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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of blood-brain barrier permeability
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Accession:GO:1905603 term browser browse the term
Definition:Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: regulation of BBB permeability
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZEB2 zinc finger E-box binding homeobox 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:34334113 GO_REF:0000107 RGD:155882538 NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18854840 GO_REF:0000107 RGD:2325137 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G IFNB1 interferon beta 1 ISO RGD PMID:12973019 PMID:12973022 RGD:401851924 RGD:401851925 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in IMP (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chr 9:17,579,066...17,797,124
Ensembl chr 9:17,579,066...17,797,124 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IMP (PMID:19148554) ARUK-UCL PMID:19148554 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in IMP (PMID:19148554) ARUK-UCL PMID:19148554 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G OCLN occludin involved_in IMP (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G TJP1 tight junction protein 1 involved_in IMP
IBA
IEA		 (PMID:24854121) ARUK-UCL
GO_Central
TreeGrafter		 PMID:24854121 GO_REF:0000033 GO_REF:0000118 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TJP2 tight junction protein 2 involved_in IMP
IEA
IBA		 (PMID:19148554) ARUK-UCL
TreeGrafter
GO_Central		 PMID:19148554 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615 		JBrowse link
G TJP3 tight junction protein 3 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr19:3,708,384...3,750,813
Ensembl chr19:3,708,362...3,750,813 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of biological quality 3535
        regulation of vascular permeability 59
          regulation of blood-brain barrier permeability 10
            negative regulation of blood-brain barrier permeability 4
            positive regulation of blood-brain barrier permeability 5
Path 2
Term Annotations click to browse term
  biological_process 19669
    homeostatic process 2069
      multicellular organismal-level homeostasis 998
        anatomical structure homeostasis 316
          tissue homeostasis 315
            maintenance of blood-brain barrier 43
              regulation of blood-brain barrier permeability 10
                negative regulation of blood-brain barrier permeability 4
                positive regulation of blood-brain barrier permeability 5
paths to the root