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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of blood-brain barrier permeability
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Accession:GO:1905603 term browser browse the term
Definition:Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: regulation of BBB permeability
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa

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regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chrNW_004955440:10,755,658...10,881,044
Ensembl chrNW_004955440:10,756,014...10,795,491 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18854840 RGD:2325137 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chrNW_004955434:20,332,727...20,381,320
Ensembl chrNW_004955434:20,331,779...20,381,376 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:19148554) ARUK-UCL PMID:19148554 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO (PMID:19148554) ARUK-UCL PMID:19148554 NCBI chrNW_004955417:30,199,508...30,386,695
Ensembl chrNW_004955417:30,198,842...30,386,266 		JBrowse link
G Ocln occludin involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chrNW_004955575:163,646...210,379 JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chrNW_004955416:28,640,807...28,869,717
Ensembl chrNW_004955416:28,654,905...28,870,555 		JBrowse link
G Tjp2 tight junction protein 2 involved_in ISO (PMID:19148554) ARUK-UCL PMID:19148554 NCBI chrNW_004955434:3,781,368...3,923,240
Ensembl chrNW_004955434:3,781,113...3,923,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12249
    biological regulation 8868
      regulation of biological quality 2560
        regulation of vascular permeability 41
          regulation of blood-brain barrier permeability 8
            negative regulation of blood-brain barrier permeability 3
            positive regulation of blood-brain barrier permeability 4
Path 2
Term Annotations click to browse term
  biological_process 12249
    homeostatic process 1507
      multicellular organismal-level homeostasis 769
        anatomical structure homeostasis 266
          tissue homeostasis 266
            maintenance of blood-brain barrier 20
              regulation of blood-brain barrier permeability 8
                negative regulation of blood-brain barrier permeability 3
                positive regulation of blood-brain barrier permeability 4
paths to the root