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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of blood-brain barrier permeability
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Accession:GO:1905603 term browser browse the term
Definition:Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: regulation of BBB permeability
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa

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regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chrNW_004936469:32,240,730...32,372,413
Ensembl chrNW_004936469:32,240,835...32,371,267 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18854840 RGD:2325137 NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:37,105,469...37,328,183
Ensembl chrNW_004936470:37,105,466...37,328,190 		JBrowse link
G Ocln occludin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:99,516...152,834
Ensembl chrNW_004936480:98,371...152,413 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chrNW_004936483:1,814,870...2,045,802
Ensembl chrNW_004936483:1,814,894...2,030,946 		JBrowse link
G Tjp2 tight junction protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:5,414,330...5,539,895
Ensembl chrNW_004936503:5,497,832...5,539,090 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15036
    biological regulation 10560
      regulation of biological quality 2800
        regulation of vascular permeability 45
          regulation of blood-brain barrier permeability 7
            negative regulation of blood-brain barrier permeability 2
            positive regulation of blood-brain barrier permeability 4
Path 2
Term Annotations click to browse term
  biological_process 15036
    homeostatic process 1686
      multicellular organismal-level homeostasis 827
        anatomical structure homeostasis 274
          tissue homeostasis 274
            maintenance of blood-brain barrier 19
              regulation of blood-brain barrier permeability 7
                negative regulation of blood-brain barrier permeability 2
                positive regulation of blood-brain barrier permeability 4
paths to the root