GO_REF:0000033
RGD
GO_Central
PMID:24854121 GO_REF:0000033 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tjp2 tight junction protein 2 involved_in ISO
IBA
(PMID:19148554)
GO_REF:0000033
RGD
GO_Central
PMID:19148554 GO_REF:0000033 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological quality 3367
        regulation of vascular permeability 53
          regulation of blood-brain barrier permeability 10
            positive regulation of blood-brain barrier permeability 5
Path 2
Term Annotations click to browse term
  biological_process 19692
    homeostatic process 1948
      multicellular organismal-level homeostasis 938
        anatomical structure homeostasis 284
          tissue homeostasis 283
            maintenance of blood-brain barrier 24
              regulation of blood-brain barrier permeability 10
                positive regulation of blood-brain barrier permeability 5
paths to the root