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ONTOLOGY REPORT - ANNOTATIONS


Term:exoribonuclease complex
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Accession:GO:1905354 term browser browse the term
Definition:A protein complex which is capable of exoribonuclease activity.
Comment:An example of this is DIS3 in human (Q9Y2L1) in PMID:17174896 (inferred from direct assay).


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cytoplasmic exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carhsp1 calcium regulated heat stable protein 1 colocalizes_with
part_of
ISS
ISO
GO_REF:0000024
(MGI:5320273|PMID:21078874)
UniProt
RGD
PMID:21078874 GO_REF:0000024 MGI:5320273 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease part_of IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20531386), (PMID:20531389)
UniProt
RGD
PMID:20531386 PMID:20531389 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165
JBrowse link
G Exosc2 exosome component 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
JBrowse link
G Exosc3 exosome component 3 part_of ISO
IBA
(PMID:11110791)
PMID:21873635
RGD PMID:11110791 PMID:21873635 RGD:13792537 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc4 exosome component 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
JBrowse link
G Exosc5 exosome component 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Exosc6 exosome component 6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Exosc7 exosome component 7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Exosc8 exosome component 8 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exosc9 exosome component 9 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Gtpbp1 GTP binding protein 1 part_of IDA PMID:21515746 UniProt PMID:21515746 RGD:8553842 NCBI chr 7:111,248,254...111,272,705
Ensembl chr 7:111,248,254...111,272,705
JBrowse link
exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1d C1D nuclear receptor corepressor part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165
JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
JBrowse link
G Exosc1 exosome component 1 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 1:240,734,777...240,745,518
Ensembl chr 1:240,734,773...240,745,438
JBrowse link
G Exosc10 exosome component 10 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Exosc2 exosome component 2 part_of IBA
ISO
PMID:21873635
(PMID:12419256), (PMID:20531389)
RGD PMID:12419256 PMID:20531389 PMID:21873635 RGD:13792537 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
JBrowse link
G Exosc3 exosome component 3 part_of IBA
ISO
PMID:21873635
(PMID:20531389)
RGD PMID:20531389 PMID:21873635 RGD:13792537 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc4 exosome component 4 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
JBrowse link
G Exosc5 exosome component 5 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Exosc6 exosome component 6 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Exosc7 exosome component 7 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Exosc8 exosome component 8 part_of ISO (PMID:20531389) RGD PMID:20531389 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exosc9 exosome component 9 part_of ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000002
(PMID:20531389)
UniProt
InterPro
RGD
PMID:20531389 GO_REF:0000002 GO_REF:0000024 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Mphosph6 M phase phosphoprotein 6 colocalizes_with
part_of
ISO (PMID:11719186)
(PMID:20531389)
RGD PMID:11719186 PMID:20531389 NCBI chr19:45,860,152...45,870,077
Ensembl chr19:45,860,154...45,870,170
JBrowse link
G Mtrex Mtr4 exosome RNA helicase colocalizes_with ISO (PMID:11719186) RGD PMID:11719186 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Zfc3h1 zinc finger, C3H1-type containing part_of ISO
IBA
(PMID:27871484)
PMID:21873635
RGD PMID:27871484 PMID:21873635 RGD:13792537 NCBI chr 7:51,008,251...51,064,666
Ensembl chr 7:51,007,984...51,064,661
JBrowse link
G Zfp36 zinc finger protein 36 NOT|colocalizes_with ISO
ISS
(PMID:11719186)
GO_REF:0000024
RGD
UniProt
PMID:11719186 GO_REF:0000024 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
Las1 complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Las1l LAS1-like, ribosome biogenesis factor part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:60,851,969...60,873,717
Ensembl chr  X:60,851,962...60,873,687
JBrowse link
mitochondrial degradosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 part_of ISO (PMID:19509288), (PMID:29967381) RGD PMID:19509288 PMID:29967381 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696
JBrowse link
G Supv3l1 Suv3 like RNA helicase part_of ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:19509288), (PMID:29967381)
UniProt
Ensembl
RGD
PMID:19509288 PMID:29967381 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr20:30,378,542...30,399,076
Ensembl chr20:30,378,550...30,399,054
JBrowse link
nuclear exosome (RNase complex) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease part_of IBA
ISO
PMID:21873635
(PMID:20531386)
RGD PMID:20531386 PMID:21873635 RGD:13792537 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Exosc1 exosome component 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:240,734,777...240,745,518
Ensembl chr 1:240,734,773...240,745,438
JBrowse link
G Exosc10 exosome component 10 part_of ISO
IBA
(PMID:26166824)
PMID:21873635
RGD PMID:26166824 PMID:21873635 RGD:13792537 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Exosc2 exosome component 2 part_of IBA
ISO
PMID:21873635
(PMID:26166824)
RGD PMID:26166824 PMID:21873635 RGD:13792537 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
JBrowse link
G Exosc3 exosome component 3 part_of IBA
ISO
PMID:21873635
(PMID:11110791)
RGD PMID:11110791 PMID:21873635 RGD:13792537 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc4 exosome component 4 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
JBrowse link
G Exosc5 exosome component 5 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
JBrowse link
G Exosc6 exosome component 6 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Exosc7 exosome component 7 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:122,773,591...122,799,270
JBrowse link
G Exosc8 exosome component 8 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exosc9 exosome component 9 part_of ISO
IBA
(PMID:22791713)
PMID:21873635
RGD PMID:22791713 PMID:21873635 RGD:13792537 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Mphosph6 M phase phosphoprotein 6 colocalizes_with ISO (PMID:26166824) RGD PMID:26166824 NCBI chr19:45,860,152...45,870,077
Ensembl chr19:45,860,154...45,870,170
JBrowse link
G Mtrex Mtr4 exosome RNA helicase colocalizes_with
part_of
ISO
IEA
(PMID:26166824)
GO_REF:0000107
RGD
Ensembl
PMID:26166824 GO_REF:0000107 NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627
JBrowse link
G Nvl nuclear VCP-like colocalizes_with
part_of
ISO
IEA
(PMID:26166824)
GO_REF:0000107
RGD
Ensembl
PMID:26166824 GO_REF:0000107 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049
JBrowse link
G Wdr74 WD repeat domain 74 colocalizes_with
part_of
ISO
IEA
(PMID:26456651)
GO_REF:0000107
RGD
Ensembl
PMID:26456651 GO_REF:0000107 NCBI chr 1:205,631,769...205,636,563
Ensembl chr 1:205,631,824...205,636,563
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20010
    protein-containing complex 6011
      catalytic complex 1464
        exoribonuclease complex 25
          Las1 complex 1
          RNA polymerase II termination complex 0
          exosome (RNase complex) + 24
paths to the root