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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of low-density lipoprotein receptor activity
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Accession:GO:1905598 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.
Synonyms:exact_synonym: down regulation of LDL receptor;   down regulation of LDLR activity;   down regulation of low-density lipoprotein receptor activity;   downregulation of LDL receptor;   downregulation of LDLR activity;   downregulation of low-density lipoprotein receptor activity;   negative regulation of LDL receptor;   negative regulation of LDLR activity
 narrow_synonym: inhibition of LDL receptor;   inhibition of LDLR activity;   inhibition of low-density lipoprotein receptor activity


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negative regulation of low-density lipoprotein receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing acts_upstream_of IDA (PMID:11222466) BHF-UCL PMID:11222466 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G APP amyloid beta precursor protein NOT|involved_in IGI (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ITGAV integrin subunit alpha V acts_upstream_of_or_within IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,056...186,680,901
JBrowse link
G ITGB3 integrin subunit beta 3 acts_upstream_of_or_within IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
G PSEN1 presenilin 1 NOT|involved_in IGI (PMID:20005821) ARUK-UCL PMID:20005821 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18680
    biological regulation 13383
      regulation of molecular function 3385
        negative regulation of molecular function 1269
          negative regulation of low-density lipoprotein receptor activity 7
Path 2
Term Annotations click to browse term
  biological_process 18680
    localization 7254
      establishment of localization 5649
        transport 5497
          regulation of transport 2059
            regulation of vesicle-mediated transport 643
              regulation of endocytosis 254
                negative regulation of endocytosis 54
                  negative regulation of receptor-mediated endocytosis 33
                    negative regulation of low-density lipoprotein receptor activity 7
paths to the root