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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of low-density lipoprotein receptor activity
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Accession:GO:1905598 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.
Synonyms:exact_synonym: down regulation of LDL receptor;   down regulation of LDLR activity;   down regulation of low-density lipoprotein receptor activity;   downregulation of LDL receptor;   downregulation of LDLR activity;   downregulation of low-density lipoprotein receptor activity;   negative regulation of LDL receptor;   negative regulation of LDLR activity
 narrow_synonym: inhibition of LDL receptor;   inhibition of LDLR activity;   inhibition of low-density lipoprotein receptor activity


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negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 acts_upstream_of
acts_upstream_of_or_within
ISO
IDA
(MGI:5306885|PMID:21810484) MGI
ARUK-UCL
PMID:21810484 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:5306885 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G App amyloid beta (A4) precursor protein NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Itgav integrin alpha V acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:83,722,303...83,806,917
Ensembl chr 2:83,724,397...83,806,916
JBrowse link
G Itgb3 integrin beta 3 acts_upstream_of_or_within ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:106,442,334...106,464,325
Ensembl chr 4:106,442,329...106,464,329
JBrowse link
G Psen1 presenilin 1 NOT|involved_in ISO (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr12:83,688,152...83,735,095
Ensembl chr12:83,688,152...83,735,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23319
    biological regulation 13152
      regulation of molecular function 2724
        negative regulation of molecular function 1098
          negative regulation of low-density lipoprotein receptor activity 7
Path 2
Term Annotations click to browse term
  biological_process 23319
    localization 6261
      establishment of localization 4686
        transport 4526
          regulation of transport 1969
            regulation of vesicle-mediated transport 624
              regulation of endocytosis 242
                negative regulation of endocytosis 50
                  negative regulation of receptor-mediated endocytosis 31
                    negative regulation of low-density lipoprotein receptor activity 7
paths to the root