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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood-brain barrier permeability
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Accession:GO:1905604 term browser browse the term
Definition:Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: down-regulation of BBB permeability;   down-regulation of blood-brain barrier permeability;   downregulation of BBB permeability;   downregulation of blood-brain barrier permeability;   negative regulation of BBB permeability
 narrow_synonym: inhibition of maintenance of permeability of BBB;   inhibition of maintenance of permeability of blood-brain barrier



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negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:18854840 RGD:2325137 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Ifnb1 interferon beta 1 IDA RGD PMID:12973019 PMID:12973022 RGD:401851924, RGD:401851925 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO
IEA
(PMID:24854121)
GO_REF:0000107
RGD
Ensembl
PMID:24854121 GO_REF:0000107 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA
(PMID:19148554)
GO_REF:0000107
RGD
Ensembl
PMID:19148554 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    biological regulation 13396
      regulation of biological quality 3375
        regulation of vascular permeability 53
          regulation of blood-brain barrier permeability 10
            negative regulation of blood-brain barrier permeability 4
Path 2
Term Annotations click to browse term
  biological_process 19872
    homeostatic process 1962
      multicellular organismal-level homeostasis 947
        anatomical structure homeostasis 287
          tissue homeostasis 287
            maintenance of blood-brain barrier 24
              regulation of blood-brain barrier permeability 10
                negative regulation of blood-brain barrier permeability 4
paths to the root