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ONTOLOGY REPORT - ANNOTATIONS


Term:exoribonuclease complex
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Accession:GO:1905354 term browser browse the term
Definition:A protein complex which is capable of exoribonuclease activity.
Comment:An example of this is DIS3 in human (Q9Y2L1) in PMID:17174896 (inferred from direct assay).


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cytoplasmic exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carhsp1 calcium regulated heat stable protein 1 colocalizes_with ISO
ISS
(MGI:MGI:5320273|PMID:21078874)
GO_REF:0000024
RGD
UniProt
PMID:21078874 GO_REF:0000024, MGI:MGI:5320273 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:83,466,330...83,494,107
Ensembl chr15:83,466,428...83,494,423
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20531386), (PMID:20531389)
UniProt
RGD
PMID:20531386, PMID:20531389, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:69,771,211...69,807,880
Ensembl chr 8:69,771,197...69,807,826
JBrowse link
G Exosc2 exosome component 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G Exosc3 exosome component 3 ISO
IBA
(PMID:11110791)
PMID:21873635
RGD PMID:11110791, PMID:21873635 RGD:13792537 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc4 exosome component 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Exosc5 exosome component 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Exosc6 exosome component 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Exosc7 exosome component 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Exosc8 exosome component 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Exosc9 exosome component 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G Gtpbp1 GTP binding protein 1 IDA PMID:21515746 UniProt PMID:21515746 RGD:8553842 NCBI chr 7:120,923,274...120,947,723
Ensembl chr 7:120,923,274...120,947,723
JBrowse link
exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1d C1D nuclear receptor corepressor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:100,415,645...100,427,878
Ensembl chr14:100,415,668...100,427,260
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:83,466,330...83,494,107
Ensembl chr15:83,466,428...83,494,423
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:69,771,211...69,807,880
Ensembl chr 8:69,771,197...69,807,826
JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:93,767,837...94,161,106
Ensembl chr 9:93,660,680...94,160,760
JBrowse link
G Exosc1 exosome component 1 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 1:261,169,798...261,179,865
Ensembl chr 1:261,170,229...261,179,790
JBrowse link
G Exosc10 exosome component 10 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 5:165,374,964...165,398,195
Ensembl chr 5:165,374,951...165,398,217
JBrowse link
G Exosc2 exosome component 2 IBA
ISO
PMID:21873635
(PMID:12419256), (PMID:20531389)
RGD PMID:12419256, PMID:20531389, PMID:21873635 RGD:13792537 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G Exosc3 exosome component 3 ISO
IBA
(PMID:20531389)
PMID:21873635
RGD PMID:20531389, PMID:21873635 RGD:13792537 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc4 exosome component 4 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Exosc5 exosome component 5 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Exosc6 exosome component 6 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Exosc7 exosome component 7 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Exosc8 exosome component 8 ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Exosc9 exosome component 9 IEA
ISS
ISO
GO_REF:0000002
GO_REF:0000024
(PMID:20531389)
InterPro
UniProt
RGD
PMID:20531389 GO_REF:0000002, GO_REF:0000024 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G Mphosph6 M phase phosphoprotein 6 colocalizes_with ISO (PMID:20531389)
(PMID:11719186)
RGD PMID:11719186, PMID:20531389 NCBI chr19:50,357,314...50,367,137
Ensembl chr19:50,357,338...50,367,187
JBrowse link
G Mtrex Mtr4 exosome RNA helicase colocalizes_with ISO (PMID:11719186) RGD PMID:11719186 NCBI chr 2:44,726,716...44,787,013
Ensembl chr 2:44,717,781...44,786,963
JBrowse link
G Zfc3h1 zinc finger, C3H1-type containing ISO
IBA
(PMID:27871484)
PMID:21873635
RGD PMID:27871484, PMID:21873635 RGD:13792537 NCBI chr 7:58,365,979...58,424,326
Ensembl chr 7:58,366,192...58,423,581
JBrowse link
G Zfp36 zinc finger protein 36 NOT|colocalizes_with ISO
ISS
(PMID:11719186)
GO_REF:0000024
RGD
UniProt
PMID:11719186 GO_REF:0000024 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
Las1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Las1l LAS1-like, ribosome biogenesis factor IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:65,081,591...65,102,344
Ensembl chr  X:65,081,591...65,102,380
JBrowse link
mitochondrial degradosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 ISO (PMID:19509288), (PMID:29967381) RGD PMID:19509288, PMID:29967381 NCBI chr14:113,530,470...113,561,645
Ensembl chr14:113,530,470...113,561,645
JBrowse link
G Supv3l1 Suv3 like RNA helicase IEA
ISO
ISS
IBA
GO_REF:0000107
(PMID:19509288), (PMID:29967381)
GO_REF:0000024
PMID:21873635
Ensembl
RGD
UniProt
PMID:19509288, PMID:29967381, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr20:32,057,530...32,080,170
Ensembl chr20:32,057,454...32,080,088
JBrowse link
nuclear exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease ISO
IBA
(PMID:20531386)
PMID:21873635
RGD PMID:20531386, PMID:21873635 RGD:13792537 NCBI chr15:83,466,330...83,494,107
Ensembl chr15:83,466,428...83,494,423
JBrowse link
G Exosc1 exosome component 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:261,169,798...261,179,865
Ensembl chr 1:261,170,229...261,179,790
JBrowse link
G Exosc10 exosome component 10 ISO
IBA
(PMID:26166824)
PMID:21873635
RGD PMID:26166824, PMID:21873635 RGD:13792537 NCBI chr 5:165,374,964...165,398,195
Ensembl chr 5:165,374,951...165,398,217
JBrowse link
G Exosc2 exosome component 2 ISO
IBA
(PMID:26166824)
PMID:21873635
RGD PMID:26166824, PMID:21873635 RGD:13792537 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G Exosc3 exosome component 3 ISO
IBA
(PMID:11110791)
PMID:21873635
RGD PMID:11110791, PMID:21873635 RGD:13792537 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc4 exosome component 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G Exosc5 exosome component 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Exosc6 exosome component 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Exosc7 exosome component 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Exosc8 exosome component 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Exosc9 exosome component 9 ISO
IBA
(PMID:22791713)
PMID:21873635
RGD PMID:22791713, PMID:21873635 RGD:13792537 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G Mphosph6 M phase phosphoprotein 6 colocalizes_with ISO (PMID:26166824) RGD PMID:26166824 NCBI chr19:50,357,314...50,367,137
Ensembl chr19:50,357,338...50,367,187
JBrowse link
G Mtrex Mtr4 exosome RNA helicase colocalizes_with ISO (PMID:26166824) RGD PMID:26166824 NCBI chr 2:44,726,716...44,787,013
Ensembl chr 2:44,717,781...44,786,963
JBrowse link
G Nvl nuclear VCP-like colocalizes_with ISO (PMID:26166824) RGD PMID:26166824 NCBI chr13:99,410,026...99,468,783
Ensembl chr13:99,410,026...99,468,778
JBrowse link
G Wdr74 WD repeat domain 74 colocalizes_with ISO (PMID:26456651) RGD PMID:26456651 NCBI chr 1:224,933,906...224,938,659
Ensembl chr 1:224,933,529...224,938,662
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20609
    protein-containing complex 6092
      catalytic complex 1487
        exoribonuclease complex 25
          Las1 complex 1
          RNA polymerase II termination complex 0
          exosome (RNase complex) + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.