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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of blood-brain barrier permeability
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Accession:GO:1905603 term browser browse the term
Definition:Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: regulation of BBB permeability
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


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regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZEB2 zinc finger E-box binding homeobox 2 ISO RGD PMID:34334113 RGD:155882538 NCBI chr2B:15,325,094...15,460,908
Ensembl chr2B:148,460,904...148,596,500 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18854840 RGD:2325137 NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870 		JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:17,386,298...17,605,722
Ensembl chr 9:18,045,198...18,097,579 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783 		JBrowse link
G OCLN occludin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342 		JBrowse link
G TJP1 tight junction protein 1 involved_in ISO (PMID:24854121) ARUK-UCL PMID:24854121 NCBI chr15:981,198...1,249,292
Ensembl chr15:26,344,878...26,598,878 		JBrowse link
G TJP2 tight junction protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,536,627...55,690,472
Ensembl chr 9:67,886,421...68,021,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15372
    biological regulation 10777
      regulation of biological quality 2876
        regulation of vascular permeability 47
          regulation of blood-brain barrier permeability 8
            negative regulation of blood-brain barrier permeability 3
            positive regulation of blood-brain barrier permeability 4
Path 2
Term Annotations click to browse term
  biological_process 15372
    homeostatic process 1724
      multicellular organismal-level homeostasis 851
        anatomical structure homeostasis 283
          tissue homeostasis 283
            maintenance of blood-brain barrier 20
              regulation of blood-brain barrier permeability 8
                negative regulation of blood-brain barrier permeability 3
                positive regulation of blood-brain barrier permeability 4
paths to the root