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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of blood-brain barrier permeability
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Accession:GO:1905603 term browser browse the term
Definition:Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.
Synonyms:exact_synonym: regulation of BBB permeability
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 IMP RGD PMID:34334113 RGD:155882538 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
negative regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:18854840 RGD:2325137 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 involved_in ISO (PMID:24854121) RGD PMID:24854121 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:19148554)
GO_REF:0000107		 RGD
Ensembl		 PMID:19148554 GO_REF:0000107 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
positive regulation of blood-brain barrier permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19148554)		 Ensembl
RGD		 PMID:19148554 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ocln occludin involved_in ISO (PMID:24854121) RGD PMID:24854121 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Tjp1 tight junction protein 1 involved_in IBA
ISO		 PMID:21873635
(PMID:24854121)		 RGD PMID:24854121 PMID:21873635 RGD:13792537 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 involved_in IBA
ISO		 PMID:21873635
(PMID:19148554)		 RGD PMID:19148554 PMID:21873635 RGD:13792537 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tjp3 tight junction protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    biological regulation 13447
      regulation of biological quality 3327
        regulation of vascular permeability 52
          regulation of blood-brain barrier permeability 9
            negative regulation of blood-brain barrier permeability 3
            positive regulation of blood-brain barrier permeability 5
Path 2
Term Annotations click to browse term
  biological_process 19746
    homeostatic process 1916
      multicellular organismal-level homeostasis 910
        anatomical structure homeostasis 293
          tissue homeostasis 293
            maintenance of blood-brain barrier 22
              regulation of blood-brain barrier permeability 9
                negative regulation of blood-brain barrier permeability 3
                positive regulation of blood-brain barrier permeability 5
paths to the root